BIOREMIA ETN’s Post

Scientific progress shouldn't be limited by cell line challenges. Our new poster explores how CellRaft® Technology helped six researchers overcome unique obstacles. Get inspired and unlock your research potential! DOWNLOAD POSTER: https://lnkd.in/eH2yZHkK #CellLineDevelopment #CellRaftTechnology #SenescentCells #SingleCellAnalysis #SingleCellTech #CellularHeterogeneity #SingleCellResearch #CellularBiology

📢 Publication Alert! 📢 I'm happy to share that our research paper titled "Investigating Curcuminoid Encapsulation in β-Cyclodextrin: Insights from NMR Spectroscopy and MD Simulations" has been accepted for publication in the prestigious Elsevier #FoodHydrocolloids journal! This work is centered on curcuminoids, value-added products from turmeric, and specifically focuses on understanding the low bioavailability of curcuminoids. By encapsulating curcuminoids with the well-known β-cyclodextrin encapsulation agent, we aimed to enhance their stability, interaction, and effectiveness. The objective of the study was to compare curcuminoids in all three forms (curcumin, demethoxycurcumin, and bisdemethoxycurcumin) and their interactions with β-cyclodextrin. Our study dives deep into the interaction mechanisms and encapsulation strategies using state-of-the-art NMR spectroscopy, supported by molecular dynamics (MD) simulations. I would like to extend my heartfelt thanks to my collaborator, Dr. Santosh, for his invaluable contributions and support throughout this research journey. Stay tuned for more updates and insights from our study! Read the full paper here: https://lnkd.in/gf9ZM__A #Research #Curcuminoids #Turmeric #Encapsulation #Cyclodextrin #NMR #MDSimulations #FoodHydrocolloids #ScientificResearch #Innovation

A great article, co-authored by Olga Tarkhanova and Yurii Moroz, is out!  https://lnkd.in/ehDrCmWp This work is dedicated to exploring AlphaFold2 structures in ligand discovery. The authors have docked large libraries against AF2 models of the α2 and 5-HT2A receptors, testing hundreds of new molecules. Despite differences in orthosteric residue conformations, the result showed high hit rates and affinities similar to experimental structures.  Congratulations to all the authors! Full text here: DOI: 10.1126/science.adn6354 #chemspace #openscience #research #science #drugdiscovery #chemicals #medicinalchemistry #drugdevelopment #chemistry #researchanddevelopment #search #chemicalindustry #science #structures

Exciting news in the world of biomolecular analysis! Refeyn is expanding its mass photometry product line, paving the way for more precise and efficient research. This advancement will empower scientists to unlock new insights in their studies. Let's embrace the future of analysis! Read more: https://lnkd.in/dSS7vHSM #BiomolecularBreakthrough #MassPhotometry #RefeynInnovation #FutureOfAnalysis #ScientificAdvancement #PrecisionResearch #UnlockingInsights #EfficiencyInScience #NextGenAnalysis #EmpoweringResearch

I'm thrilled to announce the publication of our collaborative research paper, titled "Exploring Fibrinogen's Affinity and Interaction with Trehalose for Protein Stabilization," in the esteemed Journal of Molecular Liquids (Q1, IF=6). This paper investigates the interaction between trehalose and fibrinogen, focusing on their structural characteristics and potential application in wound healing. Through a variety of analytical methods and computational modeling, it elucidates the formation of a stable complex between the two entities and highlights trehalose's role in enhancing protein stability and reducing cytotoxicity, suggesting its promise for wound dressing applications. I was responsible for conducting biophysical tests, including fluorescence, CD, and UV-thermal spectroscopic assays, as well as analyzing the resulting data and drafting these sections. I wholeheartedly thank all my collaborators on this paper and extend my congratulations to everyone involved. #TrehaloseInteraction #Fibrinogen #BiophysicalAnalysis #ProteinStability #StructuralCharacterization #WoundHealing #BiomedicalResearch #CytotoxicityTesting #ComputationalModeling https://lnkd.in/dzB4iPTn

Meet Volodymyr Kuzmenko, Principal Scientist at CELLINK, and a key player in our #HorizonEU PRISM-LT project! 🧬 Volodymyr and his team are pioneering new bio-inks with “helper” yeast and bacteria cells, designed to guide the differentiation of #StemCells. 🧫 This approach should help create complex tissue models with exciting applications in #CulturedMeat and #Healthcare. Explore more about our work at prism-livingtissues.eu and stay tuned for more updates! 🔍 #Bioprinting #SyntheticBiology #BioMaterials #HybridLivingMaterials #EICPathfinder #EUfunded #HorizonEurope

📢 ATP-Bio Year 4 Annual Report Is Here! We’re proud to share the Year 4 Public Annual Report, now available on our website. Discover how ATP-Bio is shaping the future of biopreservation through research, innovation, education, and ethical leadership. Key highlights include: 🌟 Advances in organ preservation, nanoparticle design, and thermodynamics. 🌟 A growing innovation ecosystem with start-ups and licensing successes. 🌟 Expanded outreach to underrepresented communities and future workforce development. 🌟 Pioneering ethical resources and policy discussions. 🖱️ Read the full report here: https://bit.ly/3DMyQJG #ATPBio #Biopreservation #Innovation #AnnualReport #NSFFunded #NSFERC

🔔 Welcome you to read one of our papers published "#Antifungal Activity of #Biosynthesized Silver #Nanoparticles (AgNPs) against #Aspergilli Causing #Aspergillosis: Ultrastructure Study" by Dr. Amr Hashem et al. 🔗 𝐋𝐢𝐧𝐤 𝐨𝐟 𝐭𝐡𝐞 𝐩𝐚𝐩𝐞𝐫: https://brnw.ch/21wLWwf 🎓 The study of natural systems has led to the development of #microbial and plant-extract-based methods that have replaced #nanosynthesis. #MDPI #openaccess #openscience #publishing #research #biomaterials

🚀 𝗘𝘅𝗰𝗶𝘁𝗶𝗻𝗴 𝗕𝗿𝗲𝗮𝗸𝘁𝗵𝗿𝗼𝘂𝗴𝗵 𝗶𝗻 𝗖𝗿𝘆𝗼-𝗘𝗠 𝗥𝗲𝘀𝗲𝗮𝗿𝗰𝗵! 🔬 It is thrilling to share out latest results using our cutting-edge NativeMP copolymer nanodiscs technology, Cubipol. We already used it to gather Cryo-EM data on the membrane Protein P2X4. This advancement is a key step ahead for all scientists who try to solve membrane protein stuctures. From construct to cryo-EM data in just a few weeks. This will speed up drug discovery studies aimed at membrane protein by alot! Cubipols are the newst addition to our NativeMP copolymer nanodisc technology and can be rightfully deemed as Next-Generation-Copolymer Nanodiscs. Are you interested in finding out more about this technology? Why don't we come together and talk a bit. https://lnkd.in/diEkvHcJ #CryoEM #Nanodiscs #science #MolecularScience #ScientificBreakthrough #ResearchInnovation #ScienceCommunity #drugdiscovery #research

CryoEM