Don Wellings’ Post

Join us on August 22 at 8:00 PDT / 11:00 EDT / 16:00 BST / 17:00 CEST for an in-depth webinar titled "Optimizing bioprocess purification: effective nucleic acid removal in high salt environments". We warmly invite our valued customers to participate in this informative session. Our esteemed experts, Dr. Eleonora Turco, Director of R&D Enzymes, and Dr. Joanna Niska-Blakie, Global Product Manager, will cover the following topics: - Challenges in nucleic acid removal: Understand why traditional methods fall short. - Meet Saltonase: Discover this advanced salt-active endonuclease, known for its stability and effectiveness. - Implementation strategies: Learn how to integrate Saltonase into your workflows. - Case studies: See real-world applications and success stories. You can sign up here - https://lnkd.in/e8vU269e

We are excited to reveal our collaboration with Noël Research Group! 🚀 A new bench-stable reagent - 4-trifluoromethyl-phenyl sulfonyl hydrazone is now commercially available at Enaminestore! 🛒 https://lnkd.in/gdYMQ3Fm This reagent can be used successfully for the mild and metal-free protocol of preparing a wide array of alkyl-alkyl cross-coupled products. For more information about this simple and versatile method please see the publications: https://lnkd.in/eSXfCEEd https://lnkd.in/eQ2RE-K9 Whether you’re focused on optimizing synthetic efficiency or exploring new reactions, ethyl glyoxylate-derived 4-trifluoromethylphenyl sulfonyl hydrazones offers a practical, reliable pathway for your research. Available in stock now! #Collaboration #SyntheticChemistry #CommercialReagent #ResearchAndDevelopment #ScientificInnovation #radicalchemistry #OrganicChemistry

We're going to measure the activity of extracellular cellulase from our microbial culture. First, we'll grow the microbes and collect the enzyme-rich supernatant. We'll then prepare a cellulose-based substrate and mix it with the enzyme. After allowing time for the enzyme to work, we'll use a DNS assay to detect the sugars produced. By measuring the color change in a spectrophotometer, we can quantify the enzyme activity and understand how effective our cellulase is... #CellulaseAssay #EnzymeActivity #BiotechResearch #MicrobialEnzymes #Biochemistry

New Year, New Paper🚀 Today, we report a biocatalytic platform that employs a C–C bond disconnection strategy to broaden Nature's lactone synthesis approaches, which rely solely on a C–O bond disconnection. After 20+ rounds of #directedevolution, we obtained engineered enzymes that catalyze carbene insertions to make 5-, 6-, 7-, 8-membered, fused-, spiro-, and bridged-lactones, even unprotected lactam and cyclic ketone from simple starting materials with up to 5600 total turnovers and >99% ee. Great collaborations w Daniel Wackelin, Dr. Kai Chen, Kathleen Sicinski, PhD, Yutao Zhao, and Anuvab Das. Special thanks to my supervisor, Frances Arnold for everything!! #directedevolution #proteinengineering #enzymes #biocatalysis

JBC cover art shows carbon monoxide dehydrogenase (CODH) and acetyl-CoA synthase (ACS), two key enzymes found in the Wood-Ljungdahl pathway of acetogenesis. ➡️Learn more and explore the Sept. 2024 issue of JBC: https://lnkd.in/eSbUGb3Q.

Do not miss this new technical article in Feedinfo providing an overview on important feed enzyme parameters, their relevance for stability and activity level, and characteristics of Natupulse® TS, our new ß-mannanase enzyme. For more information on Natupulse® TS you can also visit: https://lnkd.in/gYYQVGBE #Enzymes #FeedEnzymes #AnimalFeed #AnimalNutrition #NatupulseTS

Which parameters are important for enzyme stability? If you want to learn more about this topic in general & our new mannanase enzyme Natupulse TS specifically, read our new article 😊!

JBC cover art shows carbon monoxide dehydrogenase (CODH) and acetyl-CoA synthase (ACS), two key enzymes found in the Wood-Ljungdahl pathway of acetogenesis. ➡️Learn more and explore the Sept. 2024 issue of JBC: https://lnkd.in/eSbUGb3Q.

If you understood the power of what these molecules do in your body you would never want to be without ASEA Redox. People often describe the experience as a "miracle"! But it's just science. ASEA Redox has trillions of bioactive Redox Signaling Molecules in each bottle. Certified and guaranteed. Your cells make these, they are critical to life, but most of us no longer make enough for vibrant, problem-free health. Creating a supplement was a medical dream, but considered impossible. ASEA achieved it. First, ASEA uses reverse osmosis and deionization to make one of the purest waters on the planet. The Megatron system constantly runs 200 gallons of water per minute in a loop under UV light removing all bacteria and impurities, officially classifying it as "ultra-pure". They mix that with salt and take it through the revolutionary process that creates bioactive redox signaling molecules. A process that took over 17 years to perfect, has 7 patents, and over 1,000 trade secrets. This is how the ASEA Redox Supplement is created. Each batch takes several days. https://lnkd.in/eYtzG_Y #itsnotmiracleitsscience #asearedox by #ASEAGlobal #redoxsignalingmolecules #changeyourlife #oneofakind #patentedtechnology #LiveYoungerLonger #WePowerPotential

Upkara is now Ambient Biosciences! We are shifting the paradigm of biomolecule stabilization. If you are interested in learning how our technology can reduce your costs, simplify assay workflows and reduce your carbon footprint I would love to talk. #breakthecoldchain