Cerevance’s Post

A recent Perspective Paper published by Prof. Heresco-Levy and Prof. Lerer in the journal of Molecular Psychiatry presents novel suggestions and clinical implications supported by compelling evidence, focusing on the synergistic treatment of neuropsychiatric disorders using serotonergic psychedelic (SP) and NMDAR modulator combination therapies. Preclinical studies performed in the Lerer laboratory have already shown that these combination treatments attenuate the head twitch response and therefore suggest reduction of psychotic-like effects in mice, warranting further investigation in human studies. Accumulating animal models and clinical data to date indicate that these therapies may suitably address major unmet medical needs such as treatment-resistant schizophrenia and depression. Negev Labs is proud to support the pioneering work of Prof. Bernard Lerer and his dedicated team at Hadassah Brainlabs Center for Psychedelic Research, which is a new initiative dedicated to developing novel neuroplastogens for the treatment of severe mental health disorders. #neuroplastogens #neuroscience #psychiatry https://lnkd.in/eMxVewuJ

Precision medicine is revolutionizing the healthcare industry, and mental health is no exception. Our client and Chief Medical Officer of HMNC Brain Health, Hans Eriksson, MD PhD MBA, dives into precision medicine's applications in psychiatry in his most recent Psychology Today byline. Learn more about precision psychiatry's transformative journey: #PrecisionMedicine #PersonalizedHealthcare

🎙️ New Podcast Alert: "Frontiers of the Mind: Dr. Tiago Reis Marques on Transforming Psychiatry and Pioneering CNS Therapeutics" 🧠 We are excited to share our latest episode of the Life Science Success Podcast, where we dive deep into the world of neuroscience and mental health innovation with Dr. Tiago Reis Marques, CEO of Pasithea Therapeutics. With a passion that bridges psychiatry and biotechnology, Dr. Marques is at the forefront of developing groundbreaking treatments for central nervous system (CNS) disorders. 🔬 In this engaging conversation, we explore: The journey from academia to leading a biotech venture. The unique approach Pasithea Therapeutics takes in addressing unmet needs in CNS disorders. Insights into neurofibromatosis type one and the innovative treatments in development. The pivotal role of precision psychiatry and personalized medicine in transforming patient care. Dr. Marques's vision for the future of mental health treatment and the potential impact on patients worldwide. Whether you're a professional in the life sciences, interested in the latest in mental health research, or curious about the intersection of technology and healthcare, this episode is packed with enlightening discussions and visionary perspectives. 👉 Listen now to get inspired by the potential of science and innovation to change lives. Don't forget to like, share, and comment with your thoughts! #Neuroscience #MentalHealthInnovation #Biotechnology #PrecisionPsychiatry #HealthcareInnovation #Podcast #LifeSciences https://lnkd.in/geFR2adn

Delving into the fascinating world of #translational research in #neurology and #psychiatry! From #Alzheimer’s disease to neural regeneration, explores cutting-edge methods! Let’s bridge science and medicine! @MDPIOpenAccess @Cells_MDPI

Could epigenetics be the missing link in the rapid and sustained therapeutic improvements elicited by rapid-acting antidepressants such as psychedelics and ketamine? Our new perspective article just published in Translational Psychiatry explores this timely research question, suggesting that while preliminary, the available evidence points in this direction! https://lnkd.in/dgziiaND

Going Full Circle in Precision Psychiatry - Hans Eriksson, MD PhD MBA, CMO at HMNC Brain Health writes about navigating the path of precision into modern psychiatry for Psychology Today https://lnkd.in/e4PxqGaK

Delving into the fascinating world of #translational research in #neurology and #psychiatry! From #Alzheimer’s disease to neural regeneration, explores cutting-edge methods! Let’s bridge science and medicine! @MDPIOpenAccess @Cells_MDPI

Delving into the fascinating world of #translational research in #neurology and #psychiatry! From #Alzheimer’s disease to neural regeneration, explores cutting-edge methods! Let’s bridge science and medicine! @MDPIOpenAccess @Cells_MDPI

📃Scientific paper: Stress-related cellular pathophysiology as a crosstalk risk factor for neurocognitive and psychiatric disorders Abstract: In this narrative review, we examine biological processes linking psychological stress and cognition, with a focus on how psychological stress can activate multiple neurobiological mechanisms that drive cognitive decline and behavioral change. First, we describe the general neurobiology of the stress response to define neurocognitive stress reactivity. Second, we review aspects of epigenetic regulation, synaptic transmission, sex hormones, photoperiodic plasticity, and psychoneuroimmunological processes that can contribute to cognitive decline and neuropsychiatric conditions. Third, we explain mechanistic processes linking the stress response and neuropathology. Fourth, we discuss molecular nuances such as an interplay between kinases and proteins, as well as differential role of sex hormones, that can increase vulnerability to cognitive and emotional dysregulation following stress. Finally, we explicate several testable hypotheses for stress, neurocognitive, and neuropsychiatric research. Together, this work highlights how stress processes alter neurophysiology on multiple levels to increase individuals’ risk for neurocognitive and psychiatric disorders, and points toward novel therapeutic targets for mitigating these effects. The resulting models can thus advance dementia and mental health research, and translational neuroscience, with an eye toward clinical application in cognitive and behavioral neurology, and psychiatry. Continued on ES/IODE ➡️ https://etcse.fr/dsPYj ------- If you find this interesting, feel free to follow, comment and share. We need your help to enhance our visibility, so that our platform continues to serve you.

Embark on a mind-expanding journey with our latest #editorial 🧠✨! Dive into the depths of #neuroscience and discover how cutting-edge research is unlocking the secrets of the #brain 🗝️🧬. From #neuroplasticity to non-invasive brain stimulation, explore the innovations shaping the future of #neurology and #psychiatry 🚀💡 @Biomed_MDPI @MDPIOpenAccess #Neuroscience #BrainHealth #Innovation https://lnkd.in/dFzyuWxp