ARRALYZE’s Post

It all started with a vision at ARRALYZE, a division of LPKF Laser & Electronics SE. A dream of changing the world, breaking barriers, read below for the story of the latest breakthrough in single cell analysis.

🔬SPIE, the international society for optics and photonics Photonics West 2024 trade show is in full swing, this week we present our topics on site in San Francisco and here on LinkedIn. Let's start with our marker-free #detection using #photonic #biosensors for #bio and #health applications. 🔍 Label-free detection methods - i.e. without additional reagents for molecular characterisation - have a high development potential as they can provide simpler diagnostic tools that can be used outside the laboratory and thus become accessible to non-specialist users. 🧬Fraunhofer IPMS is developing photonic label-free biosensors based on silicon nitride microring resonators in silicon technology. They are used for the selective detection of biomarkers or microbial substances and offer, for example, a suitable detection method for the early detection of diseases. 🔍💡 In collaboration with Fraunhofer IZI and Fraunhofer IOF we are currently developing a highly sensitive integrated photonic biosensor platform. Learn more on site or on our website: https://lnkd.in/evMjVZcF 👩💼👨💼 For you on site: Jan Grahmann, Thilo Sandner, Peter Dürr, Florenta Costache, Michael Scholles, Heinrich Grüger and Sara Francés #Biosensors #SensorTechnology #Biotechnology #Bioelectronics #MedicalDevices #SensingTechnology #HealthTech

📚 “On the compatibility of single-cell microcarriers (nanovials) with microfluidic impedance cytometry” Cristian Brandi, Adele De Ninno,Filippo Ruggiero,Emanuele Limit,Franca Abbruzzese, Marcella Trombetta, Alberto Rainer, Paolo Bisegna, Federica Caselli 🇮🇹 Università di Roma Tor Vergata 🇮🇹 CNR IFN Istituto di Fotonica e Nanotecnologie 🇮🇹 Università Campus Bio-Medico di Roma 🇮🇹 Cnr - Istituto di Nanotecnologia 📌 Lab Chip, 2024 First published 29 Apr 2024 https://lnkd.in/dHGnC2yP #abstract We investigate for the first time the compatibility of nanovials with microfluidic #impedance #cytometry (MIC). Nanovials are suspendable crescent-shaped single-cell microcarriers that enable specific cell adhesion, the creation of compartments for undisturbed cell growth and secretion, as well as protection against wall shear stress. MIC is a label-free single-cell technique that characterizes flowing cells based on their electrical fingerprints and it is especially targeted to cells that are naturally in suspension. Combining nanovial technology with MIC is intriguing as it would represent a robust framework for the electrical analysis of single adherent cells at high throughput. Here, as a proof-of-concept, we report the MIC analysis of mesenchymal stromal cells loaded in nanovials. The electrical analysis is supported by numerical simulations and validated by means of optical analysis. We demonstrate that the electrical diameter can discriminate among free cells, empty nanovials, cell-loaded nanovials, and clusters, thus grounding the foundation for the use of nanovials in MIC. Furthermore, we investigate the potentiality of MIC to assess the electrical phenotype of cells loaded in nanovials and we draw directions for future studies. 📌 Il lavoro si inserisce nell’ambito del progetto #PRIN2022 MIC-AIM ed è stato inserito nella themed collection “Lab on a Chip Emerging Investigators”

👉 Meet our next partner: Laserlab-Europe AISBL is an international not-for-profit association, bringing together 47 leading laser research infrastructures in 22 European countries. Jointly, they are committed to coordinate their operation and R&D efforts in order to facilitate the development of advanced lasers and laser-based technologies, and to promote the efficient utilization of advanced laser facilities by users from academia and industry. Scientists from all over the world use the facilities to perform experiments in a large variety of inter-disciplinary research, covering advanced laser science and applications in most domains of research and technology. 💡 Six partners from five different countries have joined forces in fastMOT to develop an ultra-high performance light sensor in different imaging techniques to radically improve the performance of #microscopy and #imaging. ➡ Check them out on our partners page: https://lnkd.in/eBnRaXJ6

What's one specific way you've seen virtual reality technology enhance biomedical engineering practices? Submit your answer to this question on Featured, and get featured on BiomedicalEngineering.io: https://lnkd.in/gzufaWBT Deadline: 2024-Apr-23 #Biomedical #BiomedicalEngineering #BiomedicalEngineer

