AJMC: Center on Health Equity & Access’ Post

A well-written article today titled "Navigating the Present and Shaping the Future of Sickle Cell Disease." #GeneTherapy #CellandGeneTherapy #Casgevy #Lyfgenia #PatientAccess #SupplyChain #Logistics #Apheresis

Today is World Sickle Cell Awareness Day! In this AJMC - The American Journal of Managed Care article, we shine a spotlight on a critical issue affecting millions worldwide—sickle cell disease (SCD). The challenges faced by those living with SCD are profound, but so are the advances being made in treatment and care. We invite you to join us and dive into the current landscape and the promising future of sickle cell disease. Explore new therapies and the ongoing challenges in logistics, access, and cost. Read more! #SickleCellAwareness #GeneTherapy #HealthCareInnovation #AJMC #WorldSickleCellDay #PatientAdvocacy #SCD

The potential impact of a recent development for individuals with sickle cell anemia is worth noting. An advisory committee has conducted a review of a treatment utilizing the CRISPR-Cas9 gene-editing system, with the aim of modifying the type of red blood cells produced by the body. This approach holds promise for reducing complications like infections and strokes associated with sickle cell disease. It's significant that the committee members have expressed the view that the benefits of this treatment appear to outweigh the associated risks. We eagerly await the regulatory decisions and further advancements that will pave the way for making this treatment accessible to those affected by the condition. #sicklecellanemia #sicklecellawareness #healthnews https://lnkd.in/gaSz6eKk

We are thrilled to introduce a new series showcasing the powerful features and benefits of the Clinical Knowledgebase (CKB), a cutting-edge resource we acquired from The Jackson Laboratory this spring. CKB is a vital tool for researchers and clinicians, offering unparalleled insights into somatic genomics, crucial for advancing cancer diagnosis and treatment. We’re launching our series, with an overview of the comprehensive somatic data offered by CKB. Central to CKB’s value is its vast and valuable somatic dataset, setting it apart and making it the industry standard. CKB is an extensively curated database encompassing gene and variant annotations, therapeutic insights, and both diagnostic and prognostic information specifically related to oncology. It offers comprehensive details on the impact of somatic gene variants on protein functions and links these variants to targeted therapies with robust efficacy evidence. Additionally, CKB includes precise criteria for clinical trial eligibility based on specific genomic alterations. With data on over 2000 genes and nearly 47000 somatic variants, CKB empowers researchers and clinicians with critical insights into essential genes like BRCA1, BRCA2, EGFR, KRAS, BRAF, RET, and MET. These insights can drive breakthroughs in cancer research and personalized therapies. By providing comprehensive and up-to-date genetic information, CKB enables more accurate diagnostics and targeted treatment options. Researchers can now leverage this wealth of data to uncover new therapeutic pathways and improve patient outcomes. Stay tuned for more posts in this series as we continue to uncover the capabilities and value of CKB. For more details, visit: https://lnkd.in/g-w2MNV3 #ClinicalKnowledgebase #CKB #GeneticResearch #PrecisionMedicine

New treatment options are offering hope for individuals living with sickle cell disease. While there is still much work to be done, raising awareness and supporting efforts to improve the lives of those affected by this challenging condition is crucial as research continues to evolve. #SickleCellAwareness #HealthcareImprovements

SenCID enables the reconstruction of senescent trajectories under normal aging, chronic diseases, and COVID-19. Additionally, when applied to single-cell Perturb-seq data, SenCID helps reveal a hierarchy of senescence modulators. Overall, SenCID is an essential tool for precise single-cell analysis of cellular senescence, enabling targeted interventions against senescent cells.

Did you know it is World Parkinson’s Day? We'd like to share some of our key articles which highlight how far we've come in #Parkinson's research! Identifying Parkinson’s Inhibitors | https://bit.ly/3vNrtOm Parkinson’s Disease Diagnosis Goes Skin Deep | https://bit.ly/33iNHGL Parkinson’s Progress | https://bit.ly/3PSYhM4 #WorldParkinsonsDay #Parkinsonsday

Good information about neurodegenerative diseases.

Discover how Bayesian network models are revolutionizing disease prediction and treatment decisions in hematological malignancies. Read More: https://shorturl.at/6kz4F #statswork #BayesianNetworks #DiseasePrediction #PersonalizedMedicine.

Xtalks recently talked to us about Treg therapy for diseases like #ALS, #FTD and others. Listen to the full discussion here to learn more about our lead candidates and their potential to treat #neurodegenerative diseases. https://lnkd.in/e_5c3fRe #ENDFTD #Coyatherapeutics $Coya