Editas Medicine’s Post

At #MeetingOnTheMesa in Phoenix, Oct. 7-9, BioSpace will provide on-site coverage exploring the progress and stumbling blocks for the #CellAndGeneTherapy sector, including the #regulatory, #manufacturing and #commercialization challenges facing the industry. Here's a preview of some of the issues stakeholders will be discussing next week. https://lnkd.in/gqf7EZnK #CGMesa24 #celltherapy #genetherapy #celltherapies #genetherapies #biotech #biotechnology #regenerativemedicine

(Reposting this - I messed up the first time ...) Part one focused on extrinsic and intrinsic particles and recommendations on #celltherapy #manufacturing can create a #riskmanagement strategy. This Part 2 focuses on a particle class called inherent particles. "Inherent," explains Drew Kelner Kelner and Andreas M. Beckhaus Beckhaus, ProDeMaCon LLC Consulting, doesn't always mean something pleasant. #biotechnology https://lnkd.in/e4tNryZw

Register now for this webinar on optimizing transient transfection scale up with the ExpiCHO expression System and the Thermo Scientific™ Nalgene™ 5 L Angled-Bottom Shake Flask. #webinar #transfection #biotechnology

9 Innovative Life Sciences Companies to Watch in 2024 Read the latest article by Bohdana Sokolova, author at BiopharmaTrend 👇 #biopharmatrend #biotech #drugdiscovery #technology https://lnkd.in/dsCHnMdy

Cell Line-Specific Impact of Dexamethasone on the Bioprocessing of Chinese Hamster Ovary Cells This study explored the cell line-specific effects of dexamethasone (DEX) on three antibody-producing Chinese hamster ovary (CHO) clones derived from different parental host cell lines: CHO-K1, -S, and -DG44. The CHO-K1 and -DG44 cell lines displayed DEX-concentration-dependent growth inhibition but had improved viability in later culture stages, extending culture longevity. Conversely, the CHO-S cell line was less sensitive to DEX regarding cell growth but exhibited a drastic decrease in viability in the later stages of culture. The cell line-specific impact of DEX (i.e. the anti-apoptotic or pro-apoptotic effects) could have resulted from the presence or absence of the GRα-D isoform and relative level of GRα-C isoform in these cell lines. This study could provide insights for optimizing production media to specific cell lines within the bioprocessing field. https://lnkd.in/g-Q3pT6Z #aspenalert #biotech #bioprocess

Honored that Bohdana Sokolova in BiopharmaTrend.com named us as a top innovator to watch in 2024. Sokolova’s article notes the wave of innovation and technological advancement sweeping through the biotech and pharmaceutical industries. She explores our pioneering #proteindesign efforts, including our groundbreaking work in “generating new proteins de novo” and our “optimization suite that refines native proteins into effective therapeutics for specific targets.” Read Sokolova’s full article below 👇🏻 #GenerativeAI | #ProteinEngineering

Save time and money with early VDJ sequence characterization so you can focus your efforts on the clones that matter. Relying on the free CD3 sequences provided by many recombinant protein production companies can be very costly. Complete VDJ Hybridoma Sequencing from iRepertoire allows you to confirm clonality prior to recombinant expression, select the best clones, and archive critical sequence information. Learn more: https://hubs.li/Q02drhGC0 #antibody #biotech #sequencing #NGS #monoclonal

Explore the power of Livecyte's automated fluorescence quantification! 📊 From analysing single cells to full 96-well plates, Livecyte enables you to investigate the cytotoxicity of multiple drug treatments simultaneously throughout the course of your experiment. Efficient, comprehensive, and insightful—watch the video to see it in action! 🎥 #Cytotoxicity #Livecyte #Imaging

🤔Can you imagine a world in which we could selectively erase disease-causing proteins from our bodies, leaving healthy cells unaffected? 𝐓𝐚𝐫𝐠𝐞𝐭𝐞𝐝 𝐏𝐫𝐨𝐭𝐞𝐢𝐧 𝐃𝐞𝐠𝐫𝐚𝐝𝐚𝐭𝐢𝐨𝐧 is not science fiction but a revolutionary concept; a cutting-edge approach that holds the potential to transform medicine as we know it. Check out our recent blog, where we have highlighted how we aim to empower targeted protein degradation with our 𝐏𝐑𝐎𝐓𝐀𝐂 𝐒𝐞𝐫𝐯𝐢𝐜𝐞𝐬, along with the power of E3 igase. Click here to read the complete blog - https://lnkd.in/dhuA5kfK #protac #targetedproteindegradation #tpd #drugdiscovery #synthesis #chemistry #biotech #seedingnewideas

Check out Fletcher Malcom's talk about the importance of upstream optimization for AAV production! #mirusbio #milliporesigma #bioprocessing #lifescience #biotech #genetherapy