In this week's #techNoteTuesday, we looked at ADCs. Join us next week to learn how AstraZeneca reduces charge heterogeneity analysis from weeks to minutes and fully characterizes ADCs using the SCIEX IntabioZT icIEF-UV/MS system. Register here for August 29th https://lnkd.in/eFjRwtTq. The SCIEX IntabioZT not only provides simultaneous imaged cIEF optical and MS data for rapid quantification and identification of charge variants, but it also uncovers variants not seen by other separation techniques, providing unprecedented characterization of protein-based biotherapeutics. Register here for August 29th, https://lnkd.in/eFjRwtTq #massspectrometry #massspec #biopharma #icIEFUVMS #proteins #antibodydrugconjugates #antibodydiscovery
Learn how AstraZeneca reduces charge heterogeneity analysis from weeks to minutes and fully characterizes ADCs using SCIEX IntabioZT icIEF-UV/MS system. Identify and monitor charged modifications on ADC payloads and disentangle the contribution of the payload from the antibody modifications. Register here for August 29th, https://lnkd.in/eFjRwtTq #massspectrometry #massspec #biopharma #icIEFUVMS #proteins #antibodydrugconjugates #antibodydiscovery