Babraham Research Campus’ Post

🧬 𝐉𝐨𝐢𝐧 𝐔𝐬 𝐟𝐨𝐫 𝐚𝐧 𝐈𝐧𝐬𝐩𝐢𝐫𝐢𝐧𝐠 𝐖𝐞𝐛𝐢𝐧𝐚𝐫 𝐰𝐢𝐭𝐡 𝐏𝐫𝐨𝐟. 𝐒𝐡𝐢𝐱𝐢𝐧 𝐋𝐢𝐮! I’m thrilled to share that on December 3rd, we’ll be hosting Prof. Shixin Liu from The Rockefeller University for a webinar that promises to be as insightful as it is inspiring. Prof. Liu’s lab has been transformative in how they leverage the C-Trap to unravel the complexities of DNA replication and chromatin organization. He has also published some of the most elegant and impactful papers showcasing the power of the C-Trap in groundbreaking research. 🔬 𝐖𝐡𝐚𝐭 𝐭𝐨 𝐄𝐱𝐩𝐞𝐜𝐭 𝐃𝐮𝐫𝐢𝐧𝐠 𝐭𝐡𝐞 𝐖𝐞𝐛𝐢𝐧𝐚𝐫: 🌟 Gain insights from his latest landmark publications including: - How 𝐌𝐄𝐂𝐏𝟐 𝐦𝐮𝐭𝐚𝐭𝐢𝐨𝐧𝐬 affect DNA binding - The role of 𝐥𝐢𝐧𝐤𝐞𝐫 𝐇𝐢𝐬𝐭𝐨𝐧𝐞 𝐇𝟏 in phase separation - Visualization of the 𝐝𝐲𝐧𝐚𝐦𝐢𝐜 𝐛𝐞𝐡𝐚𝐯𝐢𝐨𝐫 𝐨𝐟 𝐂𝐌𝐆 𝐡𝐞𝐥𝐢𝐜𝐚𝐬𝐞 at the replication fork 🌟 Discover how the 𝐂-𝐓𝐫𝐚𝐩 has enables some of his lab's most groundbreaking discoveries 🌟 Learn how 𝐬𝐢𝐧𝐠𝐥𝐞-𝐦𝐨𝐥𝐞𝐜𝐮𝐥𝐞 𝐭𝐞𝐜𝐡𝐧𝐨𝐥𝐨𝐠𝐲 is transforming research in DNA replication and chromatin organization. Whether you’re a PI, postdoc, or simply curious about single-molecule research, this is a must-attend event to explore the science behind transformative breakthroughs. 📅 𝐒𝐚𝐯𝐞 𝐭𝐡𝐞 𝐃𝐚𝐭𝐞: December 3rd 🔗 𝐑𝐞𝐠𝐢𝐬𝐭𝐞𝐫 𝐇𝐞𝐫𝐞: https://lnkd.in/e8s5T-qT

As professionals in the field of science and technology, we are always on the lookout for groundbreaking discoveries that can change our understanding of the world. Recently, a fascinating finding has been made in the realm of cellular biology, and it's got everyone in the scientific community buzzing 🌟. The discovery revolves around the natural process of endosomal tether collapse, which brings vesicles together in cells. This phenomenon has significant implications for our understanding of cellular function and behavior. By studying how vesicles interact and merge, scientists can gain valuable insights into the intricacies of cellular processes, such as protein transport and cell signaling 📢. The potential applications of this research are vast, ranging from the development of new therapeutic strategies to a deeper understanding of cellular mechanics. As we continue to unravel the mysteries of cellular biology, we may uncover new and innovative ways to address some of the world's most pressing health challenges. The full story behind this exciting discovery is a must-read for anyone interested in the latest advancements in cellular biology 📚. To learn more about the endosomal tether collapse and its implications, be sure to check out the full article at https://lnkd.in/drHGeTNx

A big thank you to DeciBio for featuring our Chief Commercial Officer, Aneesh Acharya, PhD, in their latest blog post! From advancing drug development to bridging gaps in diagnostics, Aneesh shares valuable insights into the evolving bioimaging landscape. Dive into the interview to learn more about how these innovations are shaping the future of healthcare #onlywithHCR: https://lnkd.in/g_fm2Dn9

