Akinwale Faniyi’s Post

Third-generation sequencing, also referred to as long-read sequencing, represents a category of DNA sequencing techniques that generate lengthier sequence reads. In comparison to second-generation sequencing, commonly known as next-generation sequencing, third-generation sequencing technologies have the capacity to produce significantly longer reads. This characteristic bears significant implications for genome science and broader biological studies. Who invented this and when? Third-generation sequencing was developed by Pacific Biosciences (PacBio) and Oxford Nanopore Technology (ONT) and has been under active development since 2008.   What are the companies leveraging it? Some big names that are leveraging this innovation are Pacific Biosciences of California, Genia Technologies, Stratos Genomics, GATC Biotech AG, Phase Genomics, and Loop Genomics. #BioAngelsBiotechChronicles #BioAngels #HealthcareInnovations #HealthcareSolutions

We’re paving the way through our collaboration with CiberMed to enable a new Targeted Digital Cytometry method from bulk RNASeq data! If you are doing immune cell profiling but need a way to scale your sample numbers or address tissue dissociation bias, this method might be for you! #targetenrichment #digitalcellprofiling #cellprofiling #immunecellprofiling #deconvolution #rnaseq #cibermed

🔬🚀 "Innovation is like a speeding train – it keeps accelerating!" 🚀🔬 Just look at the journey of genomic technology. In 2013, sequencing a human genome cost $5,467. Fast forward to 2023, and it’s now just $𝟐𝟎𝟎 𝐩𝐞𝐫 𝐠𝐞𝐧𝐨𝐦𝐞 - a staggering 96% decrease! 📉 To put that into perspective, you can now sequence your own genome for the price of a new pair of quality shoes! This incredible progress highlights the rapid advancements in genomic technology. As biotech enthusiast, it's thrilling to see how accessible and efficient genome sequencing has become. These advancements are paving the way for exciting new possibilities in research and personalized medicine. If you’re as fascinated by this and want to dive deeper into the world of genomics, check out our work at GeneTiCA Group by visiting our website at https://www.genetica.cz/ #Genomics #Innovation #Biotechnology #GenomeSequencing #TechAdvancement #GeneTiCA #GetToKnow

Here at the #LorneCancer conference. Come visit our booth, and talk to us on how we can help with your Cell Biology, Genomics and Drug Discovery workflows. #Tecan

🧬 New Developments in Single-Cell Transcriptomics! 📊 A recent study by Lucas Kuijpers and colleagues, published in BMC Genomics, evaluates into the efficiency of various bioinformatic pipelines for SPLiT-seq, a different approach for single-cell transcriptome sequencing. 🛠️ SPLiT-seq is a single-cell transcriptome sequencing technique that uses a combinatorial barcoding approach by splitting and pooling cells into multi-well plates with barcodes, recently commercialized by Parse Biosciences 📊 Evaluated pipelines include STARsolo, splitpipe, and alevin-fry splitp among others, highlighting their ability to handle large datasets effectively 🔎 While STARsolo and splitpipe are recommended, STARsolo requires additional coding. 📚 BMC paper: https://lnkd.in/dzaw--qB 👩💻 STARsolo: https://lnkd.in/d2vmaDPG 👩💻 splitpipe: https://lnkd.in/dxnFgbPs 📢 Join the Conversation 📢 Share your ideas, methods, and tools in the comments! 👇 💬 #Genomics #Bioinformatics #Transcriptomics #Biotechnology #SPLiTseq

good opportunity

Working with Tissue DNA Isolation optimization... Formulation of Enhanced Lysis Buffers... Good Laboratory Practices Research and Development VETA Genomics . #molecularbiology #genomics #researchanddevelopment #validation #dna #moleculargenetics #biotechnology

What could you discover with highly accurate long-read sequencing at scale? The submission window is now open for the 2024 Microbial Genomics SMRT Grant. Tell us in 100 words or less how HiFi sequencing will advance your microbiome and metagenomics research for a chance to win free sequencing! Details on how to apply: https://bit.ly/3z89XFJ #PacBio #Metagenomics #MicrobialGenomics

[𝗠𝗲𝗲𝘁 𝘁𝗵𝗲 𝘀𝗰𝗶𝗲𝗻𝗰𝗲] Did you know that the discovery of the double helix structure of DNA 🧬 by James Watson and Francis Crick in 1953 revolutionized the field of molecular biology? It provided a deeper understanding of how genes control cellular processes and led to groundbreaking insights into the genetic code and protein synthesis. This discovery also paved the way for the development of the #biotechnology industry. One of our common priorities is to develop #genetherapies that have the potential to positively impact the lives of the patients and families devastated by rare and life-threatening genetic diseases. At Novartis, we are enthusiastic about the science behind our work, breaking barriers, and finding answers to difficult questions. #reimaginingmedicine #innovation #DNA #science

🔬 New Technology for Spatial Genomics! 🧬 Check out the recent study "Slide-tags enables single-nucleus barcoding for multimodal spatial genomics" published in Nature by Andrew J. C. Russell et al. 🚀 Slide-tags allows tagging single nuclei within intact tissue sections using spatial barcode oligonucleotides from DNA-barcoded beads with less than 10 μm spatial resolution and high-quality whole-transcriptome data. 🧫📊 🔵 Adaptable to various single-cell measurement technologies, including multiomic measurements of open chromatin, RNA, and TCR sequences. 🟠 Successfully used in the human cortex to uncover cell-type-specific spatial gene expression patterns and identify spatially varying genes systematically. 🟣 Analyzed densely packed tissues like the human tonsil, identifying subpopulations and spatially varying genes in germinal center B cells, T follicular helper cells, and follicular dendritic cells. 🟢 Achieved higher spatial resolution and molecular sensitivity compared to existing approaches. 📚 Nature paper: https://buff.ly/3RnwqUR 📢 Join the Conversation 📢 Share your ideas, methods, and tools in the comments! 👇 💬 #Genomics #SpatialGenomics #SingleCell #Bioinformatics #Pharma #ResearchInnovation #Biotechnology #LifeSciences #NatureResearch