Bioscience Association Manitoba’s Post

Come and hear what is new related to proposed changes to SRED, Capital Gains and how bioscience companies are meeting these and other challenges on their way to success.

Although the United States only accounts for 4% of the world’s population, it spends as much on drugs as the rest of the world combined. Despite this, health outcomes in the US are often worse than those in developing countries mainly due to the economic inefficiencies of the healthcare system. Pramod John spoke in September 2023 about how by focusing on outcomes and taking a common-sense approach, significant cost savings can be achieved. Watch here: https://lnkd.in/eU4idka7 If you enjoyed this talk, why not check out the Consilium Scientific Library? We have curated a selection of resources on topics including access to medicine, pricing and the pharmaceutical industry. 📖 Find books here: https://lnkd.in/dHTEHmHg 📽 Find films/podcasts here: https://lnkd.in/dY6fzWCB

New Policy Brief! 📑 IIPP PhD Researcher Giovanni Tagliani presents the case of bioproduction targeting in Thailand, charting the policy origins and how policy evolution has adapted along phases of innovation and technological sophistication. Read it here ➡️ https://lnkd.in/ez4TtxRy

The cytochrome P450 enzymes are of great importance and interest because they catalyze reactions that have profound effects on the biological activities of drugs, environmental chemistry, and endogenous compounds. As a consequence, the literature on these enzymes is too voluminous to read, scan, or even cite. And while the pace accelerates and the scope broadens to include more biochemical aspects such as amino acid sequencing and three-dimensional structural models of isoenzymes, the bench scientists struggle to perceive where the new information fits and what applicability it has, if any, to his/her work. Pharmacologists and toxicologists also feel swamped by the exponential increase in cytochrome P450 publications. The present paper is designed to assist by providing a framework for the prediction and interpretation of new data. It is an effort to summarize the functions of known human cytochrome P450s in terms of their specific catalytic activities, substrates, inducers, and inhibitors. Summaries are presented in tables for easy access to information. (Tables 5-21) The literature through 1996 is covered in the reference section. In some instances, references are to reviews that should be consulted for citations of the original literature. (Full text of the paper is available through Informa Healthcare Publisher only, or download the updated article: Summary of information on human CYP enzymes: human P450 metabolism data. Drug Metabolism Reviews 01/2002; 34(1-2):83-448.)

Italy's biotech sector is on the rise, with numerous innovative companies contributing to advancements in healthcare, agriculture, and environmental science. 🇮🇹🔬 While Italy shows impressive growth and potential, the United States remains the global leader in biotechnology, driving groundbreaking research and development. Explore the dynamic biotech landscape in Italy and see how these companies are making their mark alongside American industry leaders. 

🎯 Julija Lukaityte, head of our Life Sciences team, emphasizes the pivotal role of the Life Sciences sector in reshaping Lithuania's economic and scientific landscape. She highlights that the Life Sciences sector drives not only innovation in medical treatments but also sparks a broader bio revolution across industries, value chains, and the economy. Through genetic engineering, synthetic biology, and fermentation, the sector is advancing biomaterials, biofuels, food, and agricultural solutions🧪. Globally, these innovations are projected to generate economic impacts of $2-4 trillion. Aligned with our national ambition for Life Sciences to contribute 5% to Lithuania's GDP, our goal is to transform existing industries, foster innovation, and seize a share of this $4 trillion economic opportunity📈.

The present text contains the following updates: A discussion of ethanol metabolism by ADH and P450 enzymes is updated, & additional literature is cited (pp. 37–38). The text presents the updated data for the text/book Metabolism of Drugs and Selected Xenobiotics and publications Update Information on Drug Metabolism Systems-2009, Part I (PMID: 20307256) and Update Information on Drug Metabolism Systems-2009, Part II Summary of Information on the Effects of Diseases and Environmental Factors on Human Cytochrome P450 (CYP) Enzymes and Transporters ( PMID: 20302566). Newly added tables, e.g., Tables 3.4.1-2. and 3.4.1-3 and discussions (Chapter 10.3–3). Additional attention is put to the metabolism of PHYSIOLOGICAL COMPOUNDS (e.g., function, substrates, inhibitors, inducers) covering the 22 (of the total of 57) human P450s. The tables are related to the publication: Human cytochrome P450 enzymes 5-51 as targets of drugs and natural and environmental compounds: mechanisms, induction, and inhibition—toxic effects and benefits. Rendic SP, Peter Guengerich F. Drug Metab Rev. 2018 Aug;50(3):256-342. doi: 10.1080/03602532.2018.1483401. PMID: 30717606

Accelerate a scientific workflow has several interpretations- one that we all know very well was the way both the Pfizer and Moderna teams had to move the mRNA vaccine candidate through all processes and phases … I want to ask my esteemed network Bhaskar Mandavilli Arvind Srivastava, Ph.D. Leo Chan, Ph.D., MBA Candidate Lena Lee what does accelerating the workflow mean to you Love to hear your responses?

Reducing the environmental impact of research, especially on the Earth’s climate, is a major issue. Our colleague Samuele Lisi, PhD, a marketing and communication freelancer, will be hosting our upcoming webinar “𝗦𝘂𝘀𝘁𝗮𝗶𝗻𝗮𝗯𝗶𝗹𝗶𝘁𝘆 𝗶𝗻 𝘁𝗵𝗲 𝗹𝗶𝗳𝗲 𝘀𝗰𝗶𝗲𝗻𝗰𝗲 𝘀𝗲𝗰𝘁𝗼𝗿: 𝗵𝗼𝘄 𝗰𝗼𝘂𝗹𝗱 𝗶𝘁 𝘀𝗵𝗮𝗽𝗲 𝘆𝗼𝘂𝗿 𝗰𝗮𝗿𝗲𝗲𝗿?” Meet Joel Eichmann and 🔸Sandrine Foucher🔸, two industry leaders who can help you understand how you can integrate sustainability into your career. If you want to know more and ask your questions, you cannot miss this webinar! Register now following the link/QR code in the post below 👇

🚀 Elevate Your Brand at BIO Europe 🌍 Are you ready to showcase your innovation to the world? 📈 The BIO Europe conference is a great stage for life science leaders, and One Nucleus is preparing the ON Helix Review for release at the conference. This could be the spotlight your company needs to shine brighter at BIO Europe and beyond. Prices start at just £500 + VAT for One Nucleus members. Why Sponsor the ON Helix Review? ✨ Unparalleled Visibility: Reach thousands of top-tier professionals and decision-makers in the international life sciences. ✨ Targeted Audience: Connect directly with your ideal customers, investors, and partners. ✨ Premium Placement: Stand out in a comprehensive review that attendees trust and reference. 📅 Don’t miss this golden opportunity to amplify your brand’s impact at one of the most influential events of the year. Secure your ad space now and be part of the conversation driving the future of life sciences. 🌟 Join us in transforming the future of life sciences and biotechnology. Your innovation deserves the spotlight! 🔗 Find out more here https://lnkd.in/eJ-TwrdB #BIOEurope #LifeSciences #Biotech #Innovation #Healthcare #BusinessGrowth #Marketing #Conference2024