Our lab knows no secrets. We frequently share our methods in blog posts. To make it even more practical, we also share our actual protocols. For sharing our protocols, we love Briefly Bio for their vision of standardizing protocols and their beautiful designs 🫶
Today, we're announcing Research Portfolios. The place to showcase your best lab work. And that other lab work too, that never got it's day in the sun. Your lab notebook is valuable. Contained within it, amongst the scribbles, the coffee stains, and the master mix calculations, are pages and pages of learning. Research Portfolios are your space to share those learnings, whether they made it into a paper or they didn’t. Don’t know what I’m on about? To explain, we’ll be showing you a few Briefly Bio portfolios from our users. You’ll get an insight into their science, and maybe some ideas about aspects of your own research you could share. Today, we’re kicking off with Cradle. Cradle are simplifying protein engineering. Their AI models suggest better sequences for functional objectives. Their in-house lab builds and tests new generations of protein variants, and the data feeds back and improves the next round of predictions. Cradle are doing things differently, in so many ways. Not only in their tech, but also in their values. That includes publicly sharing the lessons they’ve learned. With that in mind, Cradle pulled back the curtain on two of their core wet lab processes, so that others might use and learn from them, sharing their protocols on their Briefly Portfolio: https://lnkd.in/eVhEHsXm. This includes all the details of their high throughput protein expression platform – how they use Enpresso media to produce consistent yields at low volumes, as well as their experience with a mutagenesis technique called Darwin Assembly from Chris Cozens and Vitor Pinheiro. Jinel Shah at Cradle reflected that, “Something as simple as providing this workflow makes it more accessible. We’re trying to change the mentality because a lot of companies think that getting fancy equipment will solve all of their problems,” Cost-effectiveness, practicality, and transparency. Celebrating these qualities in science will help us all move forward faster. Check out their portfolio: https://lnkd.in/eVhEHsXm. #openscience #research #proteinengineering #cradle
Protein engineer | Enzymologist | Luciferasemaster
2moCould depend on a situation 😂: