CovalX’s Post

NEW IN LYME TESTING: Unlike the traditional two-tier testing for Lyme disease, which is known to lack sensitivity and be inaccurate, a new single-tier Lyme test could potentially deliver accurate results in under 20 minutes. The test utilizes a paper-based platform combined with synthetic peptides that target specific antibodies found in patients' blood. By employing a machine learning-based diagnostic model, the test was able to achieve 95.5% sensitivity and 100% specificity in identifying positive and negative samples from the Bay Area Lyme Foundation Disease Biobank (LDB). While more research is needed, improved diagnostics for Lyme and other tick-borne diseases may be on the horizon. Check out the science via Nature Portfolio: https://lnkd.in/gxZKjfdR #projectlyme #lyme #tickbornediseases #coinfections #lymediseaseawareness #health #tickbite #medicine #chroniclyme #diagnostics #testing #treatment #science #research

8 Renal Function Kit is a special kit for testing kidney function of Seamaty fully automatic dry biochemistry analyzer #SD1. It also includes blood sugar and individual ion items; it can be used in chronic disease management, prognosis diagnosis, and medication observation. Click the link to get more info: https://lnkd.in/djYwJzKK #reagents #biochemistryanalyzer #pointofcaretesting #invitrodiagnostics #medicaldiagnostics

Diagnosis and Treatment Listeriosis Diagnosis Listeriosis is usually diagnosed when a bacterial culture (a type of laboratory test) grows Listeria from a body tissue or fluid, such as blood, spinal fluid, or the placenta. Treatment Invasive illness: People with an invasive illness are treated with antibiotics. Learn more about the treatment of people who have an invasive illness or who have a greater chance of developing one > Intestinal illness: Most people recover from intestinal illness without antibiotic treatment. Antibiotics are needed only for patients who are very ill or at risk of becoming very ill. People who have an intestinal illness should drink extra fluids while they have diarrhea. https://lnkd.in/gatiwuz9

Explore the role of bile acids in staging liver fibrosis in nonalcoholic fatty liver disease (NAFLD) with this latest study! Discover how serum bile acid levels, combined with clinical markers, accurately predict mild fibrosis in diverse populations. Read more about the promising findings here: https://ow.ly/zIAj50SBNjK #NAFLD #LiverFibrosis #BileAcids #MedicalResearch #UCSD #UCSanDiegoHealth

For patients with recurrent urinary tract infections and patients needing long-term catheter use to manage urinary problems, biofilms formed by bacteria can be a problem and are difficult to treat. New compounds that mimic carbohydrates, called glycomimetics, have shown promise in inhibiting these bacteria and the biofilms they form. More research on these compounds is needed before they can be used to treat patients. Check out our new release: Glycomimetics as Candidates for Treatment and Prevention of Catheter-associated Biofilms Formed by Pseudomonas aeruginosa. Eur Urol Focus 2024 Sep 6:S2405-4569(24)00167-6. doi: 10.1016/j.euf.2024.08.011 Christian Vogel, Katharina Rox, Florian Wagenlehner , Alexander Titz https://lnkd.in/dAcdbHxw

Did you know aberrant #NLRP3 function has been implicated in multiple inflammatory diseases? Discover in our #TechnicalArticle how three scalable cell-based assays provide new insights into NLRP3’s role in inhibition of functional inflammasome response. https://bit.ly/3vm05Xz

Did you know aberrant #NLRP3 function has been implicated in multiple inflammatory diseases? Discover in our #TechnicalArticle how three scalable cell-based assays provide new insights into NLRP3’s role in inhibition of functional inflammasome response. https://bit.ly/3x2mJVP

What is Hydrops Fetalis? Hydrops fetalis is a condition which is caused in the Alpha thalassemia major disease. In this condition the all normal hemoglobins were absent and the presence of Bart's hemoglobin. Bart's hemoglobin are produced due to the deletion of all four Alpha genes and consequently the infant have nearly 100% of hemoglobin Bart's which only consist of four Gamma-Globin Chains. In the cellulose acetate hemoglobin electrophoresis with alkaline PH reveals one band migrated towards the anode faster than Hb-A. This band will suggest the Hb-Barts, because this impaired Hgb has very high oxygen affinity and useless for oxygen delivery to the tissue due to no Alpha-Globin Chains.

Telitacicept, a promising BLyS/APRIL dual inhibitor for Sjögrens’ disease treatment: 🔹#Telitacicept is a soluble fusion protein composed of the transmembrane activator, calcium modulator, cyclophilin ligand interactor (TACI), and fragment crystallizable (Fc) domain of human IgG.  🔹Telitacicept binds to and neutralizes the activity of #BAFF and #APRIL, two critical factors in the pathogenesis of #Sjögren’s disease. 🔹Telitacicept resulted in a significant reduction in ESSDAI score in patients with Sjögren’s disease in phase 2 trial, showing also good tolerance and safety. 🔗https://lnkd.in/dmNG3t5M