Benjamin Hassanzadeh’s Post

Klotho, an antiaging protein, has been shown to have multiple beneficial actions on various targets, making it a promising candidate for translational medicine. It is proposed in this interesting article as a valuable marker in the emerging field of lifestyle medicine. Incorporating Klotho as a routinely requested biological marker, especially in the prevention and evolution control of age-associated diseases, does not seem unsupported. #AntiAging #TranslationalMedicine #LifestyleMedicine #BiologicalMarkers

DOES INCREASED POTASSIUM IN OUR DIET INFLUENCE HORMONE-RELATED DISEASES? Postdoc Mariavittoria D'Acierno from the Department of Biomedicine receives DKK 1.2 million from the Danish Diabetes and Endocrine Academy (DDEA) towards her research into hormone-related diseases such as diabetes. The grant will fund her two-year postdoc programme. In her research project, Mariavittoria d'Acierno will examine the consequences of increased potassium in the diet for bone and skeletal problems, cardiovascular health, and diabetes.   Current research indicates that Western dietary habits are a significant cause of high blood pressure. While high salt intake is a major trigger, research shows that a lack of potassium in the diet also plays a major role in high blood pressure. Many people with high blood pressure also have bone and skeletal problems such as osteoporosis. This could indicate that the mechanisms that modulate blood pressure also regulate bone mineralisation, and that increased potassium intake may be an inexpensive and effective mechanism to lower blood pressure, for example. 👏🏼 Congratulations on your grant, Mariavittoria d'Acierno – and the best of luck with your postdoc programme! 👉🏼 Read the full story at the faculty website: https://lnkd.in/dDymP_54   📸: Danish Diabetes and Endocrine Academy.   Aarhus University | Robert Fenton #healthau #DDEA #research #biomedicine #diabetes

Advanced Novel Bio-Microbiomic Scores => #Microbiome_Based_Diagnostic_Tools #Microbiome_Based_Therapeutic_Tools

Are you familiar with grounding or "earthing?" 🌎 🌊 ⛰ 👣 Earthing can be thought of as connecting your body to the Earth's gigantic electromagnetic battery. For example, when you walk barefoot on the grass, or sand at the beach and soak up all of that beautiful, grounding energy. Incredibly enough, studies have shown there are proven scientific benefits of earthing that go beyond just feel good chemicals! 💡 Regulation of Physiological Processes: Earthing influences various physiological processes, including calcium-phosphate homeostasis, thyroid function, and glucose concentration. It helps maintain the balance of essential elements and hormones in the body, potentially improving overall health. 📈 Managing Blood Glucose Levels: Continuous earthing of the human body has been shown to decrease blood glucose levels in patients with diabetes. This suggests that earthing could have potential benefits for managing blood sugar levels and diabetes. 😌 Decreased Inflammation: Earthing influences various physiological processes, including potentially decreasing inflammation. This is significant, as inflammation is associated with numerous chronic health conditions, and reducing it can lead to improved health outcomes. Check out the study below! ⬇ https://lnkd.in/ecthMKwj

