Christopher Eisenhart’s Post

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Senior Bioinformatics Engineer

Fragmentomics is a wonderful concept in liquid biopsy. Similar to a muti-omics solution, fragmentomics looks at the composition of cf-DNA (length profile traditionally) to identify the ct-DNA profile. From here you can infer all sorts of useful information about the patients cancer. What makes it different from multi-omics is that you use the same DNA assay as for standard liquid biopsy. So twice the bang for a single buck! Seems like most ct-detection projects will soon be adding this to their arsenal. Up next, how to merge fragmentomics analysis with traditional variant calling? Im sure somebody's done it already...!

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