Biosynth’s Post

AD | The human insulin is structurally identical to the insulin produced by the pancreas in the human body. This structural identity is obtained by recombinant- DNA technology utilizing Saccharomyces Cerevisiae (bakers’ yeast) or E. Coli as production organism. Other methods for cells disruption can be used but the advantages of the High pressure homogenization are many: It is a mechanical process quick and effective; It is a continuous process; the results obtained in laboratory are perfectly reproducible in industrial scale; you can vary pressure in order to find the right degree of cells rupture; no need to add expensive substances like chemicals or enzymes; no contamination of the product by toxic substances; the degree of denatured proteins at the end of the process is small. Find out more at Laboratory Homogenizers (gea.com) https://lnkd.in/ev2Mk3aV #GEA #homogenizers #humaninsulin #celldisruption

NEWS ALERT: Efficient removal of pharmaceutical contaminants from water and wastewater using immobilized laccase on activated carbon derived from pomegranate peels. "In this study, pomegranate peels (PPs) as an abundant fruit processing waste was used to produce cost-effective, eco-friendly, and high-quality activated carbon. The produced carbon (fossil free activated carbon) was used for immobilizing laccase to remove a range of emerging pollutants namely diclofenac, amoxicillin, carbamazepine, and ciprofloxacin from water and wastewater. The loaded activated carbon by laccase (LMPPs) and the unloaded one (MPPs) were characterized using advanced surface chemistry analysis techniques. MPPs was found to have a porous structure with a large surface area and an abundance of acidic functional groups..." Read more here: https://lnkd.in/gmxakCff #wastewater #watercontaminants #environmentalscience #environmentalmanagement

I am pleased to present my latest research highlighting a sustainable technology for Palladium-catalyzed Buchwald–Hartwig aminations of aryl fluorosulfates, an alternative, non-PFAS pseudohalide, under aqueous micellar conditions. The research showcases the development of a new Palladium Oxidative Addition complex (OAC) developed specifically to match the needs of the fine chemicals industry, not only in terms of functional group tolerance but also reflecting time considerations associated with these important C–N couplings. The new complex based on the BippyPhos ligand is used at low loadings and under aqueous micellar conditions. Further applications like Late-stage functionalization and Pharmaceutical diversification have also been demonstrated. I would like to thank my team: Robert Lammert Jr., Kylee Rodriguez, Jordan Yirak, John Saunders, and Dr. Rahul Kavthe for their timely contributions. Check out the article in Angewandte Chemie https://lnkd.in/dnKEgQ-d

Biosurfactants, which are environmentally friendly and versatile microbial molecules with unique amphiphilic properties, have numerous applications across various industries, particularly in the petroleum sector, where they offer sustainable alternatives to synthetic surfactants for processes such as hydrocarbon recovery, product formulation, and innovative uses, making them a promising focus for future research and development in the oil industry. Link: https://lnkd.in/gaZ2Zxf Link: https://lnkd.in/dayUe8HZ Keywords: #Biosurfactants #Biodegradability #Hydrocarbon #Sustainable

🌱Excited to share our latest publication in Sustainable Chemistry and Pharmacy (Elsevier): "Sustainable synthesis of 2-ethyl hexyl oleate via lipase-catalyzed esterification: A holistic simulation and cost analysis study". ✅ Our study highlights the economic and environmental benefits of lipase-catalyzed synthesis, achieving a 91% conversion rate under optimized conditions. A detailed cost analysis shows production at $2109 per ton with a 28% profit margin, supported by a projected NPV of $14.7M, ROI of 583.91%, payback period of 6 years, and IRR of 23%. These findings underscore the potential of this cleaner and profitable approach in fatty acid ester synthesis. Read more using the personalized URL that provides 50 days of free access to the article: https://lnkd.in/eUaXuW5c #Sustainability #GreenChemistry #Biocatalysis #EconomicAnalysis #Research #Innovation

♻️ Chromatography adds more than 80% of solvent waste to your processes. Time to change that... 👉🏽Solvent use and waste generation is a critical factor to improve sustainability in your peptide processes and to save cost. Reversed-phase chromatography consumes significant amount of HPLC-grade acetonitrile which is toxic, generates massive amounts of waste and is expensive to purchase. 👉🏽Enter a new paradigm of peptide purification with catch-and-release purification and cut down acetonitrile use by more than 90% and organic waste generation by over 80%. 💡Learn more about the future of sustainable peptide purification in our latest application note: https://lnkd.in/dT5cA2tN #greenchemistry #peptides #purification #purepep