🌟 Changing the Frontier of Precision Medicine & Metabolic Health! 🌟 Let's dive into a ground breaking realm of healthcare that's set to revolutionize the way we understand and treat metabolic dysfunction. 🚀 🔍 What is Metabolic Dysfunction? Metabolic dysfunction is a complex condition characterized by an imbalance in our body's metabolism - the process by which our bodies convert what we eat and drink into energy. When this system is out of balance, it can lead to a myriad of health issues, including type 2 diabetes, cardiovascular diseases, obesity, metabolic liver diseases, and even increasing the risk of certain cancers and neurodegenerative diseases like Alzheimer’s. 🧬 The Rise of Omics Testing: Beyond Genomics For years, genomics has been at the forefront of personalized medicine, offering insights into our genetic blueprint. But now, we're entering an even more exciting phase - the era of metabolomics! 🌈 Metabolomics offers a dynamic view of how our genes interact with our environment, diet, lifestyle, and even the microbiome in our gut. By analysing thousands of metabolites, we can now obtain a detailed metabolic phenotype. This breakthrough allows us to see how our metabolism actually functions and identifies ways it can be optimized. Imagine tailoring your diet, lifestyle, and treatments based on a comprehensive analysis of your metabolism. 💡 Why Does This Matter? Metabolic dysfunction, if left unchecked, paves the way for chronic diseases that diminish our quality of life and shorten our health span. However, with the advent of metabolomics, we have a powerful tool to personalise treatment plans and to prevent these diseases before they take root. 🚀 A New Era of Healthcare Just as precision medicine has revolutionized oncology and reproductive health, we are now poised to make significant strides in combating metabolic diseases. At Ultra BiOmics, we are integrating these innovative omics technologies to transform healthcare. Our vision is a future where health is personal; to harness the power of omics to offer personalized, precise treatments that not only address metabolic dysfunction but also enhance overall metabolic health. 🌱 💪 Join us in embracing this new era of healthcare innovation. Together, we can pave the way for a healthier, brighter future for all. #PrecisionMedicine #Metabolomics #MetabolicHealth #Innovation #Healthcare #UltraBiOmics #FutureOfHealth 👉 Stay tuned for more updates and feel free to reach out to learn how you can be a part of this health revolution!

Natural compounds in gut microbiome show promise for inflammation treatment Researchers at the University of Toronto have discovered naturally occurring compounds in the gut microbiome that can potentially treat inflammation. These compounds interact with the constitutive androstane receptor (CAR), which plays a key role in processing foreign substances and managing inflammation in the liver. The study identified two specific compounds, diindolylmethane (DIM) and diindolylethane (DIE), which regulate CAR without the side effects associated with synthetic compounds, such as liver enlargement. These findings suggest a promising new approach to treating conditions like diabetes, fatty liver disease, and ulcerative colitis using components already present in the human gut. This research not only provides insights into new treatments but also underlines the significant role of gut-produced compounds in health management. Link to Study: https://lnkd.in/dzTpgbsX #microbiome #functionalnutrition #inflammation #guthealth #guthealthmatters #metabolichealth

#newresearchupdates Chatting with with our Academy patient cohort about health literacy and research updates and we have chosen this article to study to profile and assist patients in understanding longevity and human performance. The focus of this exciting article of research with an exercise physiology base was short term supplementation with a selective essential amino acid (EAA) formulation may reduce liver fat and aspartate aminotransferase (AST) and plasma triglyceride concentrations in adolescent girls with polycystic ovary syndrome (PCOS) and obesity. #healthliteracy and #healthempowerment is essential to #closethegap #longevity #exceptionalhumanperformance Research in science is important and helps us to progress and achieve longevity but also understanding limitations and its applications is important too and empowering patients is key to their longevity. Empowering patients with the correct #healthinformation is important and how it relates to your individual body and biochemistry is what matters we are all unique #understandingevidencebasedmedicine #AIforhumanity #spacemedicineresearch https://lnkd.in/ggw4AMmp

A study by Melina Rojas-Criollo, Mònica Bulló, et al. has revealed the mechanism behind the link between a diet high in saturated fats and #AlzheimersDisease. The research focused on how this kind of diet affects certain molecules found in the blood and in other tissues such as the brain that act as markers and regulators of the disease. These molecular changes correlate with early onset #Alzheimers, providing insights into the connections between #Diet, #Obesity, type 2 #Diabetes, and #NeurodegenerativeDiseases. The findings offer potential new targets for preventing and treating Alzheimer’s. Learn More in MDPI | Nutrients https://lnkd.in/etYEMrxK Effects of a High-Fat Diet on Insulin-Related miRNAs in Plasma and Brain Tissue in APPSwe/PS1dE9 and Wild-Type C57BL/6J Mice - Melina Rojas Criollo, Nil Novau Ferré, Laia Gutierrez Tordera, Miren Ettcheto, Jaume Folch, Christopher Papandreou, Laura Panisello, Amanda Cano, Hamza Mostafa, Javier Mateu Fabregat, Marina Carrasco, Antoni Camins and Mònica Bulló Universitat Rovira i Virgili (URV) Institut d’Investigació Sanitària Pere Virgili - IISPV Universitat de Barcelona Carlos III Health Institute CIBERNED - Centro de Investigación Biomédica en Red Universitat Internacional de Catalunya Human Nutrition Unit - (URV-IISPV-CIBERobn)

