Foundation For Prader-Willi Research’s Post

New research using human neurons identifies the scaffolding molecule #Gephyrin as critical for autonomous synapse formation in #GABAergic synapses, which are implicated in #neurological disorders like #epilepsy. https://lnkd.in/e7M379jy   Researchers at Colorado State University recently published their findings in PNAS: https://lnkd.in/eS4WvmVN #neuroscience #neurology #GABA #synapses #humanrelevantresearch #NAMs #nonanimalmethods

Discover how specific brain regions and neurotransmitters play a crucial role in the manifestation of OCD symptoms. From the orbitofrontal cortex to neurotransmitter dysregulation, we're uncovering the science behind this complex disorder. Genetic Factors: Learn about the growing evidence suggesting a genetic component to OCD and the interplay of genetic and environmental factors. Neuroimaging Insights: Explore how neuroimaging techniques have provided valuable insights into the structural and functional differences in the brains of individuals with OCD. Treatment Options: Understand the effective management of OCD through a combination of psychotherapy, medication, and lifestyle modifications. #OCDResearch #neurobiology #mentalhealthawareness #OCDRecovery https://lnkd.in/d-iXiMqk

Discover how specific brain regions and neurotransmitters play a crucial role in the manifestation of OCD symptoms. From the orbitofrontal cortex to neurotransmitter dysregulation, we're uncovering the science behind this complex disorder. Genetic Factors: Learn about the growing evidence suggesting a genetic component to OCD and the interplay of genetic and environmental factors. Neuroimaging Insights: Explore how neuroimaging techniques have provided valuable insights into the structural and functional differences in the brains of individuals with OCD. Treatment Options: Understand the effective management of OCD through a combination of psychotherapy, medication, and lifestyle modifications. #OCDResearch #neurobiology #mentalhealthawareness #OCDRecovery https://lnkd.in/ddsSX_Zc

Now out in Nature communications our study on "Regional patterns of human cortex development correlate with underlying neurobiology" integrating neurobiological brain atlases with normative modeling and population neuroimaging across lifespan:

I am thrilled to announce the opening call for the special issue titled Linear and non-linear Signals from the brain: from basic to clinical application on Current Alzheimer Research Journal [deadline for paper submission 28 July, 2024]  #eeg #fmri #nonlinear #alzheimersdisease #fractal #neuroscience #neurology

🔎 Colorado State University's insightful study into brain synapses and how they work has paved the way for potential treatments of neurological disorders. It gave several insights through its novel research method into synapse formation and function: 𝐏𝐫𝐨𝐭𝐞𝐢𝐧 𝐅𝐨𝐮𝐧𝐝𝐚𝐭𝐢𝐨𝐧: Synapses are primarily formed through a protein called Gephyrin. 𝐀𝐮𝐭𝐨𝐧𝐨𝐦𝐨𝐮𝐬 𝐃𝐞𝐯𝐞𝐥𝐨𝐩𝐦𝐞𝐧𝐭: Gephyrin plays a key role in the autonomous development of synapses, facilitating their formation without external guidance. 𝐌𝐮𝐭𝐚𝐭𝐢𝐨𝐧 𝐈𝐦𝐩𝐚𝐜𝐭: The study identified that several mutations in the Gephyrin protein are linked to various neurological disorders. 💊 These findings provide a deeper understanding of synaptic mechanisms and offer promising avenues for developing targeted treatments for neurological conditions. Read all about the study here: 🔗 https://lnkd.in/e7M379jy #Neuroscience #BrainResearch #Synapses #NeurologicalDisorders #ColoradoStateUniversity #BrainHealth #MedicalResearch

New blog post: Newly developed brain organoids with a fully functioning neural network will allow the most accurate reflection of in vivo conditions. The protocol to grow such organoids is freely available and the method will foster autism and schizophrenia research and related drug development projects. Read the full post 👇🏼 #drugdevelopment #neurology #autism #schizophrenia #research #blogpost https://lnkd.in/d37ai5qZ

I'm honoured to proclaim that I successfully completed the University of Chicago’s "Understanding the Brain: The Neurobiology of Everyday Life" course, which was conducted by the known Dr.Peggy Mason 🧠 Throughout the course, I gained a lot on a number of important topics such as Neurological Diseases to Investigate the root causes and effects associated with different types of brain diseases, Neuroanatomy which helped to understand the intricate structure and organization of the nervous system, Neural Communication to recognise how information is analysed and transmitted by the neurons functioning collectively and most importantly analysing how pharmaceutical substances influence neurological functions and disorders. My understanding of these complex topics has been much strengthened by this course,the abundant information significantly improved the learning experience. #neurology #pharmacology #neuroanatomy #neurologicaldisorders #cognitivescience #universityofchicago

🧠 Did you know that oligodendrocytes (OLs) play a critical role in brain health? OLs produce myelin sheaths that protect axons, and recent research from the University of Zurich has found that OLs respond to electrical signals of axons firing by increasing glucose consumption. The trigger for this response? Potassium. Studies with genetically modified mice lacking the Kir4.1 potassium channel showed significant axon damage over time. An exciting step towards understanding neurological disorders! Check out the breakthrough findings here: Nature Neuroscience: https://lnkd.in/ejwP4Zp3 Psypost Article: https://lnkd.in/eFsUHnQB #neuroscience #brainhealth #research #multiplesclerosis #alzheimers #discovery

💥 CNTN4 #Protein’s Role in #Autism and #Alzheimer’s Unveiled Source: University of Exeter 💥 A new study reveals the #crucial role of the protein Contactin-4 (#CNTN4) in #neuron #development, impacting both neurodevelopmental disorders and Alzheimer’s disease. Researchers found that CNTN4, linked to #autism, interacts with the #Alzheimer-related protein #APP, affecting #neuron growth in the brain’s cortex. #neuroscience #neurology #asd #genetics #autism #protein #healthtech #techforgood #digitalhealth #sd #alz #dementia #futureofhealthcare https://lnkd.in/etEegPkV