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A 12-year-old Swiss biotech seeks to make its mark in the space of anti-tau Alzheimer's medicines, and it's moving ahead in the same niche as the field's two biggest drugmakers: Eli Lilly and Biogen. With a $100 million Series C, Asceneuron hopes to prove that an O-GlcNAcase (OGA) inhibitor can help thwart or slow down cognitive declines and do so with an oral treatment, rather than complex and healthcare-straining infusions. “Lilly will hopefully validate this class later on this year, and then we are second after that in a very large market,” Naveed Siddiqi said in an interview with Endpoints News. The Novo Holdings venture investments senior partner said it’s believed that tau is “more highly correlated with the loss of your cognition than amyloid is.” More from my interview with Asceneuron SA's CEO Barbara A. and Ryan S.: #alzheimers #tau #dementia #alzheimersresearch #drugdevelopment #ogainhibitor #biotech #venturecapital

#fundingalert 💼Company: Neurenati Therapeutics  💰Funding: $1.2Million ⚡Round: Seed 👥Investors: Genson Capital Neurenati Therapeutics was founded by Nicolas Pilon, Rodolphe Soret.  The funding will be used by the company to expedite the development of NEU-001. A cutting-edge #biotechnology startup called Neurenati Therapeutics is creating a novel therapy for Hirschsprung’s illness. The company is dedicated to getting this treatment into clinical practice and has the backing of multiple #medical professionals, including #gastroenterologists and experts in clinical trials on rare disorders. Maxime Ranger Zhizi Zhao Benoit Dore Alexandre LeBeaut François Boutin, CPA Read more - https://lnkd.in/grySxF9a To share your startup story write us on - contact@startuprise.io #neurenatitherapeutics #biotechnology #meditech #news #healthtech #funding #startup

🚀 Exciting Update! Our startup MyRNAAP (MyRNA) is in the development phase, crafting innovative bioinformatics and AI solutions for RNA-based therapies. Currently, we're focusing on harnessing plant-origin microRNAs to tackle various diseases. 🔍 We need your valuable input! Please take a moment to complete and share our survey within your network. Your feedback, especially from experts in pharmaceuticals and biotechnology, will shape our future endeavors. Survey Link: https://lnkd.in/dXdyA9tr Thank you for your support! For any questions or suggestions, feel free to reach out directly. #Bioinformatics #AI #RNAtherapies #MarketResearch #HealthcareInnovation #Pharma #Biotech #StartupJourney #innovation #pharma #RNA #MyRNAAP (MyRNA) #Startup #tech #PMR

Check out our latest publication in "Progress in Retinal and Eye Research." Titled "Investing in vision: Innovation in retinal therapeutics and the influence on venture capital investment," the article is authored by Partner Dr. Dmitrij Hristodorov, Senior Associate Tim Lohoff, Ph.D., General Partner Nanna Lüneborg, Managing Partner Geert-Jan Mulder, and Advisor Simon J. Clark. The article provides a comprehensive review of the past two decades, covering achievements, challenges, and contextualizing investments, partnerships, and acquisitions. It concludes with an optimistic outlook and potential roadmap for novel retinal therapeutics, emphasizing the potential to stimulate further venture capital investments for the development and delivery of new therapies to patients in need. Access the full article by clicking the link below on our website. #RetinalTherapeutics #MedicalAdvancements #InnovationInHealthcare #VentureCapital #EyeHealth #Research #Publication #lifesciences #biotech

🚀 Exciting Update! Our startup is in the development phase, crafting innovative bioinformatics and AI solutions for RNA-based therapies. Currently, we're focusing on harnessing plant-origin microRNAs to tackle various diseases. 🔍 We need your valuable input! Please take a moment to complete and share our survey within your network. Your feedback, especially from experts in pharmaceuticals and biotechnology, will shape our future endeavors. Survey Link: https://lnkd.in/dXdyA9tr Thank you for your support! For any questions or suggestions, feel free to reach out directly. #Bioinformatics #AI #RNAtherapies #MarketResearch #HealthcareInnovation #Pharma #Biotech #StartupJourney #innovation #pharma #RNA #MyRNAPP #Startup #tech #PMR

