It is International Vasculitis Day! Today we shine a light on #vasculitis and in particular ANCA-associated vasculitis (AAV). Vasculitis is used to describe a family of nearly 20 rare autoimmune diseases characterized by inflammation of the blood vessels which can damage vital organs. In the majority of AAV cases the kidneys are affected, and this often leads to significant or total loss of kidney function. At Alentis we are determined to develop lixudebart (ALE.F02) an investigational treatment to recover kidney function in AAV patients. Find out more on https://lnkd.in/gZPXSBa #VasculitisAwareness #vam2024 #ANCAVasculitis
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Co-Director, UVA Health Aortic Disease Program | Associate Professor of Surgery, Division of Cardiothoracic Surgery, Department of Surgery, University of Virginia School of Medicine | Opinions are my own
Sexagenarian with history of DeBakey type I aortic dissection, S/P ascending/hemiarch replacement (recent; within 5 yrs prior to presentation), CKD 3a, Crohn’s disease, S/P total proctocolectomy + end ileostomy (remote), now with large, chronically dissected extent II #thoracoabdominal aortic aneurysm (#TAAA) with large clot burden in false lumen causing DIC and bleeding diathesis, treated with open extent II TAAA repair, island patch reimplantation of T9-11 intercostals, aorto-celiac/aorto-SMA bypasses, and aorto-R renal/aorto-L renal bypasses, ligation of IMA #aortaed
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🌟 Revolutionizing Treatment: Introducing LYCOLATE 🌟 🚑 Targeting specific diseases with precision! LYCOLATE I.M./I.V. Injection, containing 0.2mg/ml of glycopyrrolate, is your ally against conditions related to excessive cholinergic activity. 💊 🎯 Therapeutic Focus: - Disease A: LYCOLATE provides relief by effectively inhibiting cholinergic responses. - Disease B: Combat symptoms associated with overactive muscarinic receptors. 🌈 Clear, Colorless Solution: Ensure your journey to recovery is supported by the purity of LYCOLATE. 🔬 Stay ahead in the fight against disease! 💪 #LYCOLATE #MedicalInnovation #DiseaseTreatment #HealthcareAdvancement #EverestParenterals #RanasariaGroup More Info: https://lnkd.in/gA_Ad48u Note: Only to be taken under the guidance of Medical Professionals.
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In case you missed it - the #VetScienceWeek24 Preliminary Program is out now👉 https://lnkd.in/gN2SZUNd Check out 3 days of session topics such as: 📌Infectious disease and the eye. 📌Anaesthesia drugs with behavioural implications. 📌Do you suspect pulmonary hypertension? 📌Diagnostic bias: it affects vets too. 📌Cardiac involvement in systemic diseases #ANZCVS #vetscience #VSW24 #VedEducation #Vet
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This study including more than 23,000 statin-treated patients with ischemic heart disease and well controlled low-density lipoprotein cholesterol (LDL-C) levels, confirms non-high-density lipoprotein cholesterol (non-HDL-C) as a simple and robust measure to identify patients who have a high residual risk. Learn more about the results of this study on our website. ➡️ https://lnkd.in/eHnkqYd4 #R3i #ResidualRisk #ResidualRiskReduction #MedicalResearch #Cardiovascular #CVD #CardiovascularDisease #CardiovascularHealth #IschemicHeartDisease #Lipoprotein #Cholesterol #HDL #LDL #NonHDLcholesterol
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Selexipag shows promise for treating pulmonary arterial hypertension associated with connective tissue disease (CTD). The ongoing EXPOSURE (EUPAS19085) study sheds light on the real-world management of PAH-CTD patients in Europe and Canada. Authors: Sean Gaine, Pilar Escribano, Audrey Muller, Catarina Fernandes, PhD, Martina Fontana, Tatiana Remenova, Stefan Söderberg and Tobias J Lange. #connectivetissuedisease #CTD #pulmonaryhypertension #pulmonaryarterialhypertension #PAH #chronicthromboembolicpulmonaryhypertension #CTEPH #knowledgesharing #knowledgeexchange #patientempowerment #patienteducation #allianceforph #organtransplant #organdonation #transplant #lungtransplant HTaPFrance Stichting Pulmonale Hypertensie / PH Association the Netherlands PH Belgium - Pulmonale Hypertensie vzw AIPI Italian Pulmonary Hypertension Association Pulmoner Hipertansiyon ve Skleroderma Hasta Dernegi Hellenic Community for Pulmonary Hypertension Pulmonale Hypertonie E.V. Ieva Plume PHA Polska PHA Japan https://lnkd.in/d2mgBA38
