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How to deal with direct compression challenges: 7 ways to overcome them ✔️Tablet tensile strength and friability can be improved by adjustment of the formulation or process parameters ✔️Flowability can be improved by adjustment of physical properties or by changing the flow field or stress state ✔️Dissolution can be improved by improved disintegration (when this is limiting) or by adjustment of API properties ✔️Content uniformity can be improved by effective dispersion of the API ✔️Robustness of a formulation can be improved by using ingredients that are consistent and have low process sensitivity ✔️Punch sticking can be reduced by increase of the excipient-API interaction or by decrease of the API-punch interaction ✔️Capping or lamination can be reduced by minimizing elastic deformation, via adjustment of the process or formulation Read more about DC Challenges and our specific portfolio: https://lnkd.in/eyJGCSdf Optimal formulation and choice of excipients will depend on the specific situation, we always recommend discussion with our technical experts. Feel free to reach out to them: https://lnkd.in/eEBwjT6X #Excipients #Pharmaceuticals

Polysorbate 80 / Polyoxyethylene (80) sorbitan monooleate Polysorbate 80 is a versatile chemical commonly used in a variety of industries. It serves as a surfactant in soaps and cosmetics, a lubricant in eye drops, and an emulsifier in food and pharmaceutical products. In skincare, Polysorbate 80 is considered safe and is often utilized as an emulsifier to effectively blend oil and water. Its multifunctional properties make it a valuable ingredient in many products, ensuring optimal performance and quality. Contact 📧 : mauli@advancedenergychem.com Visit : https://lnkd.in/gjjNWF-s #Polysobate80 #Polyoxyethylenesorbitanmonooleate #AdvancedEnergyChem #Emulsifier #Surfactant #ChemicalSourcing #CosmeticChemical #Dyes #Pigments #AcidDyes #SolventDyes #Neutraceuticals #LiquidDyesforPaper #FoodColours #LakeColours #FDandCColours #FlavorsandFragrance #Intermediates #AgroChemicals #WaterTreatmentChemicals #Pharmaceuticals #PersonalCare #Detergents

What are excipients? Types of excipient that are used during formulation of medicinal product? Excipients are inactive substances added to pharmaceutical formulations to enhance stability, bioavailability, or facilitate the manufacturing process. They play a crucial role in drug delivery, helping to shape the dosage form and improve the overall characteristics of the medication. Common types of excipients include: 1. Binders: Enhance tablet integrity by promoting particle adhesion. 2. Fillers or Diluents: Provide bulk to formulations and ensure proper tablet size. 3. Disintegrants: Aid in tablet or capsule breakdown for better drug release. 4. Lubricants and Glidants: Reduce friction during tablet compression and improve flow properties. 5. Flavors and Sweeteners: Improve taste and palatability of oral medications. 6. Colorants: Enhance appearance and aid in product identification. 7. Preservatives: Extend shelf life by preventing microbial growth. 8. Surfactants: Enhance solubility and stability of poorly soluble drugs. 9. Coating Agents: Protect the drug from environmental factors and control release. 10. Antioxidants: Prevent degradation of drug molecules due to oxidation. These excipients, when combined with active pharmaceutical ingredients, contribute to the overall safety, efficacy, and patient acceptability of medicinal products. Stay Tuned Abu Talha B. #excipients

🔍 Understanding Nutraceutical and Pharmaceutical Packaging 🔍 Packaging is a critical aspect of ensuring the safety, efficacy, and shelf life of medications. When it comes to packaging capsules and tablets, choosing the right method is essential. Let’s dive into some insights: Primary Packaging: Bottles: Bottles are versatile and commonly used for packaging tablets, capsules, gummies, and other solid dosage forms. They come in various materials (plastic or glass), colors, and sizes. Bottles protect the contents from moisture, pests, and physical damage. Secondary Packaging: Cartons: Secondary packaging, like cartons, provides an extra layer of protection. Customizable cartons not only safeguard primary packaging but also allow you to showcase your brand identity. Why It Matters: Safety: Proper packaging prevents contamination, maintains chemical composition, and ensures product integrity. Regulations: Compliance with industry standards and regulations is crucial. Consumer Experience: Convenient, user-friendly packaging enhances the overall experience for patients and consumers. Remember, the right packaging not only preserves your product but also communicates your brand’s commitment to quality. 🌟 #Paxeuticals #NutraceuticalPackaging #PharmaceuticalPackaging #QualityMatters #Packaging Call us: +1 (201) 899-0255 Email: info@paxeuticals.com Web: www.paxeuticals.com

