DTU Biosustain’s Post

What an honor to be published (again) in Nature Magazine, one of the most prestigious scientific journals in the world! 📰 Publishing an article in Nature is remarkable, publishing TWO articles in Nature is truly exceptional. After a first publication in 2020 on enzymatic depolymerization of PET, this new article reinforces Carbios’ scientific leadership in enzymatic biotechnologies by presenting enzyme-embedded PLA that is 100% compostable at ambient temperature. Developing an efficient enzyme that can withstand the 170°C needed to introduce it into PLA is an outstanding scientific feat! 🔬👩🔬👨🔬 This achievement would not have been possible without the hard work, passion, and dedication of our researchers, engineers, and partners. A special mention to our longstanding collaborator who co-authored the article, TBI - Toulouse Biotechnology Institute, Bio & Chemical Engineering, (joint research unit associating INSA Toulouse, CNRS - Centre national de la recherche scientifique and INRAE). A huge thank you to all the teams who contributed to this exceptional success. Together, we continue to push the boundaries of science for a greener future. #Biotech #innovation #science #biodegradation #RD #enzymes

Don’t miss out: Professor Pablo Ivan Nikel sheds light on the future of cell factory engineering in new Nature interview 🔬🌿   In an exclusive interview with Nature, Pablo Ivan Nikel, a leading researcher at The Novo Nordisk Foundation Center for Biosustainability (DTU Biosustain), shares together with other experts new insights on advancing cell factory construction and pioneering new-to-Nature chemistry.   🔍🌟 Exclusive Insights:   The interview unveils Pablo's team´s innovative strategies for engineering bacteria to synthesize compounds that are traditionally produced through chemical processes. His work promises a sustainable alternative to harmful substances, such as PFAS, by leveraging the power of bioengineering to produce chemicals and materials in a more sustainable manner. "The knowledge we've accumulated over decades on how microbial cells function has never been more crucial: we urgently need replacements for chemicals that remain difficult to produce. Programming of biology to yield an array of chemicals is becoming more accessible, and we can push bioengineering beyond merely producing trivial compounds. Both the scale and chemical nature of compounds is critical in making a tangible difference in the bioeconomy", says Pablo I. Nikel. 🌱 Transformative Impact:   Our deepening understanding of cellular processes paves the way for programming biology to create a wide array of chemicals, challenging and changing the way industries produce compounds today. The insights from Pablo I. Nikel emphasizes that the impact of these technologies is about creating scalable, impactful solutions that drive the bioeconomy forward. Pablo's team has recently partnered with researchers in The Netherlands to further expand the scope of new-to-Nature bioproduction in bacteria by altering the redox machinery of cell factories to enable high product titers and yields.👏   🔍You can read the full article here: https://lnkd.in/g5RDAd_w   #sustainability #biotechnology #DTUBiosustain #FutureOfBioengineering #SustainableInnovation #Bioeconomy DTU - Technical University of Denmark Novo Nordisk Foundation

📣I am pleased to announce that our paper on "Green Nanobiocatalysts: Enhancing Enzyme Immobilization for Industrial and Biomedical Applications" has been published in the PeerJ { Q1, IF:3, 8} and is now accessible online.✨📝 The Review explores nanobiocatalysts (NBCs), which combine enzymes with nanomaterials to enhance enzyme durability, efficiency, and recyclability using eco-friendly synthesis methods. It examines various immobilization techniques and emphasizes the environmental benefits of green-synthesized nanomaterials from natural sources like plants and bacteria. NBCs are showcased for their diverse applications in industries such as food production, biofuels, and bioremediation, as well as their potential in advancing biomedicine, highlighting their pivotal role in sustainable enzyme technology and biomedical innovation. Here is the link to “Green Nanobiocatalysts: Enhancing Enzyme Immobilization for Industrial and Biomedical Applications” : https://lnkd.in/dvs597Px Special Thanks to Dr/ Doaa Rashwan for her efforts and Guidance.❤️ I’m happy and proud to be one of her student ❤️ #Review_article #Research #Biotechnology #enzyme_immobilization #Biosynthesis #Medical_search