🚀 Case Study Spotlight: Advancing Sustainable Nicotine Production 🌿 At Enzymicals, we're thrilled to share a breakthrough in sustainable chemistry! Back in 2017, we embarked on an exciting journey with Zanoprima Lifesciences Ltd, UK, to develop an innovative imine reductase (IRED) catalyzed process for producing (S)-Nicotine. Our team: ✅ Developed a highly efficient biocatalyst ✅ Optimized the biocatalytic process for chiral intermediate production ✅ Supported scale-up to commercial production The result? Synthetic nicotine is now on the market, offering significant environmental benefits. Compared to tobacco-derived nicotine, synthetic nicotine: 🌍 Emits up to 12 times fewer greenhouse gases 💧 Uses significantly less water More info on the Carbon and Water Footprints of Tobacco-Based vs. Synthetic Nicotine: https://lnkd.in/deCVYRQF Interested in how Enzymicals can support your innovative projects? Reach out to us to learn more about this case study and explore how our expertise can bring your ideas to life. Come and visit us at our stand J50 at the Chemspec Europe - Int. Exhibition for Fine & Speciality Chemicals. We look forward to seeing you! #SustainableChemistry #Biocatalysis #Innovation #GreenTech #CaseStudy #SyntheticNicotine #EnvironmentalImpact #Biotechnology #GreenCheistry

This study discusses the use of metal/metal oxide nanocomposites as antibacterial agents which could potentially be applied in water treatment to remove bacterial contaminants. #Nanocomposites #AntibacterialAgents #WaterTreatment #Innovation

🌊💊 Addressing Challenges in Treating Pharmaceutical Wastewater 💊🌊 🔬 Complex Composition: Pharmaceutical wastewater presents a complex mix of constituents, including active pharmaceutical ingredients (APIs), solvents, heavy metals, and organic impurities, necessitating tailored treatment approaches. 💡 Innovative Solutions: Employing advanced oxidation processes (AOPs) like ozonation and UV/H2O2, alongside activated carbon adsorption, enables effective removal of APIs and recalcitrant organic compounds from wastewater streams. 🌿 Environmental Impact: Prioritizing sustainability, treatment systems incorporate energy-efficient technologies, minimizing sludge and chemical residuals. Embracing closed-loop water management reduces water usage and waste generation. 📊 Performance Monitoring: Real-time monitoring and control systems optimize process parameters, ensuring consistent treatment performance even amidst fluctuating influent compositions and operating conditions. 🌍 Global Health Impact: Robust wastewater treatment mitigates pharmaceutical contamination risks, safeguarding public health and ecosystems. Exo-Green Technologies is at the forefront of advancing these solutions, aligning with the imperative of protecting natural resources for future generations. Join the journey towards pioneering pharmaceutical wastewater treatment for a cleaner, healthier planet with Exo-Green Technologies! 💧✨ #PharmaceuticalWastewater #Sustainability #Innovation #ExoGreenTechnologies #ExoGreen

A Solvent of Choice: The Significance of the Dimethyl Formamide (DMF) Market 📈💧 #DimethylFormamide (#DMF), known for its effectiveness as a #solvent, is an integral part of various manufacturing processes. It's not just a #chemical; it's a facilitator of innovation and efficiency in industries ranging from pharmaceuticals to electronics. In the world of complex #ChemicalProcesses, DMF plays a pivotal role. 🚀⚗️ 📈 The market for DMF is growing, driven by its versatile applications in producing synthetic leathers, fibers, coatings, and adhesives. Its ability to dissolve a wide range of substances makes it indispensable in the formulation of high-quality products. 💡 Beyond its primary role as a solvent, DMF's unique properties are essential in the production of pharmaceuticals and crop protection #chemicals, showcasing its versatility and importance in supporting health and agriculture. 💊🌱 🌿 As industries strive for sustainability and safety, the DMF market is adapting to advancements in production methods and recycling techniques. It's about meeting industrial needs while being mindful of environmental and health standards. 🍃♻️ ✨ Gain insights into the #DimethylFormamideMarket in our article at https://bit.ly/3vG5Hf2 #ChemicalIndustry #IndustrialSolvent