Akouos’ Post

New in The Innovation Medicine! The rapid development of gene-editing technology is making xenotransplantation increasingly common in clinical practice. Zhang et al. summarized recent progress and potential issues that might be encountered in the large-scale clinical application of xenotransplantation. Read more @Innov_Medicine https://lnkd.in/eADsQnjR #medicine #clinic #transplant #research #innovation

Regenerative medicine can be an amazing therapeutic option for functional recovery, but it has to be the RIGHT option for the RIGHT patient and done RIGHT! It’s important that the FDA appropriately enforces these guidelines to ensure that the field of regenerative medicine can fulfill that most basic tenet that should guide all medicine: first do no harm. You can learn more about the science, evidence, and regulations surrounding regenerative medicine from Don Buford, MD and his informative posts. https://lnkd.in/gERkpnZM

Three great articles have recently been published where the authors have used our Coremine Medical tool for their data analysis. The articles were published in the high-impact journals Scientific Reports from Springer/Nature, Frontiers in Medicine, and Heliyon from Cell Press. Read more about the exiting results and how they used Coremine Medical at https://lnkd.in/diSf-VpZ.

#Clinicaltrials are not only the practical application of changes and discoveries in medicine; they are subject to changes too which usually happen very gradually. Read this article to explore how the trends of 2023 are impacting the evolution of clinical trials in 2024. https://bit.ly/4dsVTXk

A team of PathAI scientists including Hanna Pulaski, Neel Patel, Hypatia Hou, and Andrew Beck have recently published a new study titled “Validation of a whole slide image management system for metabolic-associated steatohepatitis for #clinicaltrials” in the Journal of #Pathology: Clinical Research. 📝 Read the publication: https://lnkd.in/e3J4A3hw Metabolic dysfunction-associated steatotic liver disease (MASLD) affects approximately 25% of the global population, and metabolic-associated steatohepatitis (MASH) is now a leading cause of liver transplants. In clinical trials for MASLD #drugdevelopment, glass slides manually read by a pathologist are the gold standard for assessing of #liver #biopsy specimens. However, the need for shipping physical slides from central laboratories to study pathologists risks physical damage to the slides and can result in a slow process. Slide assessment using #digitalpathology may be an accurate and efficient alternative to manual glass slides for evaluating MASH in clinical trials and further addresses key challenges such as endpoint enrollment. Our study demonstrates that the use of digital images on the AISight® Clinical Trials platform yields results equivalent to the use of glass slides for evaluating disease activity in steatohepatitis, streamlining pathologist evaluations and reducing logistical hurdles, thus making #digitalpathology a promising approach for future #clinicaltrials. Learn more about AISight® for #clinicaltrials: https://lnkd.in/eGHH7iFT AISight® is for research use only. Not for use in diagnostic procedures. #AIPathology #biotech #healthtech

Hear a panel of experts on #ChronicLymphocyticLeukemia review patient cases, the latest research presented at ASCO 2024 and surrounding meetings, and provide insights on evolving clinical practices. #Hematology Watch here: https://lnkd.in/eheCr6K9

This article explores the use of #longreadsequencing in #clinicalgenomics and medical research, highlighting its potential applications, but also highlighting its limitations. #genetictesting #genomictesting #genomicmedicine https://lnkd.in/dqT9vRSE

🌐⚕️ Screening in Clinical Trials⚕️🌐 Contrary to common belief, participants are not simply placed into clinical trials. Screening is a crucial step where research staff inquire, test, and evaluate eligibility based on specific criteria. 🔍 What does screening involve? - Questions about medical history, family background, and lifestyle. - Various tests: blood, laboratory, and physical examination. 📋 Inclusion Criteria: - Certain characteristics needed for eligibility (e.g., disease stage, gene version, family history). 🚫 Exclusion Criteria: - Factors like health conditions or medications that could interfere with the treatment. 👥 Importance of Screening: - Ensures participants meet criteria for safety and effectiveness. - Many volunteers are screened to find the right fit for each trial. 🔄 One Trial at a Time: - Generally, participants can be in only one clinical trial simultaneously. As can be seen, participating in research is a thoughtful journey! 🌟 #ClinicalTrials #Screening #HealthAwareness

What is Translational Medicine? Translational medicine (also referred to as translational science) is a discipline within biomedical and public health research that aims to improve the health of individuals and the community by “translating” findings into diagnostic tools, medicines, procedures, policies and education. From: https://lnkd.in/eSd428sQ. #medicine #translationalmedicine #patientcare #communication #education #medicaleducation #clinicalresearch #medicalaccess