#SamplePreparation processes have not progressed at the same speed as analytical techniques like #chromatography … until now. Check out this video which showcases how Ego Pharmaceuticals – a science-driven skincare company – swapped their labour-intensive sample preparation workflow with the ePrep® ONE. This allowed the company to test every batch of sunscreen they make, ensuring each contains the correct composition of active ingredients, without subjecting staff to tedious manual tasks. Not only does this new workflow produce accurate and reproducible results, but it also leaves their analysts free to perform other tasks. Watch the short video here: https://ow.ly/nr3q50RtbZ5

The filling vacuum capping machine is suitable for various industries, including food, pharmaceuticals, cosmetics, and chemicals. In the food industry, it is commonly used to seal canned foods such as sauces, seasonings, and canned goods. In the pharmaceutical industry, it can be used to seal medicine bottles and containers. In the cosmetics industry, it is used to seal cosmetic bottles and skincare product containers. In the chemical industry, it is used to seal various chemical containers, such as cleaning agents and liquid chemicals.

Exciting News! Introducing Corelease™ - A Breakthrough in Controlled Release Formulated Systems! Today, Colorcon unveils its latest innovation - Corelease™ Controlled Release Formulated Systems, a unified brand that consolidates the company's extensive range of controlled release products. This strategic launch represents a significant milestone in Colorcon's ongoing commitment to advancing controlled release technologies within the pharmaceutical industry. Corelease™ is designed to simplify the development and manufacturing processes for controlled release, offering a cohesive and efficient approach to formulation design. Streamlined Development: Corelease™ systems simplify controlled release development, providing a comprehensive and efficient solution. Read more here: https://hubs.li/Q02bRKlL0 Two Exceptional Coatings: The initial Corelease™ lineup features Corelease EC™, an Ethylcellulose Organic Coating System for sustained release and taste-masking, and Corelease CA™, a Formulated Osmotic Coating System for consistent release from push-pull osmotic pump (PPOP) tablets. This strategic initiative reaffirms Colorcon's position as an industry leader, dedicated to providing comprehensive solutions that drive efficiency, reliability, and success in pharmaceutical product development. Learn more: https://hubs.li/Q02bRKlL0 Join us in celebrating, as Colorcon continues to shape the future of controlled release technologies. #Colorcon #Innovation #Pharmaceuticals #ControlledRelease #Corelease #HealthcareInnovation

Talc, a multifaceted ingredient commonly utilized in pharmaceutical formulations, plays a pivotal role in enhancing product quality and efficacy. ✅ Lubricant & Diluent: In tablet formulations, talc serves as a lubricant and diluent, refining the flow properties of powder mixtures, and ensuring easy swallowing of tablets. ✨ Glidant: Its application as a glidant in capsule formulations improves the flow of powder into capsules, streamlining manufacturing processes. ⚖️ Bulk Enhancer: Talc provides essential bulk to powders, guaranteeing they fill containers, and optimizing packaging efficiency. 🔄 Friction Reduction: By reducing friction between particles, talc prevents clumping or caking, maintaining powder consistency and facilitating uniform mixing. 🚫 Health Considerations: While talc offers numerous benefits, it's crucial to mitigate risks associated with inhalation of talc dust, which can lead to respiratory issues. #Pharmaceuticals #Talc #Formulation #QualityAssurance #Healthcare #Innovation Photo; CNBC (read the whole story here; https://lnkd.in/dZ_y4mBp)

📚 Tablets Excipients in Pharmaceutical Formulation ▶ Tablets contain not just the active drug, but also various #excipients that play crucial roles ▶ Excipients are the "inactive" ingredients that make tablets #practical, stable, and effective. ▶ Key excipients include diluents/fillers, binders, disintegrants, lubricants, and more - each with specific #functions. 💠 The Art of Choosing Excipients ▶ Selecting the right excipients is a delicate balance, considering factors like safety, stability, #compatibility, and cost. ▶ Commonly used diluents include lactose, starches, cellulose, and calcium salts - each with #unique pros and cons. ▶ Binders hold the tablet together, while disintegrants help it break apart in the body. #Lubricants ease the manufacturing process. 💠 Enhancing Tablet Experience ▶ Colorants, flavors, and sweeteners can make tablets more visually appealing and palatable, especially for #pediatric and geriatric patients. ▶ Co-processed excipients combine multiple ingredients to optimize properties and simplify #formulations. 👉 Follow Pharma Broadcast and Henry for more #Pharmaceuticals #Tablets #Excipients #Formulation #Development #Ingredients