BioSymetrics’ Post

Looking to use co-culture models in your research? We've done the "heavy lifting" with a range of in vitro co-culture user guides! Stepping up from mono-culture to co-culture experiments can be technically challenging, which is why we're offering our expertise to groups looking to benefit from more complex in vitro models. Take a look at our easy-to-follow protocols to unlock the benefits of co-culture iPSC models, including: • Cortical excitatory neurons and astrocytes • Cortical excitatory neurons and cortical inhibitory interneurons • Tri-culture of cortical excitatory neurons, cortical inhibitory interneurons and astrocytes Guided by our expertise, you can incorporate greater complexity into your neurodegenerative disease models and drive more human-relevant data outcomes. Take a look at these user guides here: https://hubs.la/Q02rP1hd0 If you'd like to access our decade of experience for your co-culture research, get in touch with us at operations@axolbio.com to see how we can best help you. #iPSCs #AlzheimersDisease #DrugDiscovery #CoCulture #TriCulture

Looking to use co-culture models in your research? We've done the "heavy lifting" with a range of in vitro co-culture user guides! Stepping up from mono-culture to co-culture experiments can be technically challenging, which is why we're offering our expertise to groups looking to benefit from more complex in vitro models. Take a look at our easy-to-follow protocols to unlock the benefits of co-culture iPSC models, including: • Cortical excitatory neurons and astrocytes • Cortical excitatory neurons and cortical inhibitory interneurons • Tri-culture of cortical excitatory neurons, cortical inhibitory interneurons and astrocytes Guided by our expertise, you can incorporate greater complexity into your neurodegenerative disease models and drive more human-relevant data outcomes. Take a look at these user guides here: https://hubs.la/Q02rN_Nd0 If you'd like to access our decade of experience for your co-culture research, get in touch with us at operations@axolbio.com to see how we can best help you. #iPSCs #AlzheimersDisease #DrugDiscovery #CoCulture #TriCulture

At Axol we are supporting the iPSC community by sharing our expertise to enable better human disease models in order to help drive your science and ultimately patient outcomes. Stepping up from mono-culture to co-culture experiments can be technically challenging, which is why we're offering our expertise to groups looking to benefit from more complex in vitro models. Take a look at our easy-to-follow protocols to unlock the benefits of co-culture iPSC models, including: • Cortical excitatory neurons and astrocytes • Cortical excitatory neurons and cortical inhibitory interneurons • Tri-culture of cortical excitatory neurons, cortical inhibitory interneurons and astrocytes Guided by our expertise, you can incorporate greater complexity into your neurodegenerative disease models and drive more human-relevant data outcomes. Take a look at these user guides here: https://hubs.la/Q02rP1hd0 If you'd like to access our decade of experience for your co-culture research, get in touch with us at operations@axolbio.com to see how we can best help you. #cellculture #stemcells

AI-based approaches to drug discovery won't be useful if they are expediting a flawed process. Our approach is, and always has been, to leverage AI/ML to better understand and model disease biology, and then address in vivo phenotypes using novel chemistry. We saw evidence of this working with our epilepsy program, and now are looking to expand to other areas of neurological disease. If you're at #bio2024 feel free to reach out, always happy to chat. Looking forward to a great meeting! #ai #drugdiscovery

Don't miss it! This Friday from 1-2 p.m. CT, we'll be hosting the Professional Development Café, CRISPR-mediated Regulation of Human Myogenesis + Disease. https://lnkd.in/gj8-cfRN Join April Pyle, PhD and Graca Almeida-Porada, MD, PhD for a discussion about the utilization of #CRISPR #Cas9 in conjunction with older technologies in order to reimagine #genetherapy and #celltherapy treatments, particularly for #Duchenne muscular dystrophy (#DMD). Interested in learning about even more advances in muscular dystrophy? Check the comments for details about our hybrid event, "Breakthroughs in Muscular Dystrophy."

Session on Targeting the Brain at #Bio2024 The difficulties in translation research in Neurodegeneration can be overcome with recent use of patient iPSC derived neurons and organoids to validate your compound and endpoint/phenotype in the relevant disease background. Are you interested in testing your compound in patient derived iNeurons? let's chat!

BCBN Feed: Vizgen and Ultivue Merge to Enable Deeper Insights into Disease Mechanisms and Drive Innovation in Spatial Multi-Omics https://lnkd.in/gPp2-h-z CAMBRIDGE, Mass.--(BUSINESS WIRE)-- #neuroscience--Vizgen and Ultivue Merge to Enable Deeper Insights into Disease Mechanisms and Drive Innovation in Spatial Multi-Omics ... [...]

The expert insights in this video ring true. My key takeaways:   “You have to be agile … Genetic medicine is changing rapidly. We need to properly and appropriately give information to patients and families, but also to the next generation of providers currently implementing genomic science.” Maria Blazo, MD   “A key issue to making genomics actionable is to disseminate it .. bringing genetics more into primary care facilities where diagnoses can be recognized, orders can be placed for broad-based sequencing, and information can be appropriately interpreted for treatment.” Mark J. Kiel MD PhD   Listening to feedback from healthcare leaders helps inform our strategies and advance our mission of going beyond the science of genetics to deliver life-changing answers to the providers and patients who need them most. Thank you, Dr. Blazo and Dr. Kiel!   #genetics #heathcare

A brief update from our partners at @TheJacksonLaboratory Rare Disease Translational Center! They have completed the verification stage and our CASK microinjection has received the “all clear” to begin! JAX is aiming for the process to begin mid-June, with pups roughly 3 weeks after that. This is an exciting update! We will keep you informed of new developments. Just a reminder that mouse models take an average of 15 months if all goes well. So, we still have a ways to go but progress is happening! Watch this space, more to come. #jaxrdtc #jaxlab #mousemodel #caskgene #caskresearch #kickcask #projectcask