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Access our on-demand webinar to learn about how scientists are leveraging single-cell epigenomics assays like ATAC-seq, whole transcriptome assays and image-based spectral sorting to drive deep immunology discovery. Watch now: https://bit.ly/3LfsiU6 #epigenomics #transcriptomics #spectralflowcytometry #ATACseq #singlecellmultiomics #BDRhapsody #BDBiosciences

Wondering which proteins are in our Single Cell Proteomics Kit, Immunology Panel I? Check out this document for a complete list and let us know which one interests you the most, and why. #molecularpixelation #proteinlist #pixelgentechnologies #spatialbiology #spatialanalysis #spatialproteomics #proteomics #singlecell #PBMCs #immunologymarkers #cellsurface #surfaceproteins #Kitcontents #immunologypanelI #Humanimmunology

Nuclei Webinar 15 | Exporting In this clip, Ben demonstrates how to easily export results from the CellDrop Automated Cell Counter. "Optimizing Nuclei Extraction & Counting for Single Cell Sequencing" is available to watch on-demand! Watch now: https://buff.ly/45yLYuK #LifeScience #Laboratory #Microbiology #CellBiology #CellCulture #LaboratoryEquipment #Immunology #CancerResearch #FlowCytometry #Webinar

2BScientific has partnered with FUJIFILM Irvine Scientific to distribute Cell Therapy Grade GMP Recombinant Human Proteins, enhancing the reliability and efficiency of cell culture applications crucial for regenerative medicine and cell therapy. These high-quality, GMP-standard proteins support optimal cell growth and proliferation, addressing the challenge of maintaining consistent and high-purity cell cultures. This consistency is vital for researchers in the field of immunology, and results in advancing downstream applications and improving the development of treatments for various degenerative diseases and injuries. Other advantages of FUJIFILM Irvine Scientific's Cell Therapy Grade GMP Recombinant Human Proteins: 🐝Streamlined workflows 🐝Complements PRIME-XV neural cell serum-free media 🐝Supports research from basic to clinical stages 🐝High lot-to-lot consistency for reliable results Trust FUJIFILM Irvine Scientific's 45+ years of expertise and 2BScientific to deliver life-changing research reagents, and check out our full article on FUJIFILM Irvine Scientific’s products here! https://buff.ly/3Ye4wzN #GMP #immunology #lifesciences

Tools: "Here, we introduce a novel in vitro cultivation system based on ThymoSpheres (TS): dense spheroids consisting of DLL4-expressing stromal cells and human hematopoietic precursor cells, in the absence of thymic epithelial cells. These spheroids are subsequently cultured at the air–liquid interphase. TS generate large numbers of mature T cells, are easy to manipulate, scalable, and can be repeatably sampled to monitor T-cell differentiation." #Immunology https://lnkd.in/gnvu5_ai

🔬🧬 Delving into the latest advancements in immunology, the recent publication in Frontiers in Immunology sheds light on how molecular antibody biology and structural protein engineering are revolutionizing the field. The study explores the intricate modifications of IgG antibodies, aiming to boost their therapeutic potential. Key areas include glycosylation, allotypic variation, Fc engineering, and Fc gamma receptor binding optimization. This research is a leap forward in understanding and enhancing the efficacy of antibody-based therapies. 🌐🔍 #Immunology #ProteinEngineering #Therapeutics #AntibodyResearch #Biotechnology Timon Damelang Maximilian Brinkhaus Thijs van Osch Janine Schuurman Aran Labrijn Theo Rispens Gestur Vidarsson

🎉 Congrats to our partners from University College Dublin! In September 2024, our partners, Zhiran Wang and Günther Eißner from UCD, Systems Biology Ireland, participated in the 7th European Congress of Immunology in Dublin. 🔬 One of the highlights of the conference was Zhiran's presentation of her poster on "The Protective Effects of the Fibrin-derived Peptide FX06 on Human Pulmonary Endothelial Cells Against COVID-19-Triggered Cytokines." This poster delved into the research conducted by the UCD team within the COVend project, which focused on the influence of COVID-19-triggered cytokines on pulmonary endothelial cells, particularly in terms of apoptosis/necrosis, immunological activation, and transendothelial permeability. Visit our website and learn more about their research results and COVend project 👇 https://lnkd.in/du9JKPDa #COVend #IXION2 #IXIONClinicalTrial #ClinicalTrial #MedicalResearch #HorizonEurope #HorizonEU #EUproject #ARDS #FX06 #VascularBiology #endothelialcells #cytokines

Cellmatic, the Automated Cell Culture System, is versatile for a wide range of scientific workflows. From automating lengthy protocols to ensuring precise multi-well plating for HT screens, the Cellmatic simplifies your cell research processes. Key applications include: 🧬 Stem Cell Differentiation: Automate week and month-long protocols with thoughtful management of expensive reagents 🧫 Cell Line Development: Pick colonies and propagate forward from 384- and 96-well plates 🔍 Routine Maintenance & Expansion: Continuously feed, image, and passage cell lines with extensive data record keeping 💻 Multi-Well Plating for HT Screens: Dispense cells into 384- and 96-well plates at user-defined cell number 🧪Permeability Assays: Feed and culture cells in transwell plates for your permeability assays 🩸 Immunology Studies: Differentiate and mature blood cells for immunological assays Learn more: https://hubs.ly/Q02QKpBv0 #CellCulture #AutomatedCellCulture #StemCells #Immunology #HTS #Cellmatic #Formulatrix

BCR Signaling Overview👇 📎When antigens bind to B-cell receptors (BCRs) on the surface of B cells, it initiates a signaling cascade within the cell. This process begins with the activation of tyrosine kinases from the SRC family. 📎Activation of ITAMs: The SRC family tyrosine kinases phosphorylate immunoreceptor tyrosine-based activation motifs (ITAMs) located on the cytosolic tails of Igα and Igβ molecules associated with the BCR. 📎Docking of SYK and Further Signaling: The phosphorylation of ITAMs facilitates the docking of SYK (spleen tyrosine kinase) to the BCR complex. This event leads to the tyrosine phosphorylation of additional adaptor proteins. 📎Signal Transduction Cascades: The activation of these adaptor proteins triggers canonical signal transduction pathways involving PLCG2 (phospholipase C gamma 2) and RAS. These cascades culminate in the activation of key transcription factors, including NFAT (nuclear factor of activated T-cells), NFκB (nuclear factor kappa B), and AP1 (activator protein 1). #BCR #bcrsignaling #immunology #cancerbiologyresearch Image: Carsten Carlberg, Eunike Velleuer - Molecular Immunology_ How Science Works-Springer (2022)

"Life's intricate network of choices can be discerned using LOGICAL THINKING (True or False)." Recently, my first research contribution to the domain of "Systems Immunology" was recently published in "npj Systems Biology and Applications" journal. Requesting all to go through the article to utilize its applicability and provide your valuable feedback. I thank my supervisor Prof. Ganesh Viswanathan for his immense guidance and assistance. #springernature #systemsbiology #computationalbiology #boolean #dynamics Link is in https://lnkd.in/dxNc68-G