Determining drug-to-antibody ratios (DAR) is critical for ADC development. Streamline your DAR analyses with a streamlined mass spectrometry and data analysis workflow solution from SCIEX: https://bit.ly/4aWarx4 #DanaherLifeSciences #ZenoTOF #BiologicsExplorer massspec #dataanalysis
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Struggling with #chiral separations and managing data? Discover a smarter approach with Chrom Best Method! In this application note, Prof. Rafael Cela and Dr. Leticia Pérez-Mayán from CIM Mestrelab showcase the effectiveness of Chrom Best Method in evaluating LC separation of diniconazol. Learn how #DataAnalysis automation informs decisions and streamlines the method screening process. 📖 Download the application note here: https://lnkd.in/d5X3ebGy #preparativechromatography #LCMS #GCMS #dataautomation #drugdiscovery
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President of SciY (Integrated Data Solutions division at Bruker BioSpin), CEO at MESTRELAB RESEARCH SL, Chairman IMSPEX DIAGNOSTICS LTD, General Partner Bio&Tech Smart Capital and Board Member at Bioga Galicia
Automating the workflows of #chiral separations, and, in fact, the whole #purification workflow with a simple to use set of #Mgears tools, from the #Mnova platform by Mestrelab Research S.L. is a utility that can significantly help to accelerate #drugdiscovery and #drugdevelopment in the #biopharma industry If you are working on #chromatography , this tools can save you a lot of time and speed up your research Do get in touch with Mestrelab Research S.L. to check it out !
Struggling with #chiral separations and managing data? Discover a smarter approach with Chrom Best Method! In this application note, Prof. Rafael Cela and Dr. Leticia Pérez-Mayán from CIM Mestrelab showcase the effectiveness of Chrom Best Method in evaluating LC separation of diniconazol. Learn how #DataAnalysis automation informs decisions and streamlines the method screening process. 📖 Download the application note here: https://lnkd.in/d5X3ebGy #preparativechromatography #LCMS #GCMS #dataautomation #drugdiscovery
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Learn about key challenges in quantitative large mol analysis due to non-specific binding and how to overcome them using QuanRecovery #samplevials and plates in your workflow. https://bit.ly/3xxBwrS
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The SampleStream Platform is an ideal partner for affinity capture/immunoprecipitation. In this work, Seckler et al. use a bead-based IP to capture proteoforms of ApoAI and ApoCIII from participants in a major study cohort. The samples were then processed via SampleStream-Mass Spectrometry and compared to LC-MS analysis of the same samples. While this early version of SampleStream suffered a slight sensitivity deficit to the LC-MS approach, it provided 7x the throughput and reduced CVs by over 50%. The simplicity and speed of the platform eliminates many of the failure modes associated with liquid chromatography and the improved speed reduces the impact of instrument drift. How can we help with your affinity capture workflow? https://lnkd.in/gmm-vPJc
New Interface for Faster Proteoform Analysis: Immunoprecipitation Coupled with SampleStream-Mass Spectrometry
pubs.acs.org
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CEO at Integrated Protein Technologies, Inc. Research Associate Professor at Northwestern University
The SampleStream platform is ideal of interfacing affinity capture workflows to mass spectrometry and this work by Seckler et al. demonstrates a few of the reasons why: 1.) Concentration - The SampleStream platform is a molecular trap, so the entire IP elution volume can be injected and concentrated into a fixed elution volume. The result of this concentration is improved sensitivity for challenging targets. 2.) High Throughput - Affinity purified samples are relatively simple and in most cases current HRAM MS system are capable of resolving all of the components without the need for LC. The SampleStream platform gets samples to the MS fast (1-3 min per sample depending on target MW) so you can get data back to your stakeholders fast. 3.) Buffer Exchange - Affinity selection workflows sometimes require the use of elution buffers that are not mass spec compatible. The SampleStream platform rapidly exchanges many of these components so no further processing is required.
The SampleStream Platform is an ideal partner for affinity capture/immunoprecipitation. In this work, Seckler et al. use a bead-based IP to capture proteoforms of ApoAI and ApoCIII from participants in a major study cohort. The samples were then processed via SampleStream-Mass Spectrometry and compared to LC-MS analysis of the same samples. While this early version of SampleStream suffered a slight sensitivity deficit to the LC-MS approach, it provided 7x the throughput and reduced CVs by over 50%. The simplicity and speed of the platform eliminates many of the failure modes associated with liquid chromatography and the improved speed reduces the impact of instrument drift. How can we help with your affinity capture workflow? https://lnkd.in/gmm-vPJc
New Interface for Faster Proteoform Analysis: Immunoprecipitation Coupled with SampleStream-Mass Spectrometry
pubs.acs.org
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⏰ Tomorrow is the day! Be part of our webinar and delve into the world of liquid chromatography advancements. Learn how to overcome non-specific interactions, enhance data quality for metal-sensitive molecules, and master advanced data processing techniques for LC-MS datasets. Register now! https://zurl.co/Yw3g #Shimadzu #WebinarTomorrow #LiquidChromatography #AnalyticalMethods #DataProcessing
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"🔬✨ Elevate your lab game with our H8-HBA1C Analyzer! 🚀 Precision meets efficiency as our carousel magic takes multitasking to the next level. Fast-track through samples, enjoy user bliss, and dive into spot-on results! 🌟 Your lab's data masterpiece starts here!" https://shorturl.at/belr5 #clinicalautomationservices #HBA1CAnalyzer #H8Analyzer #medicaldiagnostics #medicaldiagnosis #medigaldiagnosticequipment #diagnostic #diagnostics #diagnosis #diagnostictools #diagnose #diagnosticequipment #biochemistry
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Learn about running 10 microliters of sample with m-VROC II https://hubs.ly/Q02tK2C-0 #smallsample #viscosity #data #science
Accurately Measuring Viscosity with only 10 μL on m-VROC II
rheosense.com
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🚨 New data alert! 🚨 Have you checked out XiFin's Lab Volume Index recently? It's been updated with data through April! Take a look: https://hubs.li/Q02xCF1b0 #lvi #data #insights
XiFin® Lab Volume Index | XiFin, Inc.
xifin.com
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"🔬✨ Elevate your lab game with our H8-HBA1C Analyzer! 🚀 Precision meets efficiency as our carousel magic takes multitasking to the next level. Fast-track through samples, enjoy user bliss, and dive into spot-on results! 🌟 Your lab's data masterpiece starts here! " https://shorturl.at/belr5 #clinicalautomationservices #HBA1CAnalyzer #H8Analyzer #medicaldiagnostics #medicaldiagnosis #medigaldiagnosticequipment #diagnostic #diagnostics #diagnosis #diagnostictools #diagnose #diagnosticequipment #biochemistry
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