Actio Biosciences, Inc.’s Post

Folks, xBiologix is heading to #BIO2024 to connect solid phase tumor profiling with translational research & preclinical drug development. Join us in San Diego and learn how a simplified single staining step & multiplexed immunofluorescence makes profiling the required number of biomarkers available to virtually any research scientist or pathologist. #spatialbiology #multiplexIF

Very powerfull tools!

Single-cell multi-omics offers the promise of understanding cellular heterogeneity and complex processes, such as tumor progression. However, current studies rely on non-parallel methods that integrate modalities from different datasets (like transcriptomic and proteomics), muddling our view of cell types or states. Access to parallel methods measuring multiple omics modalities on the same cells is limited, with drawbacks like low throughput and lack of automation. We foresee significant progress in this field. What are your thoughts on these multi-omics challenges? And how should the field address them? https://lnkd.in/gigsZNN6 #bioinformatics #lifescience #genomics #multiomics

We were thrilled to welcome Dr. Ashleigh Riegler, a Postdoctoral Research Fellow at the University of Alabama at Birmingham, to our NanoString Technologies Customer Experience Lab. Dr. Riegler has been tirelessly working on the front lines of COVID-19 research, focusing specifically on Mycology in intubated COVID-19 patients with secondary mold infections. During her visit, she dove deeper into our CosMx SMI technology, which she is utilizing in her groundbreaking research. She is using our platform to spatially study iron concentrations in relation to these fungal infections, seeking to understand the crucial role that iron plays in infection outcomes. Her innovative approach includes comparing the gene expression of iron-loaded versus iron-low macrophages to gain new insights and hopefully develop more effective treatments. We are proud to support such important research and excited to see the results of Dr. Riegler's work. Stay tuned for more updates! #biotechnology #research #covid19 #mycology #geneexpression #nanotechnology #ironresearch #NanoStringTechnologies #CosMxSMI #CustomerExperienceLab #UAB This post may include information regarding CosMx™ SMI products for RNA detection, which products are not available in the member states of the European Unified Patent Court, as further described here - https://bit.ly/498JPIB.

Enhanced3D Genomics has a proprietary GenLink3D platform which uses capture Hi-C technologies to profile this 3D genome folding at high resolution for all genes and their enhancers simultaneously. The platform thus links gene enhancers and non-coding genetic variants to their target genes, unlocking their potential for therapeutic discovery Genetically supported drug targets are twice as likely to succeed in clinical trials (Sanseau et al., 2015). https://lnkd.in/ebuV89cE #enhanced3Dgenomics

Single cell multi-omics offers the promise of understanding cellular heterogeneity and complex processes, such as tumor progression. However, current studies rely on non-parallel methods that integrate modalities from different datasets (like transcriptomics and proteomics), muddling our view of cell types or states. Access to parallel methods measuring multiple omics modalities on the same cells is limited, with drawbacks like low throughput and lack of automation. We foresee significant progress in this field. What are your thoughts on these multi-omics challenges? And how should the field address them? https://lnkd.in/gigsZNN6 #bioinformatics #lifescience #genomics

Syncell is attending the Single-Cell Genomics Gordon Research Conference in Switzerland, ongoing until May 24th. This event explores how diverse cell types collaborate to enable tissue functions, with a focus on the intricate gene networks within cells. Technological advancements now allow for the detailed characterization of individual cells at the genomic scale within intact tissues. Single-cell and spatial omics methods, including proteomics, have emerged to measure various cellular properties with high spatial resolution. The conference unites life sciences and medical leaders with innovators in single-cell and spatial technologies to discuss recent advancements and their implications for diagnostics, therapeutics, and precision medicine. #GRC #SingleCellGenomics

Exciting news! Our group has submitted a second paper combining multiomics and digital twins for publication. This paper has significant implications in genomics research and could greatly reduce the time and cost of drug development. Stay tuned for updates on its publication and impact in the field. #genomics #drugdevelopment #multiomics #digitaltwins

The unveiling of high-definition (HD) Visium technology by 10x Genomics marks a significant leap forward, offering spatial transcriptomic readings at the single-cell scale. With a resolution of 2 µm, compared to the 55 µm of its predecessor, this advancement can be likened to constructing a colossal rocket for a moonshot project. This milestone in genomics heralds a new era of insights into disease biology, mechanisms of action (MOA) of drugs, and the identification of clinical biomarkers, all poised to revolutionize patient care. #spatialtranscriptomics #genomics #biomarker https://lnkd.in/g5jaZtTb

Shorten Your Path to Discovery with the Xenium In Situ Platform from 10x Genomics! Enabling single-cell spatial imaging of 1,000s of RNA samples, the Xenium platform for in situ analysis transforms the characterization of RNA and cells in fresh frozen or FFPE tissue. Uncover cell-cell interactions, understand structure and function, and explore how microenvironments change in health and disease. BioChain believes this platform will help our customers harness the full potential of this cutting-edge technology. Experience the power of the Xenium In Situ Platform with us: https://bit.ly/3Su7ux0 #biotechnology #10XVisium #xenium #genomics #biochain #research #biotech #spatialbiology #spatialtranscriptomics #spatialanalysis #spatialdata #cancerbiology #cancerresearch #cancer