Danish Cancer Institute’s Post

Exciting breakthrough in cancer research! A new roadmap uncovers how aggressive cancer cells migrate from the prostate to other organs. The study, in collaboration with Weill Cornell Medicine, used a novel mouse model (EvoCaP) and analysis pipeline (EvoTraceR) to trace individual cancer cell movements with genetic barcodes. Learn more: [Link to article] #CancerResearch #MedicalDiscovery

On #GlioblastomaAwarenessDay, we honour those affected by this devastating #BrainCancer. “We are working to develop new drugs including those that target especially challenging and novel targets – drugs which we hope will improve the survival rates of cancers that remain hard to treat.” ICR’s Chief Executive Professor Kristian Helin. With your support, we can continue our vital research to transform the lives of people with this disease. Find out more about our research into brain cancer ⬇ #TheInstitueofCancerResearch #CancerResearch #DrugDiscovery

Why senescence starts before birth Last week the SenesceX project meeting at the Spanish National Cancer Research Center Spanish National Cancer Research Centre (CNIO) brought together the senescence research community in Madrid and leaders in the field such as Masashi Narita, from Cancer Research UK (CRUK), and Manuel Collado Rodríguez (Fundación Pública Galega Instituto de Investigación Sanitario de Santiago de Compostela (FIDIS), and president of the Spanish Society of Cellular Senescence. SenesceX is a consortium funded by Comunidad de Madrid that “seeks to clarify the role of senescence in processes as diverse as embryonic development, aging and cancer, and to provide new therapeutic strategies to combat diseases resulting from inefficient senescence,” says Eva Gonzalez Suarez, coordinator of SenesceX and head of the Transformation and Metastasis Group at CNIO. In relation to cancer, in particular, the evidence points to the fact that senescent cells promote tumor growth and aggressiveness. In addition, there are anti-tumor treatments (chemotherapy, radiation, CDK4/6 inhibitors) that induce senescence, and these senescent cells promote recurrences and metastasis. Also participating in SenesceX are Nabil Djouder, head of CNIO Growth Factors, Nutrients and Cancer Group at the CNIO; Ignacio Palmero, from the Instituto de Investigaciones Biomédicas de Madrid - CSIC; Ana O'Loghen, from the Centro de Investigaciones Biológicas Margarita Salas (CSIC); and Marta Magariños Sánchez from the Universidad Autónoma de Madrid (UAM). https://lnkd.in/drHBe4-d

FRANCOISE BETTENCOURT MEYERS L'OREAL HEIRESS c/o ODEON RESTAURANT TRIBECA NY WHAT'S ON THE TABLE UPSTAIRS.? I HOPE NY HAMPTON BEACH HOUSE.! LATE JOSE' CHEF & LOUIE BERKSHIRE HATHAWAY WARREN BUFFET Chairperson MAYE MUSK Supermodel.. E. MUSK.. Mother BILL & MELINDA GATES FOUNDATION GATESFOUNDATION.org Tenri.org TENRI CULTURAL INSTITUTE GALLERY SPRING THEME Cryptocurrency REYGITONIUM-G https://lnkd.in/e55sRd8b https://lnkd.in/eB98Jnv9 WonderMind.com WHAT'S ON THE TABLE*Crypto-REYGITONIUM-G MR. MS. TEEFEY & SELENA GOMEZ-RARE-SUPERSTAR TO WHOM IT MAY CONCERN I ABSOLUTELY SEE NOTHING WRONG WITH CRYPTO-REYGITONIUM-G I CAN UNDERSTAND WHY THE INFANT DEMOCRATIC-CAPITALISTIC MINDS BLAME USA GOVERNMENT. THEN IS ANY GOVERNMENT TO BE BLAMED FOR HOMELESS PROBLEMS PLAGUING THE WORLD.? NO. GOD KNOWS HEADACHES US GOVERNMENT HAVE WITH THE FOREIGN AFFAIRS. THE NEW WORLD TRUE SHOCK TO WITNESS. PEOPLE WORKING TOGETHER FOR A COMMON GOAL. IN THE PURSUIT OF HAPPINESS. DOESN'T THAT ALSO INCLUDE THE HOMELESS. THE HOMELESS ARE OUT THERE. ARE YOU.? HOMELESS.. OPPORTUNITY MISUNDERSTOOD. The modern economic system is a market economy, which is a capitalist economy where people, not the government--NOT THE GOVERNMENT--own most businesses. In a capitalist economy, prices allocate capital and labor between competing uses, and capital assets can be privately owned and controlled. GOOGLE https://lnkd.in/eB98Jnv9 EXAMPLE IF YOU NEED TO RAISE MONEY FOR ANY REASON OR LETS SAY THE "HOMELESS" PROBLEM WHICH IS BELIEVED TO BE TIME & MONEY CONSUMING BUT IN ONE DIRECTION TOWARD THE HOMELESS. HOWEVER CRYPTOCURRENCY CAN POSSIBLE ALLOWS AN EXPENDITURE OF CRYPTOCURRENCY TO BENEFIT ALL WHO USES THE CRYPTO & REGARDLESS OF HOW IT'S CONSUMED. THEREFORE IF A CRYPTO-CURRENCY REYGITONIUM-G EXISTED IT'S MORE HIGHLY LIKELY THE HOMELESS PROBLEM CAN BE VANQUISHED BECAUSE CURRENCY FINANCES WILL ALWAYS BE AVAILABLE TO BE TAPPED INTO FOR HOMELESS RESOLUTIONS. REYGITONIUM-G: EACH COUNTRY GOVERNMENT INITIAL $1-DOLLAR INVESTMENT PORTFOLIO OF 8-BILLION EARTH CITIZENS. THEREAFTER GLOBALLY ANYBODY CAN INVEST IN THE CRYPTO-REYGITONIUM-G. FAMILY SECURITY. OR CONTINUE HIDING THE HOMELESS WHEN A POLITICAL LEADER VISITS AMERICA. CLOSING COMMENT: THE DAMNEDEST CRAZIEST FUNNIEST EMBARRASSING ABOUT THE HOMELESS CHAOS IS ANY EXCUSE AS TO WHY HOMELESS EXIST. HENCEFORTH CONSIDER USA TRILLIONS IN DEBT & 6,120 HOSPITALS SCATTERED AROUND THE USA & MANY COUNTRIES ASKING FOR FOREIGN AID IN THE TRILLIONS & YOU TALKING EXCUSES. MEANWHILE WE WANT TO SETTLE HUMANITY ON OTHER PLANETS. THANK YOU FOR READING.

