CRISPR-Cas9 in agriculture‼️
CRISPR-Cas9 technologies can be used to edit the genome of agricultural crops, potentially improving photosynthesis and crop yields in a variety of ways.
What are CRISPR-Cas9 technologies?
You learned all about the basics of CRISPR-Cas9 technologies. CRISPR are detectable sequences of DNA that act as an adaptive immune system within prokaryotes such as bacteria. Cas9 is an endonuclease that can cut and glue DNA back together. Importantly, Cas9 can be instructed by CRISPR to target specific DNA recognition sites to cut and join, altering the DNA.
This makes the CRISPR-Cas9 pairing one of the most iconic duos since Bert and Ernie, Han and Chewie, or the Veronicas. CRISPR-Cas9 technology can therefore be utilised to genetically modify an organism’s genome. An important application of CRISPR-Cas9 is removing unwanted or disadvantageous alleles within an organism’s genome. This can result in an improved or desired phenotype. The new and improved genetically modified organism (GMO) can then adapt to and survive its environment more effectively.
Why do we need to improve photosynthetic efficiencies and crop yields?
You learned about the function of Rubisco and how it can initiate photorespiration which decreases the efficiency of photosynthesis. Recall that C3 plants have no adaptations to limit photorespiration, whilst C4 and CAM plants do. The most abundant plants on Earth – C3 plants – also encompass most agricultural crop species that we rely upon for food. By 2050, it is predicted that agricultural productivity will need to almost double to cope with the demands of the rising global population. Climate change, however, has the potential to significantly reduce crop yields globally and arable land is already largely exhausted. Furthermore, clearing more land releases greenhouse gases into the atmosphere. Therefore, the situation is as follows: we need to get more out of the land we use. That is, agricultural yields need to increase while using the same amount of agricultural land. This is where gene editing comes in. Editing crop genomes could enable farmers to maximise crop productivity without clearing any additional and.
Genetic engineering could be used to increase the productivity of crops such as tomato or wheat.
#biotech #biotechnology #geneticengineering #tissueculture #agriculture
Co-Founder & CEO at Moolec Science (NASDAQ:MLEC)
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