Curi Bio’s Post

« Cerebrospinal fluid-venous fistulas (CSFVF) are a common cause of spontaneous intracranial hypotension (SIH). Transvenous embolization has emerged as a reliable treatment option. We review the clinical presentation, imaging, and clinical outcomes of 100 consecutive CSFVF patients who underwent embolization over 2 years.» ⬇️⬇️⬇️ Clinical and imaging outcomes of 100 patients with cerebrospinal fluid-venous fistulas treated by transvenous embolization. Brinjikji W, Madhavan A, Garza I, Whealy M, Kissoon N, Mark I, Morris PP, Verdoorn J, Benson JC, Atkinson JLD, Kobeissi H, Cutsforth-Gregory JK. J. Neurointerv Surg. 2024 Jun 27:jnis-2023-021012. doi: 10.1136/jnis-2023-021012. https://lnkd.in/d7S4duyx

Are you struggling with the complexities of developing ophthalmic drug products? You're not alone! Join us for an insightful webinar featuring Dr. Hovik Gukasyan, PhD and Dr. Maxime Le Merdy as they demonstrate innovative solutions using the mechanistic ocular absorption and transit (OCAT™) model in GastroPlus®. Learn how these models can better understand drug partitioning in eye tissues, facilitating the development of safer and more effective ophthalmic products. https://lnkd.in/g7WGNFSC?

Do you work with liquid biopsies? Join the webinar to learn how to streamline your workflow, with particular focus on setting up ctDNA dPCR with dPCR assay controls, replicates, and QC control, strategies for selecting the optimal assay, and the pros and cons of different methods of reporting your data graphically. 📅Register now: https://ow.ly/rW3450RU2p2 #LiquidBiopsies #dPCR #DNAIsolation

Crisp IHC images that Pathologists like :-).

In the current experimental murine models, there are several technical challenges that compromise their performance. These include PD catheter migration and kinking, which often result in earlier catheter removal. As a result, these limitations drive the need for more animals to complete a study. However, we have addressed these drawbacks and introduced technical improvements and surgical nuances to prevent commonly observed PD catheter complications in a murine model. Furthermore, this modified model is validated by inducing peritoneal inflammation and fibrosis using lipopolysaccharide injections. Essentially, this paper describes an improved method to create an experimental model of PD. The study on peritoneal membrane failure began in 2023 with the methodology mentioned above. doi 10.3791/63689.#peritoneal_catheters #Peritoneal_membrane_failure #ultra_filtration #murine_models

Biologics PRP + ESWT combination DataBiologics for shoulders and knees continues as predicted to improve performance and long term outcomes in shoulders and knees Delighted that Storz Medical STORZ MEDICAL AG is a Gold Sponsor BRITISH ASSOCIATION OF SPORT AND EXERCISE MEDICINE Conference Coventry 🗓️ 07 Nov, 4:15 PM 💉 Session: Injectables in Elite Sport: Evidence Base and Experience 🎤 Speaker: Dr Justin Lee In this session, Dr. Justin Lee will explore the growing role of injectables in sports medicine. He’ll address key questions like which injectables are best for specific injuries and what evidence supports their use. Essential for anyone focused on rapid recovery and injury management in elite sports. 🔗 Learn More - https://www.rfr.bz/lmi4ibw 🎟️ Get Tickets - https://www.rfr.bz/lmi4ibx #BASEM2024 #SportsMedicine #EliteAthletes #InjuryRecovery #Injectables #RapidRecovery

Introducing Beaconic 3 Part+ The ultimate solution for accurate and efficient hematology analysis! 🩸💉 🔹 CBC + 3Diff, 21 parameters + 3 histograms: Comprehensive insights into blood samples for precise diagnosis and monitoring. 🔹 Throughput up to 70 Tests/hour: Experience unmatched productivity with faster results and optimized workflow. 🔹 Ultra-modern design with 10.4" TFT touchscreen color display screen with touch panel: Enjoy a seamless user experience with an intuitive interface. 🔹 Sample volume 9µl in whole blood, ideal for pediatric samples: Analyze samples from our little ones with ease and accuracy. 🔹 Large storage capacity of 500,000 results: Manage and access your data effortlessly for efficient record-keeping. 🔹 Cryptic flag information: Say goodbye to guesswork and ensure precise and reliable interpretation of test results. To know more about Beaconic 3 Part+ and revolutionize your hematology analysis, contact us on WhatsApp now! 📲💬 https://wa.me/918488995888 Visit us at: 🌐 https://lnkd.in/d_P4AAnH #BeaconGroup #HematologyAnalyzer #CuttingEdgeTechnology #AccurateDiagnosis #EfficiencyAtItsBest #PediatricFriendly #DataManagement #PreciseResults #beacon #beacondiagnostics

Did you know that doctors can now use #PulsedElectricField (PEF) technology to precisely target lesions while preserving nearby sensitive structures, such as nerves and blood vessels?* Potential benefits of using PEF energy versus thermal ablation may include a consistent ablation size, which is independent of heat sink effects, and preserving the extracellular matrix.** Galvanize is a leader in the energy-based medical device technology space. Learn more at GalvanizeTX.com! #PEF #Aliya #InterventionalOncology #InterventionalRadiology #Immunotherapy #iRAD #MedEd *Internal data on file. TR-00504; Internal data on file. TR-00538 **Internal data on file. TR-00211 Lab 92; Internal data on file. TR-00158 Lab 90; Internal data on file. TR-00504; Internal data on file. TR-00538. The Aliya® System is 510(k) cleared in the United States for the surgical ablation of soft tissue. It is not currently commercially available in any other geography. Galvanize Therapeutics® does not promote the off-label use of its products and nothing herein is intended to promote an off-label use of the Aliya System. The Aliya System is a tool for the surgical ablation of soft tissues, and is not intended to treat, cure, prevent or mitigate any specific disease or condition.

Immunofluorescent Staining Within Hours, Not Days - https://lnkd.in/gzPBgCBM AMSBIO has launched CellO-IF – an all-in-one immunofluorescent staining reagent kit designed to accelerate the labelling organoids and spheroids directly in hydrogels or extracellular matrices, while preserving delicate structures and cellular integrity. Immunofluorescence (IF) allows detection and localization of antigens in diverse types of tissues in various cell preparations. The technique provides excellent sensitivity and amplification of signal by comparison to immunohistochemistry. However, traditional IF staining is a labor intensive, multi-step process. CellO-IF revolutionizes this by streamlining the procedure. Read more at: https://lnkd.in/gzPBgCBM #immunofluorescence #stemcells #organoids Krystyna Joyce Bill Bradbury

We are excited to update that Clexio has initiated a Phase 2 Proof of Concept study, to assess the efficacy and safety of CLE-400 topical gel for the treatment of chronic pruritus in adults with Notalgia Paresthetica. The study is a randomized, double-blind, vehicle controlled multicenter study enrolling in the US.   Notalgia Paresthetica is a type of sensory neuropathy responsible for chronic itch in the upper back. Many who suffer from this condition find it affects their days and nights, their everyday functions, and may impact their quality of life and well-being. To-date, there are no approved treatments for this condition. CLE-400 is a topical formulation containing a potent α2-adrenergic agonist molecule that is both a non-opioid and a non-steroid.   For more information on CLE-400: https://lnkd.in/dqsbbiEJ #nervepain #notalgiaparesthetica #clexio #clinicaltrials