Cambridge Gravity’s Post

I had the pleasure to be interviewed by Jessica from the The Antibody Society to describe the science and research behind the microscopy image I submitted for the microscopy competition and got its place as November image in the 2024 calendar! Science is also art and microscopy allows us to visualize the beautiful world of biology. For those working with antibodies or anybody-based therapies like me and my research group, microscopy is fundamental to assess the performance of our mAb candidates as drug delivery vehicles. If you wanna hear more about it, here is the link! #research #antibody #microscopy #science #adc #drugdevelopment The Antibody Society

Great research John. Evidence suggests that similar impacts have been in other disorders such as diabetes. The COVID-19 pandemic has had profound impacts on healthcare delivery, and one of the critical areas affected has been the timely diagnosis and management of diabetes. During the pandemic, many individuals faced delays in accessing routine medical care, leading to late diagnoses and complications in diabetes management. For people living with diabetes, these delays have resulted in significant health risks. With routine appointments postponed or canceled, many missed essential screenings and monitoring. This lack of regular medical oversight has led to worsened glycemic control, increased hospitalizations, and severe complications such as cardiovascular issues, neuropathy, and retinopathy. The disruption in healthcare services also meant that many individuals could not receive timely education and support for diabetes management. This situation exacerbated stress and anxiety, further complicating the condition. As we navigate the post-pandemic landscape, it's crucial to prioritize catching up on missed care, ensuring timely interventions, and supporting patients in managing their diabetes effectively. The pandemic has underscored the importance of resilient healthcare systems and the need for innovative solutions to ensure continuity of care even during global crises. By learning from these experiences, we can better prepare and adapt to future challenges, ensuring that individuals with diabetes receive the care and support they need without interruption. #DiabetesCare #COVID19Impact #HealthcareInnovation #ChronicDiseaseManagement #PatientSupport #HealthcareResilience

“I was always interested in engineering cells for better function.” 2020 BYI John Blazeck, PhD, Assistant Professor at the Georgia Institute of Technology shares about the research journey working on synthetic antibody repertoires for vaccine development, therapeutic isolation, and the study of adaptive immunity. Watch the video: https://ow.ly/vPfl50ThT8S #immunoengineering #immunology #engineering #metabolism #humanhealth #proteinengineering #cellularengineering #byi #phd #academia #lab #research #scientist #vaccinedesign #syntheticbiology #personalizedmedicine #enzymeengineering #customantibodies #like #follow #comment #researcherlife #scientistlife

Novel exciting study by Betty Kim, Weng Jiang and collaborators!

https://lnkd.in/dPZez-qB via @researchgate https://lnkd.in/dPZez-qB Happy to share that my scientific outcome is reaching different research groups and getting more known. My first published abstract at ESMO - European Society for Medical Oncology- Paris 2024 highlighted the impact of H2S and its synthesizing enzymes on metabolic reprogramming in breast cancer

Michael Levin's citation: "Cancer is a Dissociative Identity Disorder of the morophogenetic intelliegence." Source https://lnkd.in/e8g3dRs7 His paper Levin, M. (2021). Bioelectrical approaches to cancer as a problem of the scaling of the cellular self. Progress in biophysics and molecular biology, 165, 102-113. https://lnkd.in/eDxGcwSc ___ What I think Michael means in this citation above is that in cancer the cell become encapsulated, it closes the gap junctions, which leads to loss of communications with the neighbor cells, which, in turn, leads to the fragmentation of "identity" - the cell that had been a part of the collective identity of the entire cell collective regressed into being a single-cell organism. (There is no cell collective when communications are impaired) Once this cell became isolated from neighbors, it starts treating the rest of the cells as the external environment ( e.g. food) and it reproduces itself, leading to metastasis. This is not just an opinion, Levin's lab conducted experiments where they triggered a metastatic melanoma in a frog JUST by closing the cell's gap junctions. - no genetic changes, no carcinogens - just by isolating one cell from the neighbors, that's it. Most importantly, in their experiments they were able to prevent and normalize the tumors made from human oncogenes in a frog by... forcibly reconnecting the cells back to their neighbors. Of course, each kind of cancer is diverse, super complex and we have more questions than answers, but I think Levin's work is super impressive and hopefully can lead to treatments.  __ What do you think?

Check out our latest video featuring BC Cancer's Reka Pataky discussing economic evaluations using Value of Heterogeneity. She used a post-implementation evaluation of third-line therapy in metastatic colorectal cancer to highlight approaches to handling heterogeneity. Watch the video: https://lnkd.in/gEWBnKBr #CancerResearch #ColorectalCancer #HealthResearch #HealthEconomics #Genomics #GenomicTesting

🔬 New Episode Alert! 🔬 We are thrilled to present our latest video featuring Vikash Chandra, who delves into candidate genes for drug targeting in Type 1 Diabetes. This episode offers groundbreaking insights and explores innovative research paths that could lead to new treatments. 🌟 Watch the full episode here: https://lnkd.in/grSFaqTw Join the conversation and stay updated on the latest in diabetes research by following us at The Sugar Science. #DiabetesResearch #Type1Diabetes #DrugDiscovery #ScientificResearch #TheSugarScience #NonProfit

👉 You're invited to attend the inaugural lecture of Prof. Dr. Misha Luyer tomorrow, April 5th, 2024 from 4:00-5:00 pm at the Blauwe zaal in the TU/e Auditorium. The lecture topic is 'Technology to Improve Oncological Surgery and Perioperative Care.' If you cannot join in person, you can also participate online through this link: https://lnkd.in/eMZhWMQw. Luyer is currently working on a promising technique that can be used for detecting and characterizing pancreatic cancer, and that is artificial intelligence. The implementation of new techniques such as artificial intelligence requires the collaboration of various parties, including healthcare institutions, academic institutions, and industry. Such research is taking place within the eMTIC community.   Read more in this article (Dutch only): https://lnkd.in/gq6Gz8GT #emtic #collaboration #pancreaticcancer #oncology #perioperativecare

Second Ph.D. paper from Luke Trinity's thesis is out now -- "Tying the knot: Unraveling the intricacies of the coronavirus frameshift pseudoknot". In this study, we employed the KnotAli and Shapify algorithms to enhance our knowledge of RNA structures in coronaviruses, including SARS-CoV-2. By examining the frameshift elements in 181 coronavirus RNA sequences, we identified crucial structural transitions that could improve the targeting of antiviral therapies. This research not only deepens our understanding of RNA structure-function relationships but also propels the development of innovative treatments for those impacted by these viruses. #Virology #RNAresearch #Coronavirus #covid19 RNA Canada ARN (formerly called Canadian Consortium of RNA Researchers) University of Alberta