BIOKÉ’s Post

#CancerResearch antibodies help map altered pathways in tumor cells, leading to new diagnostic markers and treatment targets. As you unravel cancer's metabolic secrets, quality antibodies remain key to discoveries. View our catalog here: https://lnkd.in/eubmmk9P #research #biotech #phdlife

Genialis UPDATE 🔊:  A first-in-class, RNA-based biomarker that will transform #KRAS G12C inhibitor response stratification in #NSCLC patients will be launched at #AACR. Curious about efficacy? DM me. #precisionmedicine #RNA #cancer #oncology #AI #machinelearning #clinicaldevelopment #clinicaltrials #drugdevelopment #precisiononcology

Every cancer is unique, requiring precise models for effective treatment development. Our solution? #Rastrum provides the tools to model complex biology in your cancer research: 🔬 Replicate Microenvironments: Customize conditions to mimic specific tissue and cellular environments, aiding in the study of cancer cell behaviors. 🔬 Enhance Drug Discovery: Investigate tumor development and cancer progression for more effective drug development. 🔬 Improve Predictability: Achieve results that closely match in vivo conditions for greater reliability and clinical relevance. 🔬 User-Friendly: An intuitive interface and efficient workflows integrate seamlessly into your processes, saving time and resources. Drive therapeutic advancements, model interactions and more with Rastrum: https://lnkd.in/g2S2CQdv

Tackle your spatial transcriptomics challenges head-on with Indivumed Services' webinar on June 12 and enhance your biomarker discovery processes. Dr. Nicole Kerstedt will detail how advanced platforms can streamline your research and provide insights into the transcriptional landscape within the histological context of tumor tissues. This educational session will empower you with the knowledge needed to make informed decisions on drug treatment and pathway interactions, taking your cancer research and therapeutic strategies to the next level. Don't miss out on this opportunity to transform your research! https://hubs.la/Q02zCV0g0 #Biomarkers #SpatialTranscriptomics #DrugProfiling

Summary: The study explores a novel approach in cancer immunotherapy by utilizing a controlled release system to deliver manganese and magnesium ions to modulate the tumor microenvironment and enhance T cell activation. The staged release of these ions showed promising results in reshaping the tumor immune microenvironment and improving the efficacy of immune checkpoint blockade therapy in preclinical experiments. Hashtags: #CancerImmunotherapy #MetallicIons #TumorMicroenvironment #DrugDelivery #Biohacking Read more here: https://lnkd.in/eeWhwgt7 BioMedHack.com is your leading source for the latest news, breakthroughs, and insights in medicine, biohacking, and alternative medicine. Our mission is to help you live healthier and longer by bringing you cutting-edge information and expert advice. Follow us on Facebook, Instagram, and X.

🚨 Last chance to register! Join us on June 12 for an exclusive webinar tackling your spatial transcriptomics challenges and enhancing your biomarker discovery processes. https://hubs.la/Q02zZ0ht0 Dr. Nicole Kerstedt will share insights on advanced platforms that streamline research and reveal the transcriptional landscape within tumor tissues. This session will equip you with the knowledge to make informed decisions on drug treatment and pathway interactions, elevating your cancer research and therapeutic strategies. Don't miss out on this opportunity to transform your research! #Biomarkers #SpatialTranscriptomics #CancerResearch #DrugDiscovery

Evolution of CAR-T Cells: From First to Fifth Generation CAR-T cell technology has evolved significantly since its inception. Here’s a look at the progression through its generations: 1. First Generation: Early CAR-T cells had limited efficacy and persistence due to the use of a single activation domain. 2. Second Generation: Addition of costimulatory domains (CD28 or 4-1BB) improved their survival and anti-tumor activity. 3. Third Generation: Combined multiple costimulatory domains, further enhancing functionality and longevity. 4. Fourth Generation (TRUCKs): Incorporated inducible cytokine production, improving the ability to modulate the tumor environment and activate innate immunity. 5. Fifth Generation: Introduced IL-2 receptor chains and advanced signaling pathways, enhancing CAR-T cell persistence and reducing the risk of exhaustion. These advancements have progressively improved the efficacy and safety of CAR-T therapies, making them more robust and effective. #CAR-T #Biotech #CancerResearch #Cancer #Therapy #Science #Medicine

DNA and RNA from FFPE matched sets allow clinicians to answer important questions such as: 📌Why did this treatment work for this patient and not another? 📌Why did the patient develop resistance after two months? 📌What mutations or transcriptome changes were associated with that resistance? FFPE slides for IHC allow clinicians to monitor immune cell infiltration which is important for treatment efficacy in cancer. Accelerate your drug discovery and diagnostic development with our FFPE matched sets.  ✅ Speak to our scientific team today - https://lnkd.in/dFtD8bBS #ffpe #tissues #biospecimen #biobanking #matchedffpesets

Exosomes, those tiny (30-150 nm) extracellular vesicles released by cells through exocytosis, are revolutionizing the field of cell-to-cell communication. These incredible messengers deliver genetic and bioactive molecules to target cells, holding immense potential for novel diagnostic and treatment strategies, especially in the realm of cancer. Learn more about them and how they can help transform your diagnosis and treatment strategies: https://lnkd.in/ePK7xwq3

Harness the power of hydrogels in localized cancer treatment by exploring their ability to encapsulate and deliver therapeutic agents efficiently. The unique properties of hydrogels, such as controlled release and biocompatibility, make them promising platforms to enhance the efficacy of immunotherapy for breast cancer while minimizing side effects. Consider incorporating hydrogel-based delivery systems in cancer treatment strategies to improve outcomes and patient well-being. #HydrogelTherapeutics #CancerTreatmentInnovation #ImmunotherapyAdvancements #LocalizedTherapy #BiocompatiblePlatforms BioMedHack.com is your leading source for the latest news, breakthroughs, and insights in medicine, biohacking, and alternative medicine. Our mission is to help you live healthier and longer by bringing you cutting-edge information and expert advice. Follow us on Facebook, Instagram, and X. Read more about this post here: https://lnkd.in/e3JxcTdk