𝗦𝘁𝗲𝗿𝗶𝗹𝗲 𝗘𝗻𝗴𝗶𝗻𝗲𝗲𝗿𝗶𝗻𝗴 - 𝗔𝗶𝗿𝗳𝗹𝗼𝘄 𝘃𝗶𝘀𝘂𝗮𝗹𝗶𝘇𝗮𝘁𝗶𝗼𝗻 . . . Was discussing till now “Why” part of Airflow Visualization, in this post will elaborate more about “𝗪𝗵𝗮𝘁 𝗶𝘀 𝘁𝗵𝗲 𝗽𝘂𝗿𝗽𝗼𝘀𝗲 𝗼𝗳 𝘁𝗵𝗲 𝗔𝗶𝗿𝗳𝗹𝗼𝘄 𝗩𝗶𝘀𝘂𝗮𝗹𝗶𝘇𝗮𝘁𝗶𝗼𝗻” Purpose of doing Smoke Studies :- Ø Visualize the airflow pattern Ø Air is colorless and invisible – unless we suspend white particles in the air Ø Smoke is means of suspending marker particles in the air so that we can see what the air is doing. Ø Airflow Visualization:- Provides the visual records of actual airflow pattern in pharmaceutical facility. It is currently the most widely accepted method of demonstrating that airflow pattern in critical processing areas meets the regulatory expectations. Based on Airflow, Unidirectional or Turbulent, airflow visualization helps identifying nature of airflow. Determine further course of action based on Airflow visualization if it doesn’t meet the acceptance criteria. In upcoming post, will elaborate more about “How to perform the Airflow Visualization”. Keep commenting and keep giving feedback for improvement. #pharma #sterileprocessing #sterile #airflow #visualization #engineering #pharmaceutical The Aseptic Architect #theasepticarchitect Pharma's Trailblazer #pharmastrailblazer #gauravdakshini
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Lab automation market to hit $7.1B by 2028, 5.8% CAGR 𝐃𝐨𝐰𝐧𝐥𝐨𝐚𝐝 𝐏𝐃𝐅 𝐁𝐫𝐨𝐜𝐡𝐮𝐫𝐞-https://lnkd.in/dMhZmDga The global lab automation market in terms of revenue was estimated to be worth $5.1 billion in 2022 and is poised to reach $7.1 billion by 2028, growing at a CAGR of 5.8% from 2022 to 2028 Thermo Fisher Scientific TECAN GROUP Danaher Corporation Agilent Technologies F. Hoffmann-La Roche Ltd. PerkinElmer, Inc. Eppendorf Group BD Waters Corporation Siemens Healthineers bioMérieux Endress+Hauser Group Hamilton Company Hudson Robotics, Inc. Gilson BMG LABTECH Aurora Biomed Inc. Peak Analysis and Automation FORMULATRIX QIAGEN N.V. LabVantage Solutions, Inc. Bio-Rad Laboratories LabWare Analytik Jena
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Digital twins—computer simulations used to design, test, and fine-tune physical processes—are made up of three components: a physical system, a digital infrastructure and, most importantly, a virtual system or model. #JLLLifeSciences #biotech #pharma #medtech
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Hi fi twins: scale down models that match your GMP process...
Hi fi twins: scale down models that match your GMP process We know about scale down models, but what about Hi Fidelity Twins that accurately represent your GMP process? Traditional low fidelity mimics fail to capture real world manufacturing conditions, increasing risk and leading to expensive delays. But Hi fi twins are faithful scale down models of manufacturing processes. Think “GMP in a box” for process development. Hi fi twins give confidence in critical early decision making about candidate selection, media and reagent screening, process performance, product quality and scalability. Hi fi twins are mini bioreactors, purification columns and other systems that accurately replicate upstream and downstream GMP conditions at a small or ultra small scale, whilst still enabling development at low cost and high speed. Unlike low fidelity mimics, high fidelity twins accurately account for geometries, fluid dynamics, gassing strategies, CO2 stripping, specific power inputs, KLAs and more besides. They can be precisely configured to your unique requirements to enable faster, better and cheaper transitions from shake flasks to real manufacturing conditions. Biology is complex and performs very differently in low fi mimics and often leads to risky decisions that with hindsight turn out to be wrong, wasting precious resources. But biology built on Hi fi twins gives detailed knowledge of how biology performs in true manufacturing conditions, so critical early decisions are made with the evidence based confidence that leads to patient success. Talk to us about Hi fi twins today at info@biologic.tech.com. Follow BiologIC Technologies on LinkedIn for more content about the latest advanced bioprocessing systems. #GMPinabox #HiFiTwin #Bioprocessing #UltraScaleDown #Biomanufacturing #ProcessDevelopment
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Knowledge-Based Digital Twins Benefit Biopharma Process Developers Most digital twins use empirical models created from observed relationships between process inputs and outputs, providing insights into the behavior of a production process without the need for in-depth understanding, in theory making them more straightforward to build. While this fits with ideas like Quality by Design, it is more labor intensive than it needs to be, and hybrid models may be a better option.
Knowledge-Based Digital Twins Benefit Biopharma Process Developers
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Section Head HVAC & Utility @ Lupin limited | QMS & VALIDATION | Maintenance & Projects(OSD,INJ& DERMA)| EX MANKIND/ALEMBIC/KIRLOSKAR
6moSir, are there HEPA in return also as depicted in figure