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🪩 Reactive oxygen species (ROS) and habitual inflammation make diabetic wounds tough to treat. 🪩 In this article, Yizhou Dong and team describe a mRNA-LNP topical treatment that is used to aid diabetic wound healing (in mice). 🪩 "Scientists engineered a formulation of diverse ROS-responsive trisulfide-derived #lipid #nanoparticles, which significantly reduce ROS at wound sites. And they've figured out a way to make the lead trisulfide-derived lipid nanoparticle deliver interleukin- (IL-)4 #mRNA to the area to temper the wound inflammation microenvironment." Original Publication: https://lnkd.in/eFwMu-PJ How We Learned About the Publication: https://lnkd.in/e8UGN5Er #LNP #Diabetes #WoundCare #Research #MountSinai Mount Sinai Health System #topical #topicals #transdermal #drugdelivery #DDS #Innovation

Lipid Nanoparticle-mRNA Topical Aids Diabetic Wound Healing in Mice

Lipid Nanoparticle-mRNA Topical Aids Diabetic Wound Healing in Mice

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