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IRD is a consortium of the Bulgarian Association for Promotion of Education and Science, "RareDis” Medical Centre, Centre for Health Technology Assessment and Analysis and RareDis Solutions
Insights on Pulmonary Alveolar Proteinosis (PAP)! We share a comprehensive review on Pulmonary Alveolar Proteinosis (PAP), an ultra-rare disease stemming from impaired pulmonary surfactant clearance due to alveolar macrophage dysfunction or their signaling pathways. Key highlights include: -In-depth classification and pathogenesis of PAP -Clinical presentation and diagnostic approaches -State-of-the-art treatment options, with whole-lung lavage being the gold standard -Recent findings and areas needing further investigation Read the full article: https://lnkd.in/dbnQ8qE2 #PulmonaryAlveolarProteinosis #RareDiseases #MedicalResearch #HealthcareInnovation #LungHealth #AutoimmuneDisease #MedicalReview #PAPResearch #WholeLungLavage
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MannKind announced today that it will proceed with a first-in-human Phase 1 study of nintedanib DPI (MNKD-201) for pulmonary fibrotic diseases – including idiopathic pulmonary fibrosis (IPF). According to @PulmonaryFibrosisFoundation, there are more than 250,000 Americans living with pulmonary fibrosis (PF) today with 50,000 new cases diagnosed each year. Sadly, as many as 40,000 Americans die from IPF each year. MannKind now has two studies in motion that will explore the potential treatment options for patients living with serious lung diseases. https://bit.ly/3Wio8lg #MNKD #Pulmonary #Lungs
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🩸 #Thalassemia is an inherited blood disorder that causes the body to produce less than the usual amount of hemoglobin. It is estimated that more than 100 million people worldwide carry genes responsible for thalassemia and that annually more than 300,000 babies are born each year with severe forms of the disease. 🔎 At Bristol Myers Squibb we put the focus on the importance of access to early diagnosis and therapies that improve the quality of life of #patients, as many of them face severe clinical complications. Find out more about thalassemia on the Thalassaemia International Federation (TIF) website ➡️ https://lnkd.in/eRA4Bhy #ITD2024 #BeAwareShareCare #TreatmentForThal #TreatmentForAll #InternationalThalassemiaDay #BMSIberia #BMSPortugal #BMSCommunity #BMSTransformingLives #WorkingTogetherforPatients #BMSTransformingPatientsLives
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What would you (or your child) do if you didn’t have to worry about lows? Learn more about HI clinical trials for a #FutureWithoutLows here: https://lnkd.in/eFM8cuE #hyperinsulinism #raredisease #congenitalhyperinsulinism #hypoglycemia | Hyperinsulinism | Congenital | HI | Hypoglycemia | Rare Disease
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Clinical significance anti-Ro60/SSA and anti-Ro52/TRIM21 autoantibodies in SLE (Australian cohort, n = 409 patients): 🔹Anti-Ro positivity is common (47.2%) and is associated with higher disease activity, as well as with higher frequency of specific target organ associations such as cutaneous and haematological disease. These patients also have a high frequency of proteinuria. 🔹Anti-Ro positive patients are more likely to receive glucocorticoids and immunosuppressants. 🔹Anti-Ro positive SLE patients may fulfil Sjögren’s criteria and experienced many extra-glandular features. 🔗https://lnkd.in/dABGyyRY
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3moAny plans for retroperitoneal fibrosis?