Featured Scilight recently published in Biophysics Reviews! Authored by: Chunmei Zhou, Pingan Zhu, Ye Tian, Rui Shi, & Liqiu Wang #biomaterials #microfluidics #physics #biophysics Kit Parker Learn more 👇
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Our latest review article is now available online (https://lnkd.in/gbN6CJQC)! In this review, Jean-Francois Masson & I summarise the current state of play & future of AI-augmented nanotechnology & optophysiology, delving deep on tapered plasmonic nanosensor design, experimental set up & potential use for real-time chemical sensing pertinent to diagnostics & treatment assessment.
Machine Learning–Driven SERS Nanoendoscopy and Optophysiology
annualreviews.org
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Asst. Manager R&D at Oriental Aromatics Ltd || PhD (Organic Chemistry) Institute Of Chemical Technology
👩🏻🔬Excited to share our latest research article 🧑🏻🔬 Dear Connections, Excited to share that our latest research article, “Isomer engineering of benzofuran derived AIE luminogens: Synthesis, mechanochromism, pH responsive fluorescent switching, cell-imaging and Fe3+ sensing” has been published! In this study, through isomeric engineering of benzofuran-derived AIE luminogens, we observed a remarkable shift in their photophysical properties. Integrating TPE into the benzofuran core produced a mechanofluorochromic luminogen, while modifying the side chain with TPE enhanced luminogenic performance and introduced cell-imaging capabilities. Check out the full article https://lnkd.in/dWQpKbUN Abstract: The influence of multiple factors often leads to the unexpected performances of the designed AIEgens. It is difficult to precisely conclude the influence of the substituted sites and role of isomers on the photophysical properties of the AIEgens which therefore brings uncertainty in the molecular design strategies. Isomer engineering of AIEgens is a less explored domain. There are only a few reports that substantiate the effects and positions of the substituents on the AIE properties. The present investigation explores two isomeric benzofuran-derived luminogens GBY-1 and GBY-4, both featuring a TPE moiety and showcasing AIE and AIEE properties respectively inherited from TPE. The isomeric effect resulting from TPE incorporation at different positions across benzofuran significantly influenced their photophysical properties, mechanofluorochromic properties, and AIE effect. Their distinctive luminogenic features were evident in mechanochromic property as well as in cancer cell imaging. GBY-1 was found to be uniformly dispersed in the cytoplasm, not co-localized with the nucleus, while GBY-4accumulated near the cell membrane. Furthermore, post-functionalization of one of the luminogens, GBY-1, derived another AIEgen, GBY-5 with a dramatic improvement in the PLQE along with its ability to selectively sense Fe3+ in aqueous environments, within a detection limit of 0.00035 mM. I am thankful to my research supervisor Dr. Satyajit Saha for his constant guidance and encouragement. I would like to acknowledge #SARTHI for providing financial support. Congratulations to all authors. #Research #Innovation #MaterialScience #AIE #Luminogens #sensing
Isomer engineering of benzofuran derived AIE luminogens: Synthesis, mechanochromism, pH responsive fluorescent switching, cell-imaging and Fe3+ sensing
sciencedirect.com
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A general fluorescence off/on strategy for fluorogenic probes: Steric repulsion-induced twisted intramolecular charge transfer (sr-TICT) SCIENCE ADVANCES https://lnkd.in/gymTU9xf
A general fluorescence off/on strategy for fluorogenic probes: Steric repulsion-induced twisted intramolecular charge transfer (sr-TICT)
science.org
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🔬Scientists have made progress in understanding the transition from solid to plasma induced by intense laser pulses. 🚀This advancement opens doors to novel applications like laser-based proton therapy for cancer treatment and fusion energy research. 🔍In a recent publication in Light: Science & Applications, an international team of researchers introduced an innovative all-optical single-shot probing technique. 🌟This technique allows complete visualization of the target's dynamics during the ultrafast solid-to-plasma transition, providing unprecedented insights into fundamental processes. 💡Understanding these dynamics is key to improving laser ablation performance and making laser-driven ion acceleration viable for industries and medical applications. 🤯From micromachining to cultural heritage analysis, the implications are vast! 🌐 📚Read more: https://lnkd.in/g5vby5f4 . . . . . . . . . . . . . . #Science #Technology #Innovation #LaserScience #PlasmaPhysics #Research #Innovation MedBound Times NewsGram M Subha M. Sonali Pradhan Jyoti Shukla Susmita Bhandary Munish Kumar Raizada, MD, FAAP Himani Negi Nirainila Joseph Aniket Bakare Akashita Panjla Dr Pragati Priya Aditi Anup Madathingal Arpit sharma Dr.Amingold M J Rasheeka MP Yogeeta V. Priyanka Pandey Aditi Anup Madathingal
Optical Probing of Ultrafast Laser-Induced Solid-to-Overdense-Plasma Transitions
medboundtimes.com
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A new tool could reduce the cost of diagnosing infectious diseases. Researchers have developed a new, less expensive means of detecting nuclease digestion, one of the critical steps in many nucleic acid detection applications, such as those used to identify COVID-19 and other infectious diseases. A new study published in the journal Nature Nanotechnology shows that this inexpensive tool, called Subak, is effective in determining when nucleic acid cleavage occurs, which happens when an enzyme called nuclease breaks down nucleic acids, such as DNA or RNA, into smaller fragments. The traditional method for identifying nuclease activity, the Fluorescence Resonance Energy Transfer (FRET) probe, is 62 times more expensive to produce than the Subak reporter.
A non-FRET DNA reporter that changes fluorescence colour upon nuclease digestion | Nature Nanotechnology
nature.com
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New Series on Nanotechnology in Medicine - Part 3 - Nanotechnology in Regenerative Medicine #MythicalMicrobe #ScienceIlluminated #nanotechnology #nanomedicine #nanoparticles #tissueengineering #tissuerepair #nanocarriers #scaffolds #nanofibres #celldamage #extracellularvesicles #targettissues #targetcells #therapeuticdrugs #genedelivery #drugdelivery #controlledrelease #stemcelltherapy #antiinflammatory #antioxidant #sciencecommunication #scienceeducation #sciencefacts #science #research #medicine
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How can you spot novel applications and the materials making them possible in a complex field like #nanotechnology? By analyzing the co-occurrence of key concepts, we’re identifying the most likely sources of scientific breakthroughs. Learn more: https://ow.ly/cr9o50SUUfy #nanoplastics
Nanotechnology co-occurrence analysis
cas.org
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An optical plasmonic tweezer-controlled surface-enhanced Raman spectroscopy (SERS) platform developed by The Hong Kong University of Science and Technology (HKUST) enables efficient, high-throughput, single-molecule characterization in solution. #photonics #BioPhotonics
Optical-Plasmonic SERS Platform Clocks Molecular Systems
photonics.com
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Integrating Nanotechnology and Artificial Intelligence 1.Precision Medicine 💊 in Nanotechnology Nanogenetics is coming soon Genetics +Nanotechnology =Nanogenetics
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