𝐈𝐍𝐓𝐄𝐑𝐕𝐈𝐄𝐖|  🧬 💾 𝐄𝐯𝐚 𝐁𝐮𝐝𝐢𝐧𝐬𝐤𝐚́ from the 𝐑𝐄𝐂𝐄𝐓𝐎𝐗 center is expert bioinformatician and biostatistician. 🩺 In her field, she focuses on the analysis of molecular and imaging data in oncology, specifically she is interested in colorectal cancer. 💬 In the interview, she explains what exactly her cancer research entails, where it is headed, and why connecting it wit the microbiome is essential. 👉 https://lnkd.in/egxqPM5a

The Positive Impact of Cancer Research on Health Cancer, often seen as a devastating disease, has surprisingly contributed to remarkable advancements in science and medicine. The study of cancer has provided deep insights into cell biology, uncovering mechanisms like cell signaling and apoptosis that impact our understanding of many diseases beyond cancer. One major breakthrough from cancer research is precision medicine, which tailors treatments based on a patient’s unique genetics. Drugs initially developed for cancer, like Herceptin, are now being used to treat other diseases such as autoimmune disorders. Cancer research has also advanced regenerative medicine by studying how cancer cells avoid death, helping scientists explore treatments for heart disease and tissue regeneration. Additionally, innovative cancer detection tools like liquid biopsies are now being applied in early disease detection and prenatal care. Cancer research has undeniably opened doors to medical progress, benefitting humanity in unexpected ways. For more biotech insights, check out my blog: BioVision by Mirthulaa at https://lnkd.in/guPJ-Wvd. — Mithulaa

Senescence Network was an incredible experience, especially the insightful presentation by Dr Daniel Muñoz-Espín from the Cancer Research UK Cambridge Centre. His session on "Senescent Ecosystems in Lung Cancer: Therapeutic Opportunities" was a deep dive into the innovative approaches towards cancer therapy using senescence.  Dr Muñoz-Espín's research focuses on the pivotal role of senescent cells within the tumour microenvironment and their impact on lung cancer progression. He highlighted groundbreaking methods to target these cells, aiming to disrupt their support of tumour growth. His work with the p16-3MR mouse model demonstrates significant findings where senolytic drugs selectively clear senescent cells, decreasing tumour growth and potentially increasing patient survival rates.  Another fascinating aspect of his talk was the use of advanced genomic and proteomic profiling to identify senescence-associated secretory phenotype (SASP) factors that promote tumorigenic processes. This approach could pave the way for therapies that treat and prevent cancer. I would like to express My heartfelt gratitude to the organizers for a well-curated event that provided us with such enriching insights. I am also deeply appreciative of Dr. Muñoz-Espín for his compelling presentation that significantly expanded our understanding of the potential of senolytic therapies in oncology.  Looking forward to more breakthroughs and the next meeting, which will continue this fascinating discussion on cancer and cellular senescence! #CancerResearch #Senescence #Oncology #MedicalInnovation #ICSA

Cancer isn't a single, straightforward disease. It's more akin to a collection of malevolent molecular adaptations used by cells to grow out of control. To effectively combat cancer, we need to understand these adaptations at the molecular level. MicroRNAs are tiny RNA molecules that act like orchestra conductors inside our cells. They have the remarkable ability to silence hundreds of genes in a coordinated manner, regulating crucial processes such as cell division and migration. When these processes go awry, it can lead to the aggressive behaviours exhibited by cancer cells. Recent discoveries have shed light on mutations in the proteins responsible for safeguarding the integrity of microRNAs in cancer patients. These mutations cause microRNAs loaded into these defective proteins to degrade much faster, potentially contributing to tumor formation. With the support of a grant from the NEYE Fonden, our research aims to delve into the intricate molecular mechanisms underlying microRNA regulation in tumours. This project will be lead by Dr. Nina Nelson, a Walter Benjamin Postdoctoral fellowship awarded by Deutsche Forschungsgemeinschaft (DFG) - German Research Foundation, who recently joined out team. Together, we will investigate what factors cause microRNAs to degrade over time and explore the mechanisms cells employ to repair damaged microRNAs. By gaining a deeper understanding of these molecular processes, we hope to pave the way for the development of therapies that prevent the decay of microRNAs, even when loaded into defective proteins. Ultimately, our goal is to harness these insights to develop more effective therapeutic strategies. #MicroRNAs #CancerResearch #NEYEFoundation #DFG

New Cancer Article! Prostate cancer is a devastating disease that affects millions of men worldwide. Despite advancements in treatment options, aggressive forms of the disease, such as metastatic castrate-resistant prostate cancer (mCRPC), remain a major challenge. However, a recent study conducted by researchers at the University of Chicago Medicine Comprehensive Cancer Centre has established a promising “proof-of-concept” for a new treatment approach that could revolutionize the field. The study, published in Clinical Cancer Research, demonstrated the remarkable effectiveness of this novel treatment in a mouse model of advanced prostate cancer. The researchers achieved complete tumour control and long-lasting survival without any side effects. These ground-breaking findings have paved the way for further investigation in human clinical trials……. Read the rest of the article: https://lnkd.in/ewsTuvgd Written by: Sara Maria Majernikova Check it out and share! #article #website #research #cancer #prostatecancer #prostate #cancertreatment #science #clinicaltrial #cancerresearch #scientianews #studentsuk Prostate Cancer UK Cancer Research UK (CRUK) Cancer Research Institute (CRI) NCI Center for Cancer Research Cancer Research UK Science and Innovation Prostate Cancer Research Prostate Cancer Foundation

✨ Want to be inspired by our next generation of cancer researchers? ✨ Thanks to The Charles Bulley Foundation, Rick Horvat CFP, and Tour de Cure Australia, I had the pleasure of calling these four exceptional young female researchers to award them Tour de Cure’s 2024 ‘Samantha Hollier-James PhD Research Scholarship,’ which contributes $10,000 to support their ambitious cancer research. Selected from a highly competitive pool of Australian PhD cancer research applications by Tour de Cure Australia's Grants Committee, these researchers represent the future of innovation and hope in cancer treatment and prevention. 🌟 Massive congratulations to our 2024 winners! 🌟 It was a privilege to personally call each of you, share the exciting news, and hear about the incredible outcomes you aspire to achieve in your research. Ms. Tess Symington (University of Newcastle) – Her research aims to provide an additional treatment option for endometrial cancer sufferers, through repurposing RAS antagonists, and, ultimately, a method for early detection! Miss Georgia Lewis (University of Wollongong) – Her research aims to build on recent insights into inceptors and push the limits of localised radiotherapy treatments to reduce lifelong side effects on healthy tissues. Mrs. Shay Arabi (University of Melbourne) – Her research aims to develop a molecular pathway, so patients don’t need to gain weight, while also building effective new targeted treatments for melanoma. Ms. Zahra Esmaeili (University of South Australia) – Her research aims to target cancer-associated fibroblasts to prevent the progression of breast cancer. 🌟 🌟 🌟 Your passion and dedication inspire us all, and I can’t wait to see the impact you’ll make. #CancerResearch #TourdeCure #CureCancer #ChangingLives #NextGenResearchers #InnovationInScience