Canadian Institutes of Health Research | Instituts de recherche en santé du Canada’s Post

Understanding the history of clinical research helps us to learn lessons and ensure we do better in the future.     This week, Dr Heidi Green looks back at the history of clinical research.  We’ve come a long way from the four bodily humors (blood, phlegm, yellow bile, and black bile) to oranges and lemons, and the first randomised controlled trial.     What will we do better in the future?    Read the full post here: https://lnkd.in/eN5gn6CZ   #ClinicalResearchHistory #EvolutionOfClinicalResearch #HealthResearchEquity #TheCOUCHWay   

Great pub by Hughes & Albert Garcia-Romeu, PhD tackling an important issue historically endemic to psychedelic research. We found the same outcomes when conducting the Global Psychedelic Survey 2023 (GPS 2023; https://lnkd.in/gs4_X9CN), which is why for GPS 2025 were honored to work with academics around the globe to make it available in Spanish, Portuguese, Italian, Farsi, Hebrew, Polish, German and French…with more languages to come!. We hope this will increase the diversity of respondents, and fill important gaps of knowledge re. psychedelic access and use in non-anglophone populations all over the world. #psychedelicscience #equitableaccess #colorfulworld #gps2025

This review provides crucial insights into the ongoing issue of underrepresentation in clinical trials for psychedelic-assisted treatments. By highlighting the dominance of non-Hispanic White participants and the significant underrepresentation of Black, Asian, Latinx, and Indigenous populations, the authors draw attention to a pressing need in the field. Addressing this disparity is not only a matter of ensuring the #safety and #efficacy of treatments for all populations but also a step towards promoting #health #equity. Future #research must prioritize #diversity in study participants to develop more universally applicable and effective psychedelic-assisted therapies. #psychedelic #research #clinicaltrials

How familiar are you with the history of #clinicalresearch? Read this article to find out.

NEW Business Trip Podcast: “Chemical Conversations: Comparing Psychedelic Compounds in Therapy” We get into some of the big unanswered questions in the psychedelic industry today. Full episode here: https://lnkd.in/gb2w4csh

Today, I celebrate yet another significant achievement as we unraveled the potential of interleukin-26 as both a biomarker and a target for therapeutic intervention in severe asthma. Much gratitude to the dedicated team at KI whose relentless efforts brought this breakthrough to fruition. The essence of scientific exploration transcends mere discovery; it embodies the profound dedication of passionate researchers in piecing together intricate puzzles at the microcosmic level, even amidst apparent impossibilities. These incremental advancements, forged through dedication and perseverance, have paved the way for some of the most transformative breakthroughs, that have addressed some of humanity's most pressing health challenges today. Happy reading -:) chrome-extension://efaidnbmnnnibpcajpcglclefindmkaj/https://lnkd.in/dnsmpaZt

In the words of Farideh - 'we've never really studied the female body' Despite advancements in health science, chronic period pain remains largely normalised and under-researched, leaving many women to suffer needlessly. As someone who lived with Primary Dysmenorrhoea for 19 years before being diagnosed with #endometriosis (where it then became Secondary Dysmenorrhoea), I understand how vital and urgent the quest for better treatment outcomes is. This week on Phoenix Sound, we're proud to feature Prof Kylie O'Brien, Chief Scientific Officer at Cannim Group, sponsors of The Lumir Mission Plant-based Medicine for Primary Dysmenorrhoea (Period Pain) Study. Conducted by NICM Health Research Institute’s Associate A/Prof Mike Armour, the study aims to assess the potential effectiveness of plant-based medicine in alleviating period pain over a 6-month duration. Join us on substack as we walk through the science behind this study, including information on how to participate in this groundbreaking research. #phoenixsound #womenshealth #medicinalcannabis #substack

Looking forward to kicking off the year's "Research Spotlight" series next week! Join Prof. Roger Barker and me to hear about serotonin in PD. #parkinsons #serotonin #drugdevelopment Neurolixis

Want to learn the fundamentals of identifying pneumonia in kids? This video teaches how to identify and treat pneumonia in infants and children. Chapters in this video cover the pathophysiology, clinical presentation, diagnosis, management, and complication that arise in the treatment of pneumonia. https://lnkd.in/e-unCKTW

...a nice achievement (50 cites and counting...) for our paper on how single nucleotide polymorphisms (SNPs) in brain-derived neurotrophic factor (BDNF) can drive obesity. Thanks to everyone for reading our work! #aging #obesity #bdnf #SNP #receptor