Gianna Iantosca, MBA’s Post

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Is Biotech entering into a recovery phase? Off the back of two very successful IPOs from CG Oncology and ArriVent Biopharma last week, the below article from Fierce explores some of the positive signs that the industry will be moving back in the right direction following a historically slow year for biotech IPOs in 2023. Of course, IPOs are only one piece of the pie, and we need to also be monitoring M&A, and VC/PE activity following JPM a few weeks ago. That being said, a little bit of "cautious optimism" is certainly refreshing at this stage. Curious what the general feeling is on the outlook for the remainder of the year from any connections who attended JPM? Great job to Max Bayer and the team at Fierce. Fingers crossed.

This is exciting news from the biotech IPO market! Following CG Oncology's successful debut on Nasdaq, ArriVent BioPharma has now entered the spotlight with its own upsized offering. ArriVent's business model, focused on in-licensing clinical stage assets from emerging biotech hubs and bringing them to the US market, signals a promising trend in the industry. While ArriVent's offering landed within its expected range, the company sold 9.7 million shares, surpassing its initial plan and raising gross proceeds of $175 million, exceeding expectations. With the potential for even more growth if underwriters exercise their option, ArriVent's journey on the Nasdaq, under the ticker "AVBP," promises to be an exciting one. CG Oncology's recent success adds to the anticipation, as the biotech market shows signs of opening up in 2024. Other biotechs like Alto Neuroscience, Metagenomi, and Kyverna Therapeutics poised are poised to join what could be a biotech IPO wave this year. #BiotechIPO #ArriVentBioPharma #InLicensing #Nasdaq #EmergingBiotech ArriVent takes in $175M from second biotech IPO of the year

**Biotech IPO Cost Comparison: Who Spends the Most to Go Public? ** Going public is a major milestone for any company, but it comes with a hefty price tag. Let's dive into the IPO costs of six biotech companies from FY24: Kyverna, Cargo Therapeutics, CG Oncology, Alto Neurosciences, Arrivent Biopharma, and Metagenomi. The Numbers Don't Lie: Kyverna Therapeutics $3.8M ($319M IPO) CARGO Therapeutics $5.3M ($281M IPO) CG Oncology $5.5M ($380M IPO) Alto Neurosciences $4.5M ($128M IPO) ArriVent Biopharma $3.8M ($175M IPO) Metagenomi $6.1M ($94M IPO) Biggest Spenders: Metagenomi takes the crown for highest total spend, shelling out a whopping $6,091,955! Legal fees ⚖️ were a major cost driver for them, clocking in at a staggering $2,695,030. Budget-Conscious Champions: Kyverna and Arrivent Biopharma come in at the lower end of the spectrum, keeping their costs below $4 million. Smart legal strategies or a more streamlined IPO process? Fees in Focus: Accounting fees seem to be pretty consistent across the board, ranging from $800,000 to $1,200,000. But legal fees ⚖️ show wider variation, with Metagenomi's hefty bill being an outlier. Transfer agent fees also differ significantly, with Metagenomi again spending the most ($1,887,850) and Alto Neurosciences spending the least ($5,000). Remember: These are just a few insights from the data. Every IPO is unique, and there are many factors that can affect costs, such as company size, industry, and regulatory environment. What do you think? Which costs surprised you the most? Share your thoughts in the comments below! #IPO #Biotech #Costs #Analysis

🚀 Is the biotech fundraising drought finally over? January's numbers say YES – with over $6 billion raised by visionary drug developers! 🌟 Let's celebrate these incredible milestones together: 🎉 Huge congrats to CG Oncology for their stellar $380 million IPO, skyrocketing from $19 to $43 per share! 🍄 And a round of applause for Lykos Therapeutics (formerly MAPS PBC), blazing trails with a groundbreaking $100 million series A, fueling the psychedelic revolution with style! 💡 Eyconisa, an Ascendis Pharma spin out, wows with a dazzling $150 million series A, backed by powerhouse investors like Frazier Life Sciences, RA Capital Management, venBio, and HealthQuest Capital! 💰 Cour Pharmaceuticals Development Co., Inc. joins the party with a bang, closing a remarkable $105 million series A, led by Lumira Ventures and Alpha Wave Global! 🔥 ArriVent Biopharma stuns the market with a $175 million IPO, surpassing expectations and setting a new standard for success! And although it was in February I have to mention Kyverna Therapeutics's jaw-dropping $319 million IPO – smashing their goal and pointing towards a future of transformative autoimmune cell therapy! With these groundbreaking achievements, can we finally say good times are ahead? It's about time! 😎💫 #BiotechRevolution #InnovationUnleashed #biotech #future