𝐒𝐮𝐛𝐥𝐢𝐦𝐞 𝐚𝐝𝐯𝐚𝐧𝐜𝐞𝐝 𝐜𝐨𝐮𝐫𝐬𝐞 𝐨𝐧 𝐌𝐢𝐜𝐫𝐨𝐛𝐢𝐚𝐥 𝐏𝐡𝐲𝐬𝐢𝐨𝐥𝐨𝐠𝐲 𝐚𝐧𝐝 𝐅𝐞𝐫𝐦𝐞𝐧𝐭𝐚𝐭𝐢𝐨𝐧 𝐓𝐞𝐜𝐡𝐧𝐨𝐥𝐨𝐠𝐲 From 13 – 24 January, the Advanced Course on Microbial Physiology and Fermentation Technology was organized by BioTech Delft (Yvonne van Gameren, Jenifer Baptiste). Microbial physiologists, metabolic engineers and (bio)process engineers from the faculty staff, together with invited international experts from other universities and industry, will offer a combination of lectures. The course aims to familiarize participants with the integrated, interdisciplinary approach required in modern biotechnology. The program during this week is supported by a course board, Pascale Daran-Lapujade (TU Delft | Applied Sciences), Henk Noorman (dsm-firmenich). For a better understanding of the lectures and to stimulate active participation by those attending, this intensive two-week course combined lectures with group exercises and case studies organized by Prof.Em. Sef Heijnen, Henk Noorman and Robbert Kleerebezem. Fed batch tasks organized by Wouter van Winden (DSM-firmenich) and Djordje Bajić. A fieldtrip to the site of dsm-firmenich in Delft was also included in the program, at the site Cindy Gerhardt (Planet B.io) and Marcel Wubbolts (Vivici) gave interesting lectures. Followed by a tour in the Food Innovation Center organized by Elaheh Jamalzadeh and Joris Kloek , and a tour in the Rosalind Franklin Biotechnology Center lead by Henk Noorman and Cees Sagt. The 25 participants in the course are from all over the world and work in industry or at an university. “𝘎𝘳𝘦𝘢𝘵 𝘤𝘰𝘶𝘳𝘴𝘦! 𝘐𝘯𝘴𝘵𝘳𝘶𝘤𝘵𝘰𝘳𝘴 𝘢𝘳𝘦 𝘦𝘹𝘵𝘳𝘦𝘮𝘦𝘭𝘺 𝘩𝘦𝘭𝘱𝘧𝘶𝘭” Interested? You can find more information regarding this course on our website via this link https://lnkd.in/ePxKQTap (Frank Bruggeman, Sarah Lieder, Björn Heijstra, Katelijne Bekers, Dietrich Kohlheyer, Jan Marienhagen, Anna-Lena Heins, Nico Callewaert, Ruud Weusthuis, Chris Mehrer, H Brett Schreyer, PhD, Mark Bisschops, Bas Teusink, Irina Borodina, Ludovic Jourdin, Marieke Klijn, Martin Pabst, Jack Pronk, Lesley Robertson, Marieke Warmerdam). #microbial #fermentation #biotechnology #engineering #biotechdelft #tudelft

Getting past the hype in biochar means being serious about research methodology. We're in the process of sharing results from several biochar studies, including some detailed blog posts for further insights. Wherever possible, we design our pot and field studies to align with research standards used by institutions like Københavns Universitet - University of Copenhagen, DTU - Technical University of Denmark, and Indian Institute of Technology, Bombay. This involves using randomised plot locations, careful sampling, triangulation of measurements, and sample triplication. Occasionally, this isn't possible. That's primarily for two reasons: Semi-commercial settings: Some studies are conducted in environments where we lack full control over research design, or where strict academic practices aren’t practical. Ongoing learning: Our recent studies are of higher quality, informed by insights gained from earlier research. We regularly collaborate with the scientific community to enhance our methodologies and share best practices. We're also transparent about the reliability of our findings, and include error bars where applicable. If these are missing, it’s often because the study fell into one of the above categories—or because of an oversight. If that’s the case, please let us know! We look forward to sharing even more solid, data-driven research and results with the community soon. Stay tuned! #biochar #researchmethodology #CDR #CarbonRemoval #MASHMakes

Building an international grade research effort within biochar has been tough, but rewarding! 🌱 I was first smitten with the visceral connection you have to one plant (biochar treated) being a bit taller than the other (control), but once the error bars were added my enthusiasm was often quelled... 🫤 However, now I get to enjoy this fully as my excellent colleagues, led by Priyanka Sathe, PhD have the research design down to an art. What I am seeing no longer just connects emotionally, but also statistically. ❤️📈 #biochar #researchmethodology #gigatonne #researchexcellence

