American Society of Nephrology’s Post

Triall Insights 🔍 Late-stage clinical research has become increasingly complex. According to Tufts CSDD, a typical Phase III clinical trial conducted during 2016-2021 collected an average of 25.8 endpoints. This number is 37% higher compared to 2015, signalling a sharp increase in clinical trial complexity. The research report notes that around 25% of study procedures in Phase III studies contributed to supporting secondary, tertiary, and exploratory endpoints. Source: https://lnkd.in/dSYX898E #clinicaltrials #clinicalresearch #protocol #endpoints #eClinical

On May 20th, we celebrate International Clinical Trials Day, highlighting the importance of clinical trials. Without clinical trials promising medications cannot reach patients.   Did you know that there are approximately 490,000 studies registered worldwide? Did you know that Belgium and the Netherlands are European leaders in clinical trials?   Discover more and consider participating in clinical research. Together we can cure: https://lnkd.in/dZzdeMY 💊🤝🧡   #clinicaltrialshelp #clinicaltrials #togetherwecancure #joinclinicaltrials

𝗖𝗹𝗶𝗻𝗶𝗰𝗮𝗹 𝘁𝗿𝗶𝗮𝗹 𝗰𝗼𝗺𝗽𝗹𝗲𝘅𝗶𝘁𝘆 𝗶𝘀 𝗼𝗻 𝘁𝗵𝗲 𝗿𝗶𝘀𝗲 … 📈 … and this goes hand in hand with an increase in protocol amendments. In 2024, multiple great research publications addressed the topic of increasing trial complexity and prevalence of protocol amendments, and the stunning toll that protocol amendment implementation takes on clinical trial timelines and costs. Trial complexity isn’t all bad and is sometimes needed, such as in clinical trials targeting rare diseases or more narrowly defined patient populations, or to address specific unmet medical needs or regulatory requirements. ✔ In some cases, however, complexity may be unnecessary, and protocol amendments could be avoided. ❌ Swipe through the carousel below to discover how leveraging 𝗵𝗶𝘀𝘁𝗼𝗿𝗶𝗰𝗮𝗹, 𝗰𝗹𝗶𝗻𝗶𝗰𝗮𝗹𝗹𝘆 𝗿𝗲𝗹𝗲𝘃𝗮𝗻𝘁 𝗱𝗮𝘁𝗮 (like what we curate in TA Scan) can help simplify clinical trial protocols in several ways. 👇  #ClinicalResearch #ClinicalTrials #clinicalintelligence #DataScience #TAScan #ProtocolDesign #DrugDevelopment

How can people who are patients and clinical trial investigators work together to deliver better, innovative therapies quicker and address true unmet need? Through the systematic use of Patient and public involvement (PPI) in clinical trials. The team at Department of Clinical Research (DCR), University of Bern are actively working with both sides to help in capacity building to advance these types of partnerships. Visit their YouTube channel to gain some insights https://lnkd.in/eJuWJvDF Link to their page in the comments #PPI #patientvalue #clinicaltrialinnovation #EmpoweringPeopleWhoArePatients

We're looking forward to our webinar with XTalks next week! Check out the post below for details about the presentation and for info on how to register ⬇️⬇️⬇️

Incorporating the patient voice in clinical trial design is not just beneficial, it's essential! By understanding and integrating patient perspectives, trials can become more patient-centric, leading to improved participation and retention rates. This approach ensures that the trials are not only clinically relevant but also resonate with the real-world experiences and needs of the patients. The webinar sounds like a fantastic opportunity to delve deeper into this crucial aspect of clinical research. Looking forward to gaining insights and strategies on how to effectively include patient voices in every stage of clinical trials. #PatientCentricity #ClinicalTrials #ResearchInnovation #HealthcareEvolution 🌟🔬👥

Patient-Centric Clinical Trial Designs I am excite to share Patient Centric clinical trial design in this presentation We will be Exploring the evolving landscape of clinical trials that prioritize the unique needs and experiences of patients. This section will provide an overview of the key principles and benefits of patient-centric approaches.

FREE webinar to attend https://lnkd.in/gRkpw8kc Clinical trial protocols often focus on the clinical objectives of the trial, without considering the implications of the design on the patients participating in the trial from a practical and emotional impact perspective, as well as outcomes and endpoints that matter most to patients. This can contribute to lower trial participation, increased drop-out rates, and reduced operational efficiency.   Could incorporating the patient voice in clinical trial design and execution address these issues? We will discuss the challenge and importance of including patients as partners in research, and the potential for more consistency in patient inclusion, including research methods and approaches designed to ensure patients have authentically shaped trial designs.   Find out with Fabian Sandoval, MD (Emerson Clinical Research Institute), Scott Schliebner (Rare Clinical), Carla V. Rodriguez-Watson, PhD, MPH (Reagan-Udall Foundation for the FDA), Rebecca Nash (Oracle Life Sciences), and Kathy Beusterien (Oracle Life Sciences). #patientcentricity #clinicalresearch #clinicalinnovation #digitaltransformation #clinicaltrials #webinar

In clinical trials we conduct as Element Research Group, we observe study delays which can at times fixed by adjusting Inclusion/Exclusion criteria and better Site Selection. In addition, there are several actions Sponsors and CROs take when the Study is in progress to help with enrollment and prevent study delays. As SiteAI, our Clinical Trial modules are designed to address these issues and help Clinical Trials meet their deadlines. The benefits for Sponsors to complete the CT process 12 -18 months earlier are immense! And we can help make that happen! Ask us how! #clinicaltrials #clinicalresearch #clinicaldevelopment #artificialintelligence #studydesign

Watch this video to see the remarkable results of the controlled clinical trial for Lenire. Lenire's TENT-A3 controlled clinical trial results have recently been independently reviewed and published in Nature Communications. Learn more about the landmark clinical trial by visiting https://zurl.co/GDVD