Darling Ingredients’ Post

+++++++++ #Avian #influenza H5N1 virus is going to cause more outbreaks: Why?++   We failed with #coronaviruses, but we never tried to analyze the reasons behind this failure. A few reasons for this failure include a lack of understanding of #virology itself, which has led to the use of subpar tests, therapies, and vaccines to control the virus. Many companies lack the necessary experience in developing diagnostic tests, primarily because they are instrument manufacturers. To develop effective tests, one must dedicate months or years to understanding the structures of the virus, rather than relying solely on software. We are repeating the same mistakes with the avian influenza H5N1 virus, which will result in new outbreaks in the future. These outbreaks will spread the pathogen to numerous other species, posing a challenge for control. Additionally, this virus will combine with other avian influenza viruses, generating new strains that will render current measures ineffective. It is time to act honestly; otherwise, this virus is going to teach us very bad lessons. We need to discuss these reasons for our failure and act to correct them! #Medicine https://lnkd.in/eEy52ZjG

Why do we need to understand #ONEHEALTH approaches and #CommunityEngagement? When it comes to protecting health security, it is critical to adopt an expansive view of health, one that includes animals and the environment, and also considers the role played by the community in ensuring disease surveillance across all three sectors. This One Health view is defined as “an integrated, unifying approach that aims to substantially balance and optimize the health of people, animals, and ecosystems.” Broadly speaking, the concept views the health of humans, animals, and the ecosystem as connected and mutually dependent. In the case of the below article, we see yet another example of the animal-to-human interface in infectious diseases and how health crosses sectors. According to World Health Organization, over 30 new human pathogens have been detected in the last three decades, 75% of which have originated in animals. In order for One Health approaches in addressing outbreaks to be effective, #CommunityEngagement is essential. Community engagement in animal disease surveillance and response is critical for several reasons. Zoonotic diseases are those that can infect humans and animals. Because infections can spread from animals to humans (and vice versa), community surveillance regarding animal health can serve to alert healthcare providers to the emergence of dangerous diseases in the animal world that threaten to spill over into humans. Examples include Middle East Respiratory Syndrome (MERS), which is transmitted from camels to people, and Rift Valley Fever, which can infect humans living in close proximity to affected cows, goats, sheep and camels. Another great example in Rwanda is outlined by Drs. Henly, Igihozo, and Wotton (Nature, 2021) here: https://lnkd.in/erbT78BD Strengthening community engagement in animal health and disease surveillance also builds confidence in health interventions and innovations. In pastoralist or agricultural communities, when public officials and health workers offer vaccines and other services to protect the health of livestock and domestic animals, the trust and goodwill built among families and providers can help open a dialogue with community members about providing children and adults with health services, as well. Gwakisa, et al. (One Health Outlook, 2023) also speak of community engagement, systems analysis, & transdisciplinarity as "pillars for One Health ecosystem approach." To see more information on One Health approaches by the CORE Group #CGPP project, please see resources here: https://lnkd.in/e3UAeBzB https://lnkd.in/eFWaMGEU

Today marks 139 years since Louis Pasteur administered the first rabies vaccine, a virus transmitted between animals and humans. For this reason, we celebrate #WorldZoonosesDay 🌍, dedicated to raising awareness about zoonotic diseases such as salmonella and COVID-19. These diseases can be transmitted directly through contact between animals and humans or through food, air, water, or vectors. The excessive use of antibiotics increases the risk of the emergence of drug-resistant zoonotic pathogen strains. At #HIPRA, we are committed to One Health and work to offer innovative solutions in human and animal health. This places us in a unique position to prevent zoonotic diseases. Currently, our R&D🔬 teams are researching more than 300 pathogens, some of which are included in the WHO's risk list for future pandemics. #AnimalHealth #HumanHealth #OneHealth

I remain highly concerned about the US H5N1 avial influenza outbreak and not enough being done to investigate and control it. CDC have now confirmed H5N1 in some foxes and possums in the infected regions. This plus the deaths of infected cats and Texas waste water studies suggests that H5N1 might be spreading in wild or domestic animals entering residential areas? We know cats are highly susceptible so imagine what happens if this starts spreading in the US cat population. At least there should be a strong signal of this happening if cats start dying everywhere from respiratory symptoms - I wouldn't want to be a vet having to look after such animals right now in absence of a vaccine.   So the focus may be incorrectly too much on the infected dairy cattle, at a time when H5N1 might already be in another intermediate species from which it could much more easily cross to humans, for example most people are in much closer contact to cats than they are to cattle!   We just need to remember what happened in the ferret farms with COVID where it freely transmitted from the humans to ferrets and back to humans acquiring mutations along the way.   US authorities seem to be doing too little to investigate and rapidly control this outbreak – actions in the first few weeks of an outbreak are by far and away the most crucial as we saw with the failure to react to and control SARS-CoV-2 early enough.