🎯 Nanovials on the Cover 🎯 Congratulations to the Caselli lab (Cristian Brandi) and colleagues in Rome for making the front cover in the latest edition of the Lab on a Chip journal. Key highlights from the publication: 📌 Discover why Microfluidic Impedance Cytometry (MIC) is a valuable tool for characterizing cells. It eliminates the need for fluorescent and chemical labels, enabling real-time monitoring of cells in their natural state. 📌 Explore the compatibility of Nanovials with MIC devices—how electrical properties can be used to distinguish cell-loaded Nanovials. 📸 Check out the stunning images they captured too! 📸 📌 Understand how the properties of cells on Nanovials can be interrogated using MIC. 👉🏽 This publication showcases the synergy of these powerful tools for high-throughput cell characterization. Read the publication here: https://lnkd.in/gt3Z5j6b https://lnkd.in/g3yKhmC4 #Nanovials #technologydevelopment #cytometry #innovation #singlecell

🌟 Highlights from art photonics GmbH at analytica 2024! 🌟 We were delighted to return to #Analytica this year, where we showcased our cutting-edge advancements in live spectroscopy. Unlike traditional methods that rely on static samples, our fiber optic bridges enabled real-time, in-line, in-vivo, and in-situ monitoring across all spectroscopy methods 🧪🔬. At Analytica 24, we were proud to show our progress with multi-spectral systems that are leading the field. From #Raman to #FTIR and #NIR, our technologies allowed chemists to observe reactions remotely from start to finish, revealing every detail of the process as it unfolded. 🎉 This year was particularly significant as we recently joined the Nynomic AG and started our collaboration with our partner NLIR to integrate state-of-the-art spectrometers from NLIR with our Fiber Probes. This enable spectroscopy to become faster and more sensitive, and when paired with our probes, it was capable of capturing every nuance of a reaction in real time. 💡 We also introduced our latest innovation, the #Combi Fiber Probe, which combines multiple #spectroscopy methods at a single tip (Raman+NIR, Mid-IR+Raman), offering unprecedented accuracy and detail in every analysis. Whether examining tissues or liquids - for medical or industrial purposes, our technology promised to revolutionize spectroscopic measurements. 🔍 For more details or custom solutions, visit our website or contact us directly. Let's continue exploring the future of spectroscopy together! #Analytica2024 #Spectroscopy #Innovation #ArtPhotonics #ScienceAndTechnology

 #Nanomotion is expanding its impact in the life sciences and healthcare sectors, leveraging our success in microscopy to embrace wider applications. #Nanomotion collaborated with Optics 11, leading to the creation of the life science analytical tool, a revolutionary biological instrument that advances laboratory capabilities in developing treatments and cures. The life science analytical tool is an automated platform designed for high-throughput reliability, offering unparalleled mechanobiology insights for research advancements. It supports a wide range of applications, from wound healing to tissue regeneration, making it a versatile tool for modern laboratories. Central to the life science analytical tool functionality are four axes of #Nanomotion's precision motion technology, including closed-loop XY stages with sub-micrometer accuracy and a Z stage featuring a 29 mm travel range and 2.5 nm resolution. This enables precise measurements across various sample sizes, from small-scale features to larger specimens. Through the life science analytical tool, #Nanomotion is not just contributing to the life sciences and healthcare industries, we're transforming them by enabling more precise, efficient, and innovative research methodologies. To stay informed about the latest developments in the life sciences and healthcare sectors, click here to read our newsletter >>>> https://lnkd.in/dr4TRv_A

Global Bio Optics Market size was valued at USD 1.8 Bn. in 2022 and the total Bio Optics revenue is expected to grow by 6.3 % from 2023 to 2029, reaching nearly USD 2.8 Bn. Click here for free sample + related graphs of the report: https://lnkd.in/dbGygNUp The Bio Optics Market is rapidly advancing as cutting-edge technologies revolutionize medical diagnostics, life sciences research, and environmental monitoring. With applications ranging from high-resolution imaging to non-invasive diagnostics, bio-optics plays a pivotal role in enhancing our understanding of biological processes at the molecular level. As the demand for precision medicine and personalized healthcare grows, the bio-optics market is poised for significant expansion, driven by innovations in optical systems, sensors, and imaging techniques. #BioOptics #HealthcareInnovation #MedicalImaging #LifeSciences #PrecisionMedicine

New Evos M3000 !!! Simplify your cell culture workflow with automated, unbiased confluency measurements 🔬 Introducing the EVOS M3000 Imaging System - the ideal solution for your cell culture lab. It will report confluency percentage seen in the field of view in seconds without requiring any image capture - helping to eliminate user bias in routine cell culture🧫. 💡 Looking to add fluorescence capabilities to your imaging system? The EVOS M3000 Imaging System offers the flexibility to upgrade to fluorescence imaging whenever you need it. Simply add the EVOS LED Light Cubes. Make this compact, upgradeable, easy-to-use system your go-to manual microscope. https://lnkd.in/gU7z9Vby #Invitrogen #EVOSM3000 #ImagingSystem #Microscopy #Imaging #LiveCellImaging #CellAnalysis #ResearchEfficiency #Research #Innovation #ScientificAdvancements