i3S - Instituto de Investigação e Inovação em Saúde’s Post

For Better Science: This guest blog by Sholto David regarding science fraud in the billion dollar cancer research industry is enlightening and disturbing, delving into the research of prestigious professors, researchers and executives. PubPeer is shown to be a valuable resource as well. https://lnkd.in/gHgj-WFh

IN THE NEWS Whether or not you're taking the day off today, podcasts are a great companion when running errands or during commutes, and we have a great suggestion for you: "Palavra de Cientista". Of course, we have ulterior motives behind this suggestion: the latest episode features #i3S researcher Joana Gomes, who talks at length about the work she conducts in the Glycobiology in Cancer group. 🎧🎙️ 👇   #i3Snews #i3Sresearch #i3Sinnovation #cancer #cancerresearch #collab #ICBAS

Shocking Allegations of Research Misconduct at Dana-Farber/Harvard A recent article by Sholto David in Forbes raises serious concerns about potential research misconduct at the Dana-Farber Cancer Institute (DFCI) at Harvard University. The article details several instances of published research containing manipulated data, casting a shadow over the integrity of the institution's scientific output. While some of the researchers involved have responded to the criticisms, the article argues that DFCI and Harvard have not taken adequate steps to address these concerning issues. This lack of transparency and accountability is deeply troubling and demands a thorough investigation to ensure the credibility of future research conducted at these esteemed institutions. https://lnkd.in/e6wEUb7U Another article from Nature's concerning integrity of data. https://lnkd.in/eR2js8mU #scienceintegrity #researchmisconduct #DFCI #Harvard

➡ A team of researchers of Instituto de Biofísica e Engenharia Biomédica - Institute of Biophysics and Biomedical Engineering and professors of Faculdade de Ciências da Universidade de Lisboa, with partners from the University of Galway and Politecnico di Torino have just seen their "3BAtwin" Twinning application accepted for funding of 1.5M€ ! Congratulations to all! 💪 ☝ The main goal for this twinning project is to enhance the capabilities of the coordinating entities - IBEB and CIÊNCIAS/ULisboa - by providing them with specific and refined knowledge as well as tools. The aim is to expedite the transition of medical microwave imaging (MMWI) from the research bench to the patient's bedside. As a result, the consortium will address the following MMWI applications in their exploratory research project: Bone osteoporosis and Bone cancer, Brain ischemic and hemorrhagic strokes, Breast cancer and metastasized Axillary lymph nodes (3BAtwin). #science #twinning #research #fcul #cienciasulisboa

