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Commemorating a Pioneering Mind: James Parkinson and the "Shaking Palsy’ April 11th marks a day of remembrance and respect for translational scientists worldwide as we honor James Parkinson, born on this day in 1755. Over two centuries ago, Parkinson authored an essay that would lay the foundation for understanding a complex neurological disorder that now bears his name. His work, "An Essay on the Shaking Palsy," described with meticulous care a condition characterized by "involuntary tremulous motion, with lessened muscular power." Parkinson's observant eye detailed not just the shaking that so conspicuously marked the disorder, but he also delved into the patient’s world - the daily struggle against an unseen foe that bound the body even as the mind remained sharp. His essay wasn’t just a clinical report; it was a window into the lives of those affected, written with empathy and precision. Today, translational scientists wield advanced tools and harness vast computational power, to understand disease mechanisms and look for cures. The foundational work of those like Parkinson remind us of the human element at the core of these scientific endeavors. #JamesParkinson #ShakingPalsy #TranslationalScience #DrugDiscovery

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