The CDC is actively responding to a multistate outbreak of avian influenza A(H5N1) virus affecting dairy cows and other animals in the United States. They are using a One Health approach collaborating with the USDA, FDA, state health officials, and local partners. As of May 30, 2024, Michigan reported a third human case of A(H5) virus infection linked to the ongoing outbreak in U.S. dairy cows. Like the previous cases, this individual is a dairy farm worker with direct exposure to sick cows, suggesting cow-to-person transmission. Despite this recent case, the CDC’s risk assessment for A(H5N1) bird flu in the general public remains unchanged. All three sporadic cases had contact with infected cows. USDA confirms 68 dairy cow herds in nine states with A(H5N1) infections. Continued flu surveillance, limiting animal-human interactions, and urgent efforts by USDA and partners are essential to prevent further spread. 🦠🐄👨 For more detailed information, you can refer to the attached CDC’s official report. Your dedication to public health is commendable! 🙌 #OneHealth #GlobalHealthSecurity #FHI360GSH

The potential #OneHealth and #FoodSecurity impact of the intrepid #H5N1 virus bears close watching by authorities and industry. There are potential implications for wild, farmed, and companion animal health, the risk of animal-human and human-human transmission, and implications for animal product #foodsafety and #foodsecurity. So it is apt that the FAO, World Organisation for Animal Health, and World Health Organization triad are monitoring the situation closely. In the U.S., where infections had been noted in cows, the FDA updated on 25 Apr that 1 in 5 PCR-tested retail milk samples showed viral fragments, but added on 26 Apr that "preliminary results of egg inoculation tests on quantitative polymerase chain reaction (qPCR)-positive retail milk samples show that #pasteurization is effective in inactivating HPAI. This additional testing did not detect any live, infectious virus. These results reaffirm our assessment that the commercial milk supply is safe." [Reference: https://lnkd.in/gH7X4Ni7 ] The FDA has advised "Precautions for Raw Milk" as follows: "The FDA has a long-standing recommendation to consumers not to consume raw milk (milk that has not been pasteurized). Because of the limited information available about the possible transmission of H5N1 virus via raw milk, the FDA continues to recommend that industry does not manufacture or sell raw milk or raw milk products, including raw milk cheese, made with milk from cows showing symptoms of illness, including those infected with avian influenza viruses or exposed to those infected with avian influenza viruses. Importantly, the FDA has also recommended producers take precautions when discarding milk from affected cows so that the discarded milk does not become a source of further spread. Producers should consult with their state regulatory authorities for specific recommendations or requirements; however, such precautions should include heat treatment, pasteurization or its equivalent, of discarded milk prior to dumping in lagoons or application of waste solids and ensuring biosecurity around lagoons (e.g., ensuring that animals and birds do not have access to lagoons). Any raw milk or raw milk products from exposed cattle that are fed to calves (or to other animals, such as farm cats) should be heat treated or pasteurized." #zoonosis #publichealth

🔍 Explore the critical dynamics between avian infectious bronchitis (IBV) and pathogenic Escherichia coli (APEC) in our latest article! Discover how certain strains of IBV may predispose birds to severe secondary infections by APEC, leading to significant health issues like aerosacculitis. 🧬 Dive into our comprehensive analysis to understand: How IBV damages the respiratory system, increasing susceptibility to APEC infections. The impact of various IBV strains on the severity of secondary infections. Strategic prevention measures to mitigate these risks in poultry production. 🚀 Plus, uncover the economic implications for the poultry industry and why integrated disease management and early warning systems are crucial for maintaining both bird health and farm profitability. 👉 Read the full article for a deeper insight and practical guidance on protecting your poultry investments. https://lnkd.in/efgyKspJ #PoultryHealth #VeterinaryScience #AnimalDiseaseManagement #PoultryFarming

The Animal and Plant Health Agency (APHA) in the UK reported in January that the number of cases of congenital abnormalities in lambs caused by Schmallenberg virus (SBV) had increased across the UK since the end of 2023. A total of 63 cases were confirmed by APHA between 1 December 2023 and 16 January 2024. Also in the Netherlands, the Veekijker has received several reports of lambs with congenital abnormalities since the beginning of 2024. Pathological examination has confirmed that the deformities in the lambs reported are the result of SBV infection. Read the full article in the latest Small Ruminants Highlights report. Other topics in this issue: - Submitting foetus and afterbirth is important for abortion diagnostics - Epididymitis in the abattoir - Outbreak of E. coli on a dairy goat farm - Ovine herpes virus type 2 - Blindness in sheep - Paratuberculosis in dairy goats https://lnkd.in/e22Ah5G2 #AnimalHealth #SmallRuminants #Sheep #Goats #SchmallenbergVirus #Ecoli #OvineHerpesVirus #Paratuberculosis

#HPAI in #dairy cows. As many questions abound, FAO, World Health Organization and World Organisation for Animal Health conduct a preliminary risk assessment focusses on #Avianinfluenza A(H5N1) viruses and assesses the public health risk as well as the risk of the virus spread among animals. FAO and World Health Organization strongly advise the consumption of only #pasteurized milk and to avoid consuming raw milk We will continue to monitor and re-assess the risks as the situation evolves and when more information becomes available. A #OneHealth approach with rapid sharing of information and sequence data from both the human and animal health sectors is strongly recommended and is critical for rapid risk assessment. https://lnkd.in/d_EUWH7E #OneHealth #OFFLU #foodsafety