⬇ 🔬 𝐄𝐱𝐜𝐢𝐭𝐢𝐧𝐠 𝐧𝐞𝐰𝐬! Human embryonic lung organoids have been successfully captured using the EzScope system (https://lnkd.in/ddwiq3iu). ⭐ 👩🔬 "𝑇ℎ𝑒 𝑖𝑚𝑎𝑔𝑖𝑛𝑔 𝑚𝑖𝑐𝑟𝑜𝑠𝑐𝑜𝑝𝑒 𝑓𝑜𝑟 𝑖𝑛𝑐𝑢𝑏𝑎𝑡𝑜𝑟𝑠 ℎ𝑎𝑠 𝑏𝑒𝑒𝑛 𝑎 𝑣𝑎𝑙𝑢𝑎𝑏𝑙𝑒 𝑡𝑜𝑜𝑙 𝑖𝑛 𝑜𝑢𝑟 𝑙𝑎𝑏𝑜𝑟𝑎𝑡𝑜𝑟𝑦, 𝑎𝑙𝑙𝑜𝑤𝑖𝑛𝑔 𝑢𝑠 𝑡𝑜 𝑎𝑐𝑐𝑢𝑟𝑎𝑡𝑒𝑙𝑦 𝑐𝑎𝑝𝑡𝑢𝑟𝑒 𝑡ℎ𝑒 𝑑𝑖𝑓𝑓𝑒𝑟𝑒𝑛𝑡𝑖𝑎𝑡𝑖𝑜𝑛 𝑝𝑟𝑜𝑐𝑒𝑠𝑠 𝑜𝑓 ℎ𝑢𝑚𝑎𝑛 𝑒𝑚𝑏𝑟𝑦𝑜𝑛𝑖𝑐 𝑙𝑢𝑛𝑔 𝑜𝑟𝑔𝑎𝑛𝑜𝑖𝑑𝑠 𝑖𝑛𝑡𝑜 𝑎𝑙𝑣𝑒𝑜𝑙𝑜𝑠𝑝ℎ𝑒𝑟𝑒𝑠-𝑙𝑖𝑘𝑒 𝑠𝑡𝑟𝑢𝑐𝑡𝑢𝑟𝑒𝑠 𝑓𝑜𝑙𝑙𝑜𝑤𝑖𝑛𝑔 𝑡𝑟𝑎𝑛𝑠𝑓𝑒𝑐𝑡𝑖𝑜𝑛 𝑤𝑖𝑡ℎ 𝐼𝐺𝐹𝐵𝑃3 𝑠𝑖𝑅𝑁𝐴. {...} 𝑇ℎ𝑒 𝑒𝑎𝑠𝑒 𝑜𝑓 𝑢𝑠𝑒 𝑎𝑛𝑑 𝑡ℎ𝑒 𝑞𝑢𝑎𝑙𝑖𝑡𝑦 𝑜𝑓 𝑡ℎ𝑒 𝑖𝑚𝑎𝑔𝑒𝑠 𝑜𝑏𝑡𝑎𝑖𝑛𝑒𝑑 𝑤𝑖𝑡ℎ 𝑡ℎ𝑒 𝐸𝑧𝑆𝑐𝑜𝑝𝑒 ℎ𝑎𝑣𝑒 𝑖𝑚𝑝𝑟𝑜𝑣𝑒𝑑 𝑡ℎ𝑒 𝑝𝑟𝑜𝑑𝑢𝑐𝑡𝑖𝑣𝑖𝑡𝑦 𝑜𝑓 𝑜𝑢𝑟 𝑒𝑥𝑝𝑒𝑟𝑖𝑚𝑒𝑛𝑡𝑠". We're honored that our technology contributed to the latest research published by the Molecular Oncology and Embryology Group from Hospital Clínic de Barcelona. Congratulations on the publication Melissa Acosta Plasencia and Alfons Navarro 🎉 🔗Discover more about this groundbreaking study here: https://lnkd.in/dPGetDCS Read more here 📑: https://lnkd.in/dqp6WYd7 #LungCancer #Research #OrganoidGrowth

Great medical paper Sonic hedgehog (Shh) directs early gut patterning via epithelial–mesenchymal signaling and remains expressed in endoderm-derived tissues into the adult period. In human adult gut epithelium SHH/SHH expression is strongest in basal layers, which suggests that SHH may function in the maintenance of gut epithelial stem or progenitor cells. For information only please speak to your registered medical professional #ehlersdanlos #ibd #gastroenterology #gastroentologist #oncology #guthealth #gutmicrobiome

A breakthrough in brain research, Utrecht' scientists from various institutions, have cultivated mini-brains directly from human fetal brain tissue. These 3D mini-organs offer a revolutionary approach to studying brain development and hold potential for researching diseases like brain tumors. The organoids, exhibiting valuable characteristics, also show promise in cancer drug studies. This groundbreaking work enhances experiment reliability and provides new insights into healthy and aberrant brain development. #organoids #healhtypeople #UtrechtHeartofHealth https://lnkd.in/edraJTrk

🏅 Congratulations to Chiara Lago, one of the recipients of the #ibidi Paper Award 2024 in 3️⃣D Cell Culture Research! 🏆 👩🔬 Chiara, a postdoctoral researcher at the Armenise-Harvard Laboratory of Brain Disorders and Cancer at the Università di Trento, Italy, was honored for her first-author publication in #EMBO Molecular Medicine. Her paper, titled "Patient- and Xenograft-Derived Organoids Recapitulate #Pediatric Brain Tumor Features and Patient #Treatments", impressed our external #jury with its innovative approach. 🎓 ⚗ 🔬 Chiara’s work focuses on developing patient-derived organoid (#PDO) models for pediatric brain #cancer, which are crucial for studying tumor biology and testing new #therapies. Her study introduces a novel method for generating PDOs and patient-derived #xenograft organoids (PDXOs) through mechanical cutting, rather than enzