Clinical, Surgery and Medicine Group Journals’ Post

#mostcited 🏆Recommending One of Our Most Cited Reviews in 2022 Q1！ 📚Gut Microbiota and Short Chain Fatty Acids: Implications in Glucose Homeostasis 🔗https://lnkd.in/gCR4mcin 👨🔬By Prof. Piero Portincasa et al. Università degli Studi di Bari Aldo Moro Albert Einstein College of Medicine Ludwig-Maximilians-Universität München #molecular #endocrinology #metabolism #intestine #bacteria #metabolome #fiber #diet #glucosehomeostasis

It is a great pleasure to be able to share with all of you my second article, carried out during my doctoral thesis, recently published in the International Journal of Molecular Sciences MDPI. Extracellular vesicles (EVs) from beneficial gut microbes are emerging as potential postbiotics. Serotonin plays a crucial role in intestinal homeostasis, and its dysregulation is associated with IBD severity. Our study investigated the impact of EVs from the probiotic Nissle 1917 (EcN) and commensal E. coli on intestinal serotonin metabolism under inflammatory.  Thanks to all the team that made it possible Sergio Martínez, Manel Bosch, Laura Baldomà, Cecilia Cordero & Josefa Badia. #gutmicrobiota #postbiotics #extracellularvesicles #inflammatoryboweldisease #intestinalbarrier #microbiota #microbiology #serotonintransporter #miR24 #miR200a. You can find full access to the article here: https://lnkd.in/d3DHf6ne

🔬🐖 New Insights into Porcine Intestinal Physiology! 🐷🧬   Our recent study dives into this fascinating topic, focusing on differences in nutrient uptake between ileum and jejunum in both female and castrated male finishing pigs.   You can access our latest publication in the Italian Journal of Animal Science titled: Electrogenic transport of amino acids and glucose differs between jejunum and ileum of female and castrated male finishing pigs. Full article: https://lnkd.in/d5QiAApF Co-authors: Marco Tretola, Giuseppe Bee, Paolo Silacci Key Findings: The ileum proved to be a critical site for amino acids and D-glucose absorption, irrespective of gender. Additionally, we observed differences in L-arginine uptake, with females demonstrating a significant increase compared to castrates.

#citation New research sheds light on the impact of aspirin on gut health. 🌟 A study on Cell Host & Microbe from The First Affiliated Hospital of Xi'an Jiaotong University using clinical cohorts and mouse models found that aspirin suppresses the growth of a specific gut microbe, Parabacteroides goldsteinii. Supplementing mice with this microbe or its metabolite, 7-keto-lithocholic acid (7-keto-LCA), reduced aspirin-induced damage to the intestinal barrier. Findings suggest that 7-keto-LCA promotes intestinal epithelium repair by suppressing signaling through the farnesoid X receptor (FXR), highlighting the complex interplay between aspirin, gut microbiota, and gastrointestinal homeostasis. Read more here: https://lnkd.in/gazBpena Cyagen takes pride in its contribution to this groundbreaking study with our Nr1h4=flox [Fxrᶠˡ/ᶠˡ] and PVillin-Cre mice🐭Explore our Cyagen knockout catalog models here: https://lnkd.in/gqxybj-x #gutmicrobiome #guthealth #researchexcellence #research #researchimpact #science #scienceofreading #sciencecommunication #biotechnologie #biotech #biotechinnovation #mouse #aspirin

https://lnkd.in/gNMcY5Bc Article title: Dietary molybdenum may stimulate the growth of colonic sulfur reducing bacteria, increasing hydrogen sulfide levels in the human colon and the possible health effects of an excess of colonic sulfides   Author(s): Brian James Grech   Journal: Archives of Clinical Gastroenterology   Journal ISSN: 2455-2283 Abstract: Molybdenum is a trace mineral needed in small quantities by most life forms. In living organisms, a molybdenum atom is found within molybdenum-dependent enzymes or molybdoenzymes. Molybdoenzymes catalyze reactions in carbon, sulfur, and nitrogen metabolism. Only four molbdoenzymes have been identified in humans. Most of the known molybdoenzymes are found in bacteria. Dietary molybdenum can be administrated to humans, to treat Wilson disease and tungsten poisoning; and it may be useful in arthritis. Sulfur-reducing bacteria are the bacterial group that reduces certain sulfur molecules to hydrogen sulfide. #HydrogenSulfide #InflammatoryBowelDisease #IrritableBowelSyndrome #Molybdenum #SulfurReducingBacteria #Thiosulfate #ThiosulfateDithiolSulfurtransferase #InflammatoryBowelDisease #FunctionalGIDisorders #GastrointestinalAndLiverDisease #DigestiveOncology #GastrointestinalSurgery #PediatricGastroenterology #ColorectalCancer #PancreaticCancer #HepatocellularCarcinoma #GastrointestinalBleeding #Endoscopy #Peertechz #PeertechzPublications #SurgicalGastroenterology #StomachUlcers #VirtualColonoscopy #GastricUlceration #RouxenYGastricBypass #GastricAcidSecretion #GastricMucosa #GastricUlcerHealing #GastricCardiaCancer #ReproductiveEndocrinology #EndocrineDisorders #Hepatology #AlimentaryCanal #PancreasCancer