𝐍𝐯𝐞𝐥𝐨𝐩 𝐓𝐡𝐞𝐫𝐚𝐩𝐞𝐮𝐭𝐢𝐜𝐬 𝐋𝐚𝐮𝐧𝐜𝐡𝐞𝐬 𝐭𝐨 𝐑𝐞𝐯𝐨𝐥𝐮𝐭𝐢𝐨𝐧𝐢𝐳𝐞 𝐆𝐞𝐧𝐞𝐭𝐢𝐜 𝐌𝐞𝐝𝐢𝐜𝐢𝐧𝐞 𝐃𝐞𝐥𝐢𝐯𝐞𝐫𝐲 Nvelop Therapeutics Nvelop Therapeutics, a biotech company, announces its launch to develop advanced genetic medicines for various diseases. CEO Jeff Walsh highlights the company's potential to overcome challenges in delivering therapeutic cargoes efficiently to target cells. Nvelop's platforms, based on validated approaches from the Broad Institute and Massachusetts General Hospital, promise: Enhanced delivery efficiency Improved tissue specificity Diverse cargo delivery Safety advantages Chief Scientific Officer Melissa Bonner Melissa Bonner expresses excitement for the company's disruptive potential. Founded in 2022 with $100 million initial funding, Nvelop is supported by experienced scientists and industry leaders committed to innovation and excellence. #GeneticMedicine #TherapeuticDelivery #Biotechnology #Startup #Launch #GeneTherapy #CellTherapy #Genomics #Bioengineering #DrugDelivery #PrecisionMedicine #ScientificAdvancement #Investment

💸 IPOs are back with nearly $700M raised in a single day! Recent biotech IPOs from Bicara, Zenas, and MBX Biosciences collectively raised nearly $700M, signalling renewed investor confidence. Bicara raised $108M to advance immuno-oncology therapies, while Zenas secured $198M for autoimmune treatments. MBX Biosciences, developing hormone-based therapies, raised $236M. As 2024 shows increasing interest in the public markets, biotech companies are taking advantage of the window. However, experts remain cautious about the sustainability of this surge amidst regulatory challenges and market fluctuations. Prior to Thursday, the last time three biotechs went public in the same week was in early February, when cell therapy developer Kyverna Therapeutics, gene editing company Metagenomi and anti-aging startup Telomir Pharmaceuticals raised about $420 million over two days. There is a backlog of startups that are relying on later funding rounds to stay afloat and wait for the right opportunity. Their arrival onto the market may be delayed by U.S. elections in November and uncertainty around interest rates, however. “We don’t anticipate a rapid recovery until the dust settles on macro uncertainties, but expect to see an uptick in companies going public in early ’25,” wrote Jefferies analyst Michael Yee in an investor note this summer. #Biotech #IPO #HealthcareInnovation #Investment #Biopharma

Check out this article with Andrew Dunn at Endpoints News covering the launch of biotech startup Insamo. Thanks for speaking with CEO Timothy Craven, PhD and our own Matt Hershenson about how macrocyclic peptides can transform drug discovery as we know it! 💊💊💊

This is optimal.

#fundingalert 💼Company: Diagonal Therapeutics 💰Funding: $128Million ⚡Round: Series A 👥Investors: Atlas Venture, Lightspeed, RA Capital Management, Frazier Life Sciences, Viking Global Investors, Velosity Capital, and Checkpoint Capital, LLC. Diagonal Therapeutics is a biotech company pioneering a new approach to discovering and developing agonist antibodies. The Company’s DIAGONAL platform combines proprietary computational and experimental techniques to overcome historical challenges associated with agonist antibody drug discovery. The financing will support further advancement of the company’s proprietary DIAGONAL platform and pipeline of novel therapeutics to value-creating milestones, including its lead program for the treatment of hereditary hemorrhagic telangiectasia (HHT). Alexey "Alex" Lugovskoy Michael Gladstone Timothy Reilly, PhD Aysheh Alrfooh Monika Sharma Sandra Teixeira Read more -https://lnkd.in/gN9VfBFr To share your startup story write us on - contact@startuprise.io #DiagonalTherapeutics #biotech #biotechstartup #developing #techniques #computational #funding #startupnews #fundingnews #news #startuprise