Pharmaron US Lab Services’ Post

Antibody-drug conjugates (ADCs) stand out as innovative biotherapeutics, but understanding their ADME properties during the discovery and development stages can be complex. This upcoming webinar can help! Join us today from 11:15 to 11:45 am, EST, as we share insights and strategies for ADC development at AAPS’s eCHALK webinar (free registration: https://hubs.li/Q02pSkjq0). Topics include: ✅ Payload release mechanisms ✅ Identification of catabolites in various in vitro systems ✅ Detection of drug–antibody ratios (DAR) ✅ The implementation of an integrated bioanalysis platform catering to both small and large molecules #aapscomms #adc #drugdiscovery #drugdesign #bioanalytical #dmpk #adme

Antibody-drug conjugates (ADCs) stand out as innovative biotherapeutics, but understanding their ADME properties during the discovery and development stages can be complex. This upcoming webinar can help! Join us today from 11:15 to 11:45 am, EST, as we share insights and strategies for ADC development at AAPS’s eCHALK webinar (free registration: https://hubs.li/Q02n6D9-0). Topics include: ✅ Payload release mechanisms ✅ Identification of catabolites in various in vitro systems ✅ Detection of drug–antibody ratios (DAR) ✅ The implementation of an integrated bioanalysis platform catering to both small and large molecules #aapscomms #adc #drugdiscovery #drugdesign #bioanalytical #dmpk #adme

Antibody-drug conjugates (ADCs) stand out as innovative biotherapeutics, but understanding their ADME properties during the discovery and development stages can be complex. This upcoming webinar can help! Join us on March 20th from 11:15 to 11:45 am, EST, as we share insights and strategies for ADC development at AAPS’s eCHALK webinar (free registration: https://hubs.li/Q02p6bq40). Topics include: ✅ Payload release mechanisms ✅ Identification of catabolites in various in vitro systems ✅ Detection of drug–antibody ratios (DAR) ✅ The implementation of an integrated bioanalysis platform catering to both small and large molecules #aapscomms #adc #drugdiscovery #drugdesign #bioanalytical #dmpk #adme

Antibody-drug conjugates (ADCs) stand out as innovative biotherapeutics, but understanding their ADME properties during the discovery and development stages can be complex. This upcoming webinar can help! Join us on March 20th from 11:15 to 11:45 am, EST, as we share insights and strategies for ADC development at AAPS’s eCHALK webinar (free registration: https://hubs.li/Q02n6CLb0). Topics include: ✅ Payload release mechanisms ✅ Identification of catabolites in various in vitro systems ✅ Detection of drug–antibody ratios (DAR) ✅ The implementation of an integrated bioanalysis platform catering to both small and large molecules #aapscomms #adc #drugdiscovery #drugdesign #bioanalytical #dmpk #adme

Antibody-drug conjugates (ADCs) stand out as innovative biotherapeutics, but understanding their ADME properties during the discovery and development stages can be complex. This upcoming webinar can help! Join us on March 20th from 11:15 to 11:45 am, EST, as we share insights and strategies for ADC development at AAPS’s eCHALK webinar (free registration: https://hubs.li/Q02n6ZZB0). Topics include: ✅ Payload release mechanisms ✅ Identification of catabolites in various in vitro systems ✅ Detection of drug–antibody ratios (DAR) ✅ The implementation of an integrated bioanalysis platform catering to both small and large molecules #aapscomms #adc #drugdiscovery #drugdesign #bioanalytical #dmpk #adme

Antibody-drug conjugates (ADCs) stand out as innovative biotherapeutics, but understanding their ADME properties during the discovery and development stages can be complex. This upcoming webinar can help! Join us on March 20th from 11:15 to 11:45 am, EST, as we share insights and strategies for ADC development at AAPS’s eCHALK webinar (free registration: https://hubs.li/Q02n6CLb0). Topics include: ✅ Payload release mechanisms ✅ Identification of catabolites in various in vitro systems ✅ Detection of drug–antibody ratios (DAR) ✅ The implementation of an integrated bioanalysis platform catering to both small and large molecules #aapscomms #adc #drugdiscovery #drugdesign #bioanalytical #dmpk #adme

Antibody-drug conjugates (ADCs) stand out as innovative biotherapeutics, but understanding their ADME properties during the discovery and development stages can be complex. This upcoming webinar can help! Join us on March 20th from 11:15 to 11:45 am, EST, as we share insights and strategies for ADC development at AAPS’s eCHALK webinar (free registration: https://hubs.li/Q02p6cnG0). Topics include: ✅ Payload release mechanisms ✅ Identification of catabolites in various in vitro systems ✅ Detection of drug–antibody ratios (DAR) ✅ The implementation of an integrated bioanalysis platform catering to both small and large molecules #aapscomms #adc #drugdiscovery #drugdesign #bioanalytical #dmpk #adme

Right now, there are more than 200 investigational siRNA drugs in development around the world. The relevance of early in-vivo PK studies cannot be overstated. Our latest article shines a light on the expanding role of siRNAs in the market and clinical research. We explore the importance of diverse bioanalytical platforms in understanding siRNAs' complex behavior in biological environments. We also included a case study to demonstrate the methodology's effectiveness. Learn more: https://hubs.li/Q02rkTnJ0 #dmpk #bioanalysis #siRNA #pharmacokinetics #drugdevelopment

🔎 Are you curious about AVITHRAPID's WP4 (Dompé farmaceutici SpA) ? 👀 Take a look below! 👇 📑 Work Packages ⚗ #Drugdiscovery is a multidisciplinary effort. AVITHRAPID brings together a team of highly skilled experts in molecular modeling, structural biology, assay development, toxicity profiling, antiviral drug discovery, animal model testing, and clinical trials. 🤳 Several partners have successfully worked on the discovery of novel antiviral substances. In addition, one pharma partner has identified a small molecule drug against #Zika #virus that is ready to enter #clinical #trials. 🔬 The unique portfolio of substances ranges from validated hits to pre-clinical candidates with proven in vivo efficacy. 💻 To further develop and validate this portfolion the AVITHRAPID consortium will work together in 8 Work Packages (WPs) which operate as an integrated pre-clinical drug discovery value chain.

Right now, there are more than 200 investigational siRNA drugs in development around the world. The relevance of early in-vivo PK studies cannot be overstated. Our latest article shines a light on the expanding role of siRNAs in the market and clinical research. We explore the importance of diverse bioanalytical platforms in understanding siRNAs' complex behavior in biological environments. We also included a case study to demonstrate the methodology's effectiveness. Learn more: https://hubs.li/Q02rkTnK0 #dmpk #bioanalysis #siRNA #pharmacokinetics #drugdevelopment