Genova Diagnostics’ Post

📣 We are very happy to share our latest research with the world: "Biochemical characterisation of a cassava diversity panel for post-harvest physiological deterioration (PPD)" in Journal of Plant Physiology. 📣 This research is part of a longstanding collaboration with CIAT as part of Roots, Tubers and Bananas Breeding - CGIAR and showed that even small amounts of b-carotene (~20μg/g dry weight) can significantly reduce the PPD response of cassava roots. The metabolite profiling of four cassava populations over two years highlighted a strong correlation between PPD and phenylpropanoid derived compounds. And the population approach helped to understand the biological variation involved in the PPD response. Hopefully, this will contribute to the understanding of PPD and how it can be overcome to improve the shelf-life and market potential of cassava! #Cassava #PPD #RTBcrops #Metabolomics

Bacillus licheniformis on CBA. This is a common soil bacteria, named licheniformis because it looks like lichen when grown. Although rarely pathogenic in humans, it can cause food spoilage and food poisoning if ingested. #microbiology #medical #bacteriology #bacteria #laboratory #laboratorytechnician #microbiologylab #biotechnology #genetic #virology #bacterial

Serratia ficaria identified with MALDI TOF MS (Mabriteccentral.com) 🦠🕵🏼♂️ 🌳 💀 #microbes #microbiology #mabriteccentral #MALDITOF #Bruker #Shimadzu #bioMérieux Serratia ficaria, a lesser-known member of the Enterobacteriaceae family, might just be the most unassuming party crasher in the microbial world. Originally discovered hanging out in fig trees, this bacterium has occasionally gatecrashed human clinical samples, showing up in places like gallbladders and leg ulcers. Despite its rare appearances in medical settings, S. ficaria remains a bit of a mystery, often misidentified or flying under the radar due to its non-pigmented, lactose-negative colonies that emit a potatolike odor. This bacterium's claim to fame? It's not just a figment of your imagination—it's a fig-ment of reality! Found primarily in fig tree ecosystems, S. ficaria has a knack for popping up in fig-related infections, making it a fig-ure of interest in both botanical and medical circles. While it might not be the life of the party in the microbial community, its ability to sneak into human hosts through fig consumption adds a twist to its otherwise low-profile existence. So, next time you're enjoying a fig, remember Serratia ficaria: the microbe that likes to keep it fig-ureal! Mabriteccentral.com in combination with MALDI-TOF MS is a great tool for microbial-monitoring purposes since it includes many environmental bacteria not found in any other commercially available MALDI database.

Freeze drying assumes a pivotal role in the preservation and protection of microbiomes, offering researchers an invaluable tool for their scientific quest into the human microbiome's mysteries. Learn more https://lnkd.in/eiHZJ7Hj #Freezedrying #microbiomes #humanmicrobiome #microbial #microbiome #preservation #bacteria, #fungi #microorganisms #lyophilization #microbiomepreservation #Biotherapeutic #LBPs #microbiomeresearch

We are thrilled to invite you to our upcoming webinar titled "The Microbial Wonderland," happening tomorrow, June 28th, from 7:00 PM to 8:00 PM IST. 🦠🔬 🌟This is an exclusive opportunity to delve into the fascinating world of microbes and their incredible impact on our lives.🌟 Seats are filling up quickly, and we don’t want you to miss out on this enlightening session. Ensure your spot by registering online as soon as possible.🌍✨ #MicrobialWonderland #BacterialConjugation #GeneticTransfer #HorizontalGeneTransfer #AntibioticResistance #VirulenceFactors #MicrobialEvolution #ScienceWebinar #Microbiology #LearnWithUs

Epigallocatechin Gallate (ECGC)- Important Bioactive From Plants! Epigallocatechin Gallate (EGCG) is a type of catechin, a flavonoid, which belongs to the class of polyphenolic compounds. Chemically, it is characterized by three phenol rings and multiple hydroxyl groups, which contribute to its strong antioxidant properties. EGCG is notably abundant in green tea (Camellia sinensis) and is also found in smaller amounts in other foods such as white tea, black tea, and certain fruits like apples and plums. Among its possible health benefits: ·     Antioxidant ·     Antiinflammatory ·     Anticancer ·     Cardioprotective ·     Antimicrobial ·     Neuroprotective ·     Antidiabetic ·     Antiobesity ECGC is thought to reduce inflammation and prevent chronic conditions, such as heart disease, effects of diabetes, some cancers, as well as aiding weight loss. One area of research has been uncovering its neuroprotective effects. In a recent study published in 2023, researchers explored the impact of EGCG on Alzheimer's disease. The study found that EGCG inhibited the formation of beta-amyloid plaques, a hallmark of Alzheimer's pathology, and enhanced the clearance of existing plaques. The researchers also discovered that EGCG improved cognitive function in animal models of Alzheimer's, suggesting that it might slow or even prevent the progression of the disease in humans. #bioactives #medicinalplants #phytochemicals #ethnobotany #biodiversity #phytochemistry #ECGC *This post is for educational purposes only. It is not intended to diagnose, cure or treat any disease. Always seek medical advice directly through consultation with a health professional.   

Alteration of hormonal levels in a rootless epiphytic bromeliad in different phenological phases https://t.co/IXevhwP6y9 #EurekaMag

Soil microbes

I have studied the endocannabinoid system for 10 years now. I have read THOUSANDS of research papers about it. My understanding was that it was common to vertebrates but not necessarily ALL life. This morning I am studying the process of how endocannabinoids are formed and from the WIKI definition of NAE's I see this: "The endocannabinoid signaling system (ECS) is the major pathway by which NAEs exerts its physiological effects in animal cells with similarities in plants, and the metabolism of NAEs is an integral part of the ECS,[5] a very ancient signaling system, being clearly present from the divergence of the protostomian/deuterostomian,[6][7] and even further back in time, to the very beginning of bacteria, the oldest organisms on Earth known to express phosphatidylethanolamine, the precursor to endocannabinoids, in their cytoplasmic membranes. Fatty acid metabolites with affinity for CB receptors are produced by cyanobacteria, which diverged from eukaryotes at least 2000 million years ago (MYA), by brown algae which diverged about 1500 MYA, by sponges, which diverged from eumetazoans about 930 MYA, and a lineages that predate the evolution of CB receptors, as CB1 – CB2 duplication event may have occurred prior to the lophotrochozoan-deuterostome divergence 590 MYA. Fatty acid amide hydrolase (FAAH) evolved relatively recently, either after the evolution of fish 400 MYA, or after the appearance of mammals 300 MYA, but after the appearance of vertebrates. Linking FAAH, vanilloid receptors (VR1) and anandamide (NAE 20:4) implies a coupling among the remaining ‘‘older’’ parts of the endocannabinoid system, monoglyceride lipase (MGL), CB receptors, that evolved prior to the metazoan–bilaterian divergence (ie, between extant Hydra and leech), but were secondarily lost in the Ecdysozoa, and 2-Arachidonoylglycerol (2-AG).[8]" https://lnkd.in/gMFTfUfY WOW! I had no idea it was so prevalent in even CYANObacteria. Is this HOW pathogens interface with us?

The metabolism of 4-aminobutyrate (GABA) in fungi Most fungi utilize GABA both as a carbon and a nitrogen source. Fungal endogenous GABA largely originates from the decarboxylation of L-glutamate and is associated with sporulation/spore metabolism