Kyverna Therapeutics aims to be the fifth biotech to IPO in 2024 as the autoimmune CAR-T cell therapy maker sets its sights on $182 million in net proceeds from a listing as “KYTX.”... ... CG Oncology and ArriVent Biopharma kicked things off last week with upsized offerings and strong first days. Alto Neuroscience and Fractyl Health are expected to float in the coming days... ...Kyverna is one of the early movers in the autoimmune CAR-T cell therapy space... KYV-101, licensed from the The National Institutes of Health , is already in the clinic for lupus nephritis...... #autoimmunedisease #clinicaltrials #lupus #lupustherapies #earlymover #IPO #publicmarkets #financing #funding #biotech #biotechnology #pharmaceutical #pharma #lifesciences #therapeutics #cellandgenetherapy #celltherapy #advancedtherapies #regenerativemedicine #182m #funding2025 Peter Maag Vida Ventures, LLC Westlake Village BioPartners® Gilead Sciences Northpond Ventures Bain Capital RTW Investments, LP ElevateBio Oxford Biomedica #carttherapies

CG Oncology is hoping for a $209m IPO, with more biotechs looking to hit public markets this year. Bladder cancer-focused CG started 2024 by outlining IPO plans, but no figures were offered at the time. Now, the biotech has said it is looking to sell 11.8 million shares at $16-18 a piece, bringing the total IPO value to around $181.1million. If the underwriters jump at the opportunity to snap up a further 1.7m shares, then the haul would rise to $209million. Will we be seeing a bolder year for bitoech in 2024? #biotech #pharma #mergersandacquisitions

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Big news in biotech! Zenas BioPharma is planning a $200M IPO to fund its ongoing and future trials targeting a range of autoimmune diseases. With this substantial raise, Zenas aims to advance its pipeline of innovative treatments and tackle conditions that currently have unmet medical needs. This move marks a significant step forward in their mission to bring life-changing therapies to patients worldwide. Exciting times for biotech innovation! #IPO #biotech #healthcareinnovation

Gene&Cell Therapy >> Former RayzeBio CEO quickly returns with new biotech; Amgen’s global research leader steps down: Ken Song Ken Song is back in business. He left RayzeBio in February after leading the radiopharmaceuticals startup from Series A to IPO in three years, and then a $4.1 billion exit to Bristol Myers Squibb just months after that Nasdaq debut. Now, he’s founder, chair and CEO of a new biotech called Candid Therapeutics, according to his LinkedIn. The roles started in May, according to his profile on the job networking site. The company is working on biologics in the autoimmune field, according to a job posting. With about two decades of leadership experience at biotech startups, a diagnostics company and a healthcare VC firm, Song is ready for his next post. “I’ve actually been looking at quite a few things already. I love that part of just building and pursuing innovation,” Song told Endpoints News in early March. “I’m usually not one to sit idle, so I have been looking at a fair number of different potential interesting opportunities on the company side. I’m unlikely to go back to being an investor.” It’s unclear who is funding Candid at this time. The RayzeBio deal led to a big payday for Song. The cash value of shares he and his family trust beneficially owned came out to $101 million, according to an SEC filing on Bristol Myers’ tender offer. He also had about $70 million in cash value from “in-the-money options,” according to the paperwork. — Kyle LaHucik Ray Deshaies → Amgen SVP of global research Ray Deshaies wrote on LinkedIn that Angela Coxon will take over his role on an interim basis. Coxon has been with Amgen since 1999 and spent the last three years as VP of discovery oncology research. In his LinkedIn post, Deshaies touched on some of the molecules that defined his tenure: the KRAS G12C drug sotorasib (now marketed as Lumakras), the obesity candidate MariTide and the siRNA heart drug olpasiran, among others. “Stepping down from my leadership role has led me to reflect on my time at Amgen over the past 7 years. This reflection has triggered two emotions: gratitude and pride,” he said. “It has been a tremendous privilege to have such an awesome set of colleagues as I have been blessed with at Amgen. It has been an experience — and opportunity — of a lifetime.” Eric Cox → As momentum builds with its Boehringer Ingelheim-partnered weight loss drugs, Zealand Pharma has selected Eric Cox as chief commercial officer. He begins on Aug. 5 and comes from Carmot Therapeutics, where he was VP, commercial strategy and business development. Roche’s $2.7 billion deal for Carmot is off to an auspicious start with early readouts for two obesity drugs, CT-388 and CT-996. Cox had a 16-year career with Merck before his appointment at AstraZeneca as US commercial franchise leader responsible for… #lucidquest #genetherapy #celltherapy