Do microbes in our saliva and gut influence our overall health and wellness 🤔 ? Exploring the "oral-gut" axis in an interesting coffee session with Dr Andrea Lorena Basualdo Allende . . What is the "oral-gut" axis? The term "oral-gut axis" refers to the bidirectional communication between the oral cavity and the gastrointestinal tract. In a recent study, researchers set out to unravel the mysteries of the oral-gut axis by characterizing and comparing the salivary and faecal microbiota of individuals with Inflammatory Bowel Disease (IBD) and those without the condition. One of the significant findings was the identification of a distinctive signature in the salivary microbiome of IBD patients! This sheds light on the intricate relationship between oral and gut health. Key findings 💡: The study revealed a distinct microbial composition in the saliva of IBD patients compared to control subjects! Notably, IBD patients exhibited a high abundance of the genera Prevotella sp. and Veillonella sp., while experiencing a depletion of salivary genera associated with a healthy gut, such as Streptococcus, Haemophilus, and Neisseria. Is there a link 🔗 between #oral #microbiota and #systemic #diseases? Interestingly, an increased abundance of Prevotella and Veillonella in the oral cavity has been associated with not only periodontitis but also systemic diseases such as #rheumatoidarthritis, lung diseases, oesophagal conditions and even #colorectalcancer! This suggests a broader role for the oral-gut axis in influencing our overall health and well-being. My #perspective : As #clinicians, #dentists, #biotechnologists, #scientists and #entrepreneurs it is time that we come together in a more integrated way rather than talking in discrete specialities. It is crucial to understand the intricate relationship between the oral and gut microbiota to unravel the complexities of chronic diseases like IBD. Afterall, everything inside our body is interconnected! Exploring the oral-gut axis will serve as a fascinating avenue for exploring future advancements in #preventive and #therapeutic #interventions. What do you think #linkedinfamily? Post inspiration: Check the link in comments

Guiding much of modern medicine is the “germ theory” of disease—a framework that led to the development of the first antibiotics in the 1940s. Though credited with saving millions from deadly infections, the current explosion in chronic conditions highlights its shortfalls. Proposed around the same time, the nearly forgotten model of “terrain theory” is finally getting the attention it deserves, and may come to dominate the next evolution in medicine. As an individual, you can embrace the principles of terrain theory to reverse disease and keep you healthy. While germ theory proposes that illness is the result of a specific germ and that only destroying the germs will make us well, terrain theory postulates that a weakened body attracts disease while a healthy body resists it. The two theories are often compared using the analogy of a fish tank. If your fish is sick, germ theory would indicate you should isolate the fish and perhaps add some antibiotics or a vaccine. Terrain theory says, “Clean the tank!” Our bodies are our terrain. Keeping our terrain healthy includes feeding it nutritious food free of toxins, exercising our muscles through regular movement, enabling it to rest and repair through adequate sleep, and keeping our minds and souls energized through positive social interactions. However, the principles of terrain theory do more than keep us healthy. They can be used to restore us to health once sick. Whereas focusing only on a single cause such as a pathogen lends itself well to a business model supporting pharmaceuticals, a holistic approach to health underpinned by the terrain theory emphasizes lifestyle and puts the solution largely in our own hands. https://lnkd.in/gh72TH-6