Over the course of this year we will be responding to common microbiome myths! 🔗 https://buff.ly/3OCEOiC #microbiome #health #healthylifestyle #wellness #mentalhealth #science #guthealth #microbiology #gutbrainaxis #gutmicrobiome

How does daily activity affect the gut microbiome? We sat down with Dr. Lawrence Kosinski, gastroenterologist, founder of SonarMD and Jona’s Chief Medical Officer, to answer this exactly, and learn more about how he uses microbiome science in his own practice. We are excited to continue sharing with you snippets of the interview over the next few weeks. Stay tuned! Continue learning via the Jona website about how you can get your hands on a test kit, https://lnkd.in/gdx8Tsd8. #guthealth #leakygut #guthealing #guthealthmatters #wellness #ibs #ibsdiet #probiotics #ibsawareness #gutmicrobiome #healthygut #digestivehealth #microbiome #digestion #holistichealth #foodismedicine #probiotic #probioticsupplements #gutfriendly #microbiomescience #microbiology

Hesperidin- Important Bioactive From Plants! Hesperidin is a flavonoid that is commonly found in citrus fruits, particularly in the peels and membranes of oranges and lemons. Among its possible health benefits: ·     Antioxidant Properties ·     Anti-Inflammatory Effects ·     Cardioprotective ·     Blood Vessel Health ·     Immune System Support   ·     Neuroprotective Effects ·     Anti-Cancer Potential ·     Antiviral Activity ·     Anti-Allergic Effects ·     Skin Health The main area of interest for Hesperidin seems to be for its use in inflammation or conditions where inflammation is playing a key role, especially due to its combination of anti-inflammatory and antioxidant activities. Hesperidin’s anti-inflammatory activity has been observed in a number of models and physiological processes and it shows promise for benefitting cardiovascular health, neurological health, psychiatric mechanisms, lipid-lowering and insulin-sensitizing, among other uses. Research has indicated that Hesperidin enhances activities of other antioxidants and enzymes, and has been combined with other nutrients in clinical research. For example, combined with calcium it may help preserve bone health in postmenopausal women. #bioactives #medicinalplants #phytochemicals #ethnobotany #hesperidin

Find out more about the #ECE2024 Symposium 10 ‘Bone and muscle vitamin replacement’ which our Calcium and Bone representative is most looking forward to: “While vitamin D is centrally important in bone and muscle physiology and disease, there remains healthy debate and controversy around classical and non-classical actions of vitamin D and wider benefits of vitamin D supplementation. Furthermore, there is growing interest, but some conflicting data, on vitamin K and its actions in bone and muscle. This session promises to provide fascinating insights, from world authorities, into the importance of supplementation of vitamin D and vitamin K with a particular focus on bone and muscle.” - Neil Gittoes, Programme Focus Area Representative, Calcium and Bone Find out more: https://lnkd.in/epsdd_uM #endocrinology #OurEndocrineCommunity #BecauseHormonesMatter

Menthol- Important Bioactive From Plants! Menthol is a cyclic monoterpenoid found in mint (Mentha) species responsible for the minty taste of peppermint oil. It is known to have local anesthetic and weak k-opiod receptor agonist activity. Among its possible health benefits: ·     Pain Relief ·     Irritable Bowel Syndrome (IBS) ·     Antibacterial ·     Cold Symptoms ·     Antioxidant ·     Cancer ·     Anti-obesity ·     Antiinflammatory ·     Antidiabetic ·     Cardioprotective Excitingly, a number of clinical trials have found peppermint oil (which contains menthol) to be useful for the cramping, pain, and other symptoms of irritable bowel syndrome (IBS). A meta-analysis of pooled clinical data involving 12 randomized trials with 835 patients found peppermint oil to be safe and effective for the pain and global symptoms in adults with IBS. #bioactives #medicinalplants #phytochemicals #ethnobotany #biodiversity #menthol *This content is for informational and educational purposes only. It is not intended to provide medical advice or to take the place of such advice or treatment from a personal physician.