ACMG - American College of Medical Genetics and Genomics’ Post

Last week’s TRICALS Masterclass, held in Amsterdam, was a huge success. With an engaged audience of about 120 participants representing a variety of industries, the Masterclass created an environment of free-flowing conversation with a variety of perspectives and opinions as well as thought-provoking questions Can we now consider Microfilaments as a possible primary endpoint in ALS studies? Should we now exclude placebo arms in early phase studies? What do we need from a Phase II study to confidently start a Phase III study? And what does a successful Phase III study look like? After two days of great discussion, here are some general take-home messages:  🟢 Clinical relevance should always take the patient’s perspective into account 🟢 Clinical studies should run for at least 6-9 months in Phase II and 12 months in Phase III 🟢 Good safety data, positive changes in Neurofilaments, and a positive change in a clinical marker (such as ALSFRS-R) should be available prior to starting a Phase III study 🟢 All Phase III controlled studies should include an Open Label Extension A big thank you to Professor Leonard van den Berg and the whole TRICALS team on a very successful, interactive, and informative #Masterclass. We're already looking forward to next year!

#medtech #neurotech innovators check out this upcoming course!

What makes learning medicine so effective and smooth? Here at MUA, it's all about our amazing professors who light the way for our med students! Share a favorite lesson or memory from a professor below! #MedicalUniversityoftheAmericas #MUAMed #MedSchool #CaribbeanMedSchool #CaribbeanMedStudent

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It’s been an exciting few days in Vienna at #UEGweek24 ! Having sat through some key data releases and symposia I’m more convinced than ever that practicing physicians don’t care about the data dump. For sure the data is important but what they really want is the “so what does this mean to me and my patients, what are the implications and how do I apply this in practice?” They count on reputable knowledgeable top-tier faculty that basically sign off the validation of the data and can provide practical and pragmatic guidance about the cutting science! P.S. Practicing physicians update their scientific knowledge online while scrolling, like you and me…. (and they don’t go back to first or second year medical school that is typically the first 2 presentations in a symposium!!), they want highly focused Microburst education in a clean simple no-distractions format. Reach out for a catchup if we didn’t manage to share a coffee/tea/hot chocolate over the last 3 days. #MedicalAffairs #CME Answers in CME (AiCME)

I have no idea why this video got more than 300K views. it was not the best we produced, However. i kept watching it and reached a conclusion. it tackles a point that is not discussed openly: Even in Randomized Controlled Trials RCTs we can not eliminate bias. I think this should be discussed in the context of influencing the clinical decisions. https://buff.ly/4csjGEO #ClinicalEvidence #RCTs #ClinicalResearch #RWE

#EHA would like to congratulate this year's #EHACRTH scholars on completing the first workshop. We would also like to thank our faculty for providing their insights into how to get trial funding, working with the industry, patient safety and reporting, how to improve your working relationship with statisticians, and more. Learn more about CRTH:

As I head out to ACR 2023 I reflect on the incredible progress made over the last 20 years. Remission is now a real target for treatment in RA, AS has been redefined and there are a great range of new therapies in PsA and incredible results in the skin. In Lupus new therapies have arrived and many more being developed with new outcome measures. It is a testament to a great collaboration between academics, industry and of course patients. You can keep abreast of latest developments from #acr23 and beyond on cytokinesignalling.com and lupus-forum.com

Greetings from Fineness Institute of Clinical Research!!! we are booking seats for 2024 batches visit www.finenessinstitute.com to book today  Last and final call to enroll before 10th feb 2024 Personalised Attention guaranteed #clinicalresearchtraining #clinicalresearch #researchtraining #clinicaltrials #academicresearch#pharmacovigilancetraining #pvtraining #pvprofessional #pvcareer #pvjobs#clinicaldatamanagement #clinicaldatatraining #cdmg #cdat #cdmtraining

Since I would like to acquire knowledge, I worked on this course. I still need to learn it more but I completed this one. StanfordOnline CME.20651 Thinking Critically: Interpreting Randomized Clinical Trials