BPS Bioscience Inc.’s Post

🔬 One important aspect of fully comprehending tumors is understanding their metabolism. #Cancer cells undergo metabolic modifications to meet high bioenergetic and anabolic demand during tumorigenesis. 🔎 Monitoring metabolite dynamics and lactate production in physiologically relevant patient-derived models can provide valuable data for understanding metabolic perturbations during disease progression, #drug response and resistance. ✨ We demonstrate an automated workflow using the #pumasystem to assess metabolic changes in triple negative breast cancer (TNBC) #tumoroids in response to treatment with anti-cancer drugs. 💡 Learn more: https://lnkd.in/gu7mCNPS 

Revolutionary Discovery: Local Anesthetic Drug Effective in Killing Cancer Cells! Lidocaine functions as a local anesthetic by blocking signals at nerve endings in the skin, making it a go-to choice for pain relief during medical procedures. However, its newfound role in cancer treatment has left many baffled. At the heart of this discovery lies the activation of a taste receptor known as T2R14 by lidocaine. This receptor, responsible for detecting bitterness, was found to be present in high concentrations within various cancer cells, especially those residing in the oral cavity and throat. The tantalizing possibility that lidocaine interacts with cancer cells through this receptor led researchers at the University of Pennsylvania to explore this hypothesis. #cancer #oncology #drugdiscovery #drugdelivery #medicalsciences #pharmaceutics #medicine #research #health #immunotherapy

Comparative Cytotoxicity Evaluation of Heat-Assisted vs Cold Water Extractions of Six Medicinal Fungi 🍄 against Breast and Lung Cancer Cells 🔬 https://lnkd.in/dN-N-DBJ #SDG3 #SDG9 #SDG12 #cytotoxicity #AqueousExtraction #medicinalfungi #openaccessjournal #ftbjournal

Commonly Used Anesthetic is Surprisingly Effective at Killing Cancer Cells: Lidocaine functions as a local anesthetic by blocking signals at nerve endings in the skin, making it a go-to choice for pain relief during medical procedures. However, its newfound role in cancer treatment has left many baffled. At the heart of this discovery lies the activation of a taste receptor known as T2R14 by lidocaine. This receptor, responsible for detecting bitterness, was found to be present in high concentrations within various cancer cells, especially those residing in the oral cavity and throat. #cancer #oncology #prostatecancer #skincanc #innovation #biotech #celltherapy #genetherapy #immunotherapy #drugdiscovery #drugdelivery #medicalsciences #pharmaceutics #medicine #research #health

Integrated RNA-sequencing and network analysis approach to identify the Hub genes and vital pathways associated with gastric cancer. https://ow.ly/6kYa50Qx2G6 #GastricCancer #MolecularBiology #Pharmacology

AKT, also known as Protein Kinase B (PKB), is a crucial target in cancer therapy. The AKT Pathway (or PI3K-Akt Pathway) promotes cell survival and growth in response to extracellular signals. SignalChem Biotech, now part of Sino Biological, Inc., offers an extensive range of AKT kinases for oncology research. Discover how our kinase enzyme products can help advance your research! Explore More: https://ow.ly/8b9Q50SNGfn #AKTPathway #CellSignaling #ProteinKinases

🌱✨ Publication Alert! Our comprehensive review on "Exploring Mechanisms of Tumorigenesis and Plant-Based Therapies" is now live! 📚🔬 Dive into the fascinating world of cancer pathogenesis and treatment strategies, where plant-based compounds take center stage. 🌿💪 From modulating enzymes to targeting key signaling pathways, these compounds, including flavonoids, polyphenols, and glucosinolates, show immense potential in cancer prevention and treatment. The study explores mechanisms driving tumorigenesis and the promising role of plant-derived therapies in cancer chemotherapy. 🌐👩🔬 Explore the full article for an in-depth look into the mechanisms driving tumorigenesis and the promising role of plant-derived therapies in cancer chemotherapy. 🚀 #CancerResearch #PlantBasedTherapies #ScientificDiscovery #ResearchUpdate 🌺🎉 https://lnkd.in/e9jbDVCB

Integrated RNA-sequencing and network analysis approach to identify the Hub genes and vital pathways associated with gastric cancer. https://ow.ly/mMJZ50Qx2G7 #GastricCancer #MolecularBiology #Pharmacology

Calm Water Therapeutics' (CWT) PEGPlus technology shows great promise in mitigating ADC induced keratopathy, a serious complication for many receiving ADC based treatments for cancer. In the article, PLL-g-PEG Polymer Inhibits Antibody-Drug Conjugate Uptake into Human Corneal Epithelial Cells In Vitro, the researchers demonstrate virtually complete ADC uptake inhibition with clinically relevant concentrations of PEGPlus. And, in May, CWT released the results from a 30 day dry eye disease study that demonstrated PEGPlus' superior impact on dry eye signs and symptoms. CWT is actively developing products to treat both dry eye and ADC keratopathy. https://lnkd.in/ewGDPAne #ADC #DRYEYEDISEASE #ONCOLOGY