Association for Molecular Pathology (AMP)’s Post

Sulfonamide antibiotics function effectively against gram-positive and certain gram-negative bacteria. Sulfonamide antibiotics function by competing with p-aminobenzoic acid (PABA) during the synthesis of folic acid which is essential for DNA replication, which inhibits bacterial DNA growth and cell division or replication. #IVD #artron #bioartron #Sulfonamides #antimicrobial  #syntheticantimicrobialdrug #antibioticdrug #bacterialinfection #Sulfonamidestest #Sulfonamidesrapidtest

🍻 Published in Science: PtpB, a known protein phosphatase secreted by Mycobacterium tuberculosis, acts as a phospholipid phosphatase that dephosphorylates host plasma membrane phosphoinositides upon activation by ubiquitin to inhibit pyroptosis. Furthermore, PtpB suppressed the secretion of IL-1β and IL-18, two vital inflammatory cytokines released by macrophages upon inflammasome activation in a GSDMD-dependent manner 👉 Related Product Recommendation: IL-18BP Protein, Mouse (HEK293, His): https://lnkd.in/gjXj5_Th 👉 For more detailed information: https://lnkd.in/gYn8CExV

DNA Ladders, also known molecular-weight size markers, contain a set of predetermined DNA fragment sizes. These markers are a set of standards used to identify the approximate size of a DNA fragment run on gel electrophoresis. #DNAladder #DNA #markers #DNAfragments #genes #genetics #genome #genomicsforhealth #genomicsforall #genomicsforlife #MiBiome #MiBiomeTherapeutics

#MDPIAwardWinners 📢 One of the winners of Pathogens 2024 Best Paper Award: "Methods of #Inactivation of Highly Pathogenic #Viruses for Molecular, Serology or Vaccine Development Purposes" 👨🎓 by Simon Elveborg, Vanessa M. Monteil, and Ali Mirazimi 👉 Free download available: https://lnkd.in/gCiQSYyY This article reviews available inactivation techniques published in peer-reviewed journals and their benefits and limitations in relation to the intended application. #SARSCoV2

Did you know that Monocytes are part of the first lines of defense of our immune system engulfing foreign antigens and cell debris? Edible Aphanizomenon flos-aquae has monocyte activating properties. "Characterization of human monocyte activation by a water soluble preparation of Aphanizomenon flos-aquae" https://lnkd.in/dKPUZZ9s

Metagenomic shotgun sequencing reveals the enrichment of Salmonella and Mycobacterium in larynx due to prolonged ethanol exposure. Read the article here: https://lnkd.in/gQhcF9_Q

SIMPLIFY #pointofcare genetic testing with the Genedrive® CYP2C19 ID Kit! 1. Take a buccal cell sample using a non-invasive cheek swab. 2. Mix the sample with the lysis buffer to stabilise the sample and prepare it for genetic testing. 3. Use the pipette to transfer the sample into the cartridge. 4. Wait 60 seconds to allow the dried reagents inside the cartridge to reconstitute. 5. Insert the cartridge into the Genedrive® System and press Start Test on the touch screen. #GDR

How do germ line cells keep not only young but immortal as soma in every generation die of old age ? One clue is protein turn over in the oocyte https://lnkd.in/eh3AaE2y

#genetics #medicine #medicalscience Exome All known protein-coding sequences, or #exons, in the human #genome, constituting approximately 1 to 2% of the 3.2 billion nucleotide base pairs in the human genome.

Do you find challenging to remove HcDNA and chromatin stuck with AAV capsids after cell lysis? In this webinar @Sarah Lechat and @Dmitry Zabezhinsky explain how Benzonase® Salt Tolerant Endonuclease was developed to remove residual host cell and plasmid DNA under high salt lysis conditions where classical endonuclease enzymes are inactive. Join them to move your AAV process to the next level. Save your seat today.