Exploring Advances in Spatial Biology In our latest blog post, Rebecca Burnham, PhD and Nila Venkat sit down with Aneesh Acharya, PhD, Chief Commercial Officer at Molecular Instruments, to discuss the evolving landscape of bioimaging and its applications in research and clinical settings. With a background in synthetic biology and molecular programming, Aneesh offers a unique perspective on how advancements in spatial biology are shaping the future of precision medicine. Key topics include: - The growing role of spatial biology in early drug development - The challenges and opportunities for integrating spatial techniques into clinical diagnostics - How the needs of academic and biopharma users differ when it comes to adopting new technologies - The potential for spatial biology to address gaps in diagnostics, particularly in areas where traditional methods fall short Read the full interview to learn more about how spatial biology is driving innovation in precision medicine: https://lnkd.in/g_fm2Dn9 #precisionmedicine #spatialbiology

Big news. MIT Jameel Clinic’s Boltz-1 is challenging the Nobel Prize winners on the very foundations of biomolecular research. Boltz-1 achieves AlphaFold3-level accuracy in predicting biomolecular interactions. Boltz-1 matches or exceeds AlphaFold3 in key metrics like structural accuracy in biomolecular predictions (Mean LDDT-PLI) and binding interaction reliability (DockQ > 0.23). It is the first fully open-source model of its kind with model weights, training code, and datasets are accessible under the MIT license. Boltz-1 democratizes tools traditionally locked behind closed doors, paving the way for breakthroughs in drug discovery and precision medicine. Check out the Github repo: https://lnkd.in/gk38M2Un

🌟 Highlights from the First CLT Meet of 2025! 🌟 On January 17, 2025, the Centre for Living Technologies hosted the first CLT Meet of the year at the Alliance Office, Utrecht University. This event brought together researchers from synthetic and molecular biology to exchange ideas and showcase advancements in living technologies. Key topics covered included: - The Utrecht Platform for Organoid Technology (UPORT): Advancing organoid research and applications. - Engineering of thermophiles: Innovations for the production of bio-commodities. - A synthetic biology approach to decode extracellular vesicle-mediated signaling in vivo: Unlocking the potential of cellular communication. - Molecular deep learning at the edge of chemical space: Exploring the boundaries of computational chemistry. We are incredibly grateful to our brilliant speakers for sharing their expertise and to the attendees for their enthusiasm and engagement. Your contributions made this event truly inspiring! 📌 CLT Meets will now be held three times a year! The next meet is scheduled for May 2025—stay tuned for the official dates and more details.

🌟 Thrilled to Announce My New Publication! 🌟 I am excited to share my original article titled: “Significance of 260/230 Ratio and Strategies for Optimized and Improved PCR Outcome” 🔗 https://lnkd.in/gpKqEFB3 This research explores the critical role of DNA purity and integrity as quality indicators for biomedical research, particularly in ensuring reliable downstream applications like PCR. Key highlights include: • Quality assessment of DNA from 12 blood samples. • Optimization strategies to improve outcomes from low-quality DNA samples. • Emphasis on robust DNA quantification and qualification techniques for effective sample management, reducing costs, and minimizing errors. The findings aim to contribute to better practices in DNA sample preparation and pave the way for more reliable research outcomes. Looking forward to your thoughts and feedback! #ResearchPublication #DNAQuality #BiomedicalResearch #PCROptimization #ScientificBreakthroughs

Exciting webinar coming up at BioCogniz! Learn about the latest advancements in studying molecular interactions through coarse-grained simulations!

A National Science Foundation (NSF) National Synthesis Center for Emergence in the Molecular and Cellular Sciences at Huck Institutes of the Life Sciences recently celebrated its ribbon-cutting. Research done in the center could eventually inform the development of disease treatments and other applications, such as minimizing the negative effects of aging.

We’re proud to announce our new partnership with The Company of Biologists. This collaboration integrates publications from their top journals into our AI-powered platform, ASCEND, giving scientists streamlined access to vital research including open and closed-access publications. Today, most scientists rely on the world’s scientific findings to advance scientific discovery. However, the increasing volume of research (over 1.5 million new articles annually) makes extracting up-to-date and reliable information a significant challenge. This often leads to unnecessary experimental errors and missed research opportunities. This partnership addresses this key challenge and empowers scientists with greater access to documented research, accelerating their work in drug discovery. Learn more about our partnership with The Company of Biologists and how we're empowering scientists across preclinical R&D:  https://lnkd.in/eiAg5JDz