CN Bio ’s Post

#NGS anticipates a 13% annual growth, propelling the global #NGS manufacturer market from $6.5 billion to $9.4 billion by 2026. The market was poised for resurgence in 2024, foreseeing substantial growth in #clinicalapplications, steering mid-teen market expansion in 2025 and 2026. Driving forces for growth encompass heightened adoption in #clinicalsettings, increased reagent utilization, and the proliferation of applications like #singlecell #RNASeq and #methylation analysis. Amidst promising trends, challenges loom, including excess #capacity, #pricing pressures, #reimbursement uncertainties, and #regulatory constraints. The forthcoming 3 years are poised to spotlight Illumina, Oxford Nanopore Technologies, PacBio, and MGI /Complete Genomics. Illumina's dominance is accentuated by #reliability and ecosystem #support, while Oxford Nanopore Technologies and PacBio surge ahead with #longreads and supplementary information. MGI/Complete Genomics garners attention for its #comprehensive solutions, while Element Biosciences, Singular , and Ultima Genomics emerge as notable competitors in the #shortread domain. #ngs #genomics #worldwide #competitiveintelligence #marketshare #marketdynamics

Managing a highly curated small molecule library isn’t just science, it’s an art — one that’s powered by automation, innovation, and attention to detail. 🎨🔬 At the XXVIII EFMC International Symposium on Medicinal Chemistry, Laura Mangiardi, Principal Research Scientist at IRBM, shared insights into our fully automated platform for compound collection management for High Throughput Screening. This platform addresses the growing complexity and size of compound libraries, which have expanded significantly with advancements in chemistry and medicinal design, underscoring the need for more efficient and scalable end-to-end management solutions in drug discovery. 💡Don’t miss this edition of “𝗗𝗶𝘀𝗰𝗼𝘃𝗲𝗿𝘆 𝗕𝗶𝘁𝗲𝘀” by IRBM, and mark your calendars for the upcoming SLAS (Society for Laboratory Automation and Screening) 2024 Sample Management Symposium to learn more about how we’re speeding up the discovery of new therapeutics by adding efficiency, accuracy, and scalability to every step of the process. #EFMC2024 #DrugDiscovery #MedicinalChemistry #IRBM

We are thrilled to announce the addition of five 1-day symposia added to the #CHIPepTalk program lineup. Each symposium is crafted to align with our overarching pipeline theme, providing a unique opportunity to delve into critical technical nuances that are often overlooked. ▶ Learn more https://lnkd.in/geNt5Cwh Led by esteemed researchers and thought leaders, these symposia feature interactive discussions, panel talks, and podium presentations. You can tailor your agenda by pairing a symposium with conference tracks or training seminars, creating a 4-day itinerary that caters precisely to your professional interests. Symposia Include: (Re)Discovering Protein Expression Platforms Predictive Protein Production Machine Learning and Predictive Methods in Analytical Development Vectors for Targeted Delivery Bispecific Engineering & Therapeutics

In collaboration with Matthew Disney at The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology, we used our groundbreaking MFS technology to investigate the interaction between the protein Dicer and the pre-microRNA, pre-miR-21. 📈 Using our platform, we applied slow ramps in force, increasing over time until pre-miR-21 became linearized. 🔄 We repeated the experiment, but this time with the protein Dicer bound to pre-miR-21. 📊 Raw data showed that Dicer increases the force required to linearize the RNA strand - by about 6 pN of force. 🏋️♂️ This showed us that the RNA-binding protein Dicer stabilizes the structure of pre-miR-21. 🔬 We then tested a number of drug candidates, one of which significantly inhibited Dicer : pre-microRNA21 binding. 💡 In this way, our MFS platform can unveil the dynamics of RNA-protein interactions - and help you identify drug candidates that alter biomolecular interactions. If you could directly measure the strength of biomolecular interactions, what would you explore? #RNATherapeutics #DrugDiscovery #Biotech #Interactomics

🚀 Exciting New Tool for Researchers! 🚀 Choosing the right microplate reader for your lab just got a whole lot easier. 🎯 Our interactive experience is designed to help you find the perfect solution based on your specific research needs. Whether you're in academia, biotech, or pharma, we know every lab has unique requirements—and now you can chart your own course to the best fit! ✅ Answer a few simple questions about your applications ✅ Get matched with the ideal SpectraMax® Microplate Reader ✅ Access additional resources and request a quote directly Explore the tool here and see how easy it is to streamline your lab's workflow: https://lnkd.in/gV8DB7_P #LifeSciences #MicroplateReader #Biotech #Pharma #LabTech #ResearchInnovation #InteractiveExperience #MolecularDevices #LabSolutions

Two important topics that are near and dear to us at BioIVT will be explored in-depth at #ASGCT2024 this week. We’re always striving to match researchers with the right test system for their research to help ensure accuracy. To that end, Karissa Cottier, PhD will be presenting #scientificposter 727 on Wed. afternoon on the in vitro assessment of GalNAc-conjugated siRNA cellular uptake and target knockdown in primary human #hepatocyte culture models: https://hubs.ly/Q02w7L2T0 And just as relevancy can greatly impact research and development outcomes, logistics plays a critical role in the quality of #biospecimens by the time they reach the hands of researchers, which is why we work so hard to secure our supply chain. As part of our commitment to quality, Diana Chiluiza, PhD will be presenting poster 1371 on Thurs. afternoon analyzing the impact of temperature conditions on cell stability in #leukopaks during shipping: https://hubs.ly/Q02w7Kj60 Make sure to stop by booth 1037 to connect with our expert team, including Parijat Jain PhD, Christopher Reed, Joshua Taylor, Brianna Van Ness and Timothy Moeller, to discuss securing a RUO + GMP provider for #CellandGeneTherapy cellular starting materials, finding the right biospecimens for your needs, understanding the #ADME properties and risks of your therapeutic, and more! #CellTherapy #GeneTherapy

How can  DNA Encoded Libraries (DEL) and Micromapping Technology advance targeted and precise therapeutics? Check this interesting Webinar to learn more.

DNA-encoded library (DEL) technology accelerates drug discovery by using vast libraries of tiny molecules, each tagged with DNA for rapid identification and sorting. Enhanced with dynamic libraries, a path-coding algorithm, binding profiler validation, and MicroMapping for precise spatial analysis, this approach streamlines the search for new medicines. Learn more in this on-demand webinar.

DNA-encoded library (DEL) technology accelerates drug discovery by using vast libraries of tiny molecules, each tagged with DNA for rapid identification and sorting. Enhanced with dynamic libraries, a path-coding algorithm, binding profiler validation, and MicroMapping for precise spatial analysis, this approach streamlines the search for new medicines. Learn more in this on-demand webinar.