𝐒𝐮𝐛𝐥𝐢𝐦𝐞 𝐚𝐝𝐯𝐚𝐧𝐜𝐞𝐝 𝐜𝐨𝐮𝐫𝐬𝐞 𝐨𝐧 𝐌𝐢𝐜𝐫𝐨𝐛𝐢𝐚𝐥 𝐏𝐡𝐲𝐬𝐢𝐨𝐥𝐨𝐠𝐲 𝐚𝐧𝐝 𝐅𝐞𝐫𝐦𝐞𝐧𝐭𝐚𝐭𝐢𝐨𝐧 𝐓𝐞𝐜𝐡𝐧𝐨𝐥𝐨𝐠𝐲 From 13 – 24 January, the Advanced Course on Microbial Physiology and Fermentation Technology was organized by BioTech Delft (Yvonne van Gameren, Jenifer Baptiste). Microbial physiologists, metabolic engineers and (bio)process engineers from the faculty staff, together with invited international experts from other universities and industry, will offer a combination of lectures. The course aims to familiarize participants with the integrated, interdisciplinary approach required in modern biotechnology. The program during this week is supported by a course board, Pascale Daran-Lapujade (TU Delft | Applied Sciences), Henk Noorman (dsm-firmenich). For a better understanding of the lectures and to stimulate active participation by those attending, this intensive two-week course combined lectures with group exercises and case studies organized by Prof.Em. Sef Heijnen, Henk Noorman and Robbert Kleerebezem. Fed batch tasks organized by Wouter van Winden (DSM-firmenich) and Djordje Bajić. A fieldtrip to the site of dsm-firmenich in Delft was also included in the program, at the site Cindy Gerhardt (Planet B.io) and Marcel Wubbolts (Vivici) gave interesting lectures. Followed by a tour in the Food Innovation Center organized by Elaheh Jamalzadeh and Joris Kloek , and a tour in the Rosalind Franklin Biotechnology Center lead by Henk Noorman and Cees Sagt. The 25 participants in the course are from all over the world and work in industry or at an university. “𝘎𝘳𝘦𝘢𝘵 𝘤𝘰𝘶𝘳𝘴𝘦! 𝘐𝘯𝘴𝘵𝘳𝘶𝘤𝘵𝘰𝘳𝘴 𝘢𝘳𝘦 𝘦𝘹𝘵𝘳𝘦𝘮𝘦𝘭𝘺 𝘩𝘦𝘭𝘱𝘧𝘶𝘭” Interested? You can find more information regarding this course on our website via this link https://lnkd.in/eV3ChMzN (Frank Bruggeman, Sarah Lieder, Björn Heijstra, Katelijne Bekers, Dietrich Kohlheyer, Jan Marienhagen, Anna-Lena Heins, Nico Callewaert, Ruud Weusthuis, Chris Mehrer, H Brett Schreyer, PhD, Mark Bisschops, Bas Teusink, Irina Borodina, Ludovic Jourdin, Marieke Klijn, Martin Pabst, Jack Pronk, Lesley Robertson, Marieke Warmerdam). #microbial #fermentation #biotechnology #engineering #biotechdelft #tudelft

Excited😄to announce that Biolamer Project partner, Roshanak Agharafeie from Universidade Nova de Lisboa had the privilege of presenting at the 14th European Symposium on Biochemical Engineering Sciences held from October 21st to 23rd, 2024,📅 Copenhagen, Denmark. Her oral presentation titled “Deep Hybrid Modelling of a Supercritical CO2 Extraction Process” highlighted the progress🚀 of their modeling of the Sc-CO2 extraction process, which was aimed at improving a model-by-model complexity reduction of the extraction columns of varying dimensions used for the CO2 extraction process by combining the datasets obtained from real experiments. Biolamer Project Trinity College Dublin AMBER Centre AquaInSilico HEI-Lab Human Environment Interaction Lab Universidade Lusófona - Centro Universitário Lisboa University of Bologna (Alma Mater Studiorum – Università di Bologna) Universidade Nova de Lisboa @transfolab Bcn SocLine Tech #biolamerproject #eicpathfinderopen #europeanunion #eumissions #eufunded #foodwaste #plasticpollution #hybridmodelling #circularity #circulareconomy #sustainability #biopolymers #zerowaste

Last week I defended my master's thesis titled "Characterization of the *Pseudomonas benzenivorans* 1477 strain and its ability to synthesize and degrade polyhydroxyalkanoates", which is the fruit of my stay at the CIB Margarita Salas-CSIC. I am deeply grateful for all the learning and support I have received during these last months. Finally, this work received a score of 9.3, reflecting the interest in the production of bioplastics to reduce the dependence on fossil resources and optimize the circularization of plastic waste through biotechnological tools. I must also appreciate the possibility of participating in the "JAE Intro" programme of the CSIC, which has allowed me to continue my professional development in the exciting world of research. #Research #JAEIntro #CSIC #Biotechnology

Join our upcoming course "Introduction to Biomanufacturing" and get smart on #biosolutions and #bioeconomy! 🌿