Bionl.ai’s Post

During the 2024 #AACR Annual Meeting this week, the concept of #metastasis has dramatically changed since its last plenary session 14 years ago.... David Lyden's session on "Evolution of the Genome, Microenvironment, and Host through Metastasis" reveals new insights on the importance of tumor-secreted factors and extracellular vesicles (EVPs) which can have downstream effect on different organs and can contribute towards a systemic effect. As Lyden's team discovered, EVPs as a result of a pancreatic tumor can disrupt the liver's function, increase the side effects of chemotherapy and even increase the likelihood of metastases outside the liver. Said differently, “if you have cancer going to the lung, you can’t ignore that you have a fatty liver as well.” The evolving understanding of metastasis emphasizes the need for a more comprehensive approach to cancer research and treatment. To learn more about his work and conference insights, continue reading here: https://lnkd.in/g_XJB3ed #Pharmaceutical #Biotech #Diagnoses #Medicine #Clinical #Healthcare #Lifescience #CancerResearch #CancerTreatment #CancerCells #Oncology #MedicalResearch #Healthcare #CancerAwareness #CancerBiology #InnovationInMedicine #HealthcareIndustry #CancerPrevention #CancerScience #HealthScience #MedicalCommunity #CancerEducation

RNA seq data analysis using DESeq2 tutorials on R. one of its plots is Volcano plot which shows the downregulated / lower expressed genes and Upregulated/overexpressed genes according to the case and the data you working with. Here is a volcano plot between Normal Solid tissue (control) samples Vs primary Tumor samples of Bladder cancer patients data. #Bioinformatics #DESSeq2 #RNA_analysis #R_analysis #volcano_plot

Patient-derived tumour organoids can be used to predict how effectively patients with bowel cancer will respond to drug treatment, according to a new study. These organoids could allow clinicians to avoid wasting precious treatment time on therapies that won’t work for each individual patient. Barbora Cerna writes about these organoids in BioNews: https://lnkd.in/eadU2MPj Don’t miss out on all the latest news and reviews – subscribe to our free weekly BioNews newsletter here: https://lnkd.in/epXHmM-4 #organoids #tumour #cancer #bowelcancer #personalisedmedicine #genetics #genomics

We are excited to present a collection of application notes featuring data on #KingFisher's automated magnetic bead sample extraction #technology. This cutting-edge method isolates high-quality #DNA, #RNA, #proteins, and cells, driving advancements in #cancer research, #microbiome studies, #viral research, and beyond. Key Highlights: 🧬 Reliable results for cancer biomarker discovery 🌱 Precision in microbiome studies 🦠 Enhanced viral pathogen detection 📊 Explore the application notes and accompanying date here: https://lnkd.in/etN3fdiD

Some interesting data on non-small cell lung cancer (NSCLC) and biomarker testing in the US. Biomarker testing plays a pivotal role in tailoring treatments. By assessing genetic mutations and protein expressions, clinicians can select optimal therapies, emphasizing the critical importance of understanding the biomarker landscape in NSCLC. These insights are derived from Diaceutics DXRX database of de-identified, real-world patient and lab data. Get in touch to learn more about how our data insights can enhance your precision medicine commercialization strategy. #NSCLC #realworlddata #precisionmedicine

Introducing our new Discover DXRX Data Fact Sheet Series! NSCLC constitutes a staggering 85% of all lung cancer cases. In the US, biomarker testing plays a pivotal role in tailoring treatments. By assessing genetic mutations and protein expressions, clinicians can select optimal therapies, emphasizing the critical importance of understanding the biomarker landscape in NSCLC. Join us on this data-driven journey as we explore the exciting world of DXRX data capabilities! Read our latest fact sheet here: https://lnkd.in/eKCjB2yn #PrecisionMedicine #DXRXData #Biomarkers #NSCLC #Realworlddata

🌟 Advancing Technology & Innovation with Genetron Health! 🌟 From scientific breakthroughs to clinical applications, from prevention to treatment, Genetron Health remains committed to making technology simple and efficient in addressing needs across the full cycle of cancer care. 💡 One-Step Seq Method 💡 Our proprietary technology One-Step Seq Method simplifies the complex gene trapping process at the PCR level to offer rapid, stable performance and a low-cost option suitable for independent testing in hospitals. 📹 Watch our video to see the One-Step Seq Method and learn more about its impact on cancer care. #GenetronHealth #Innovation #Genomics #HealthcareTech #Cancer #NGS #Oncology #Molecularprofiling #Laboratorydevelopedtest

Join the Webinar for a great discussion on the advancement of cancer diagnostics for improving patient outcomes through actionable insights. #pharma #oncology #biotech #bigpharma #precisionmedicine

Sign up for the Prognos Health webinar to learn more about personalized medicine and the adoption of targeted therapies for individual cancer patients #personalizedmedicine #oncology #genomicmedicine

Early detection of cancer cells plays an important role in improving curative outcomes in colorectal cancer (CRC) patients, and the noninvasive screening of DNA methylation biomarkers can contribute to successful early CRC detection. In this paper by Li et al. (2023), BioChain’s high quality genomic DNA samples were used as negative references in a combination method approach to evaluating the methylation status of selected CRC biomarkers. Combination methods such as those used by Li and colleagues can enhance the sensitivity of CRC and precancerous lesion detection and improve patient outcomes. Read more here: https://bit.ly/3zDmxgH #cancercells #biomarkers #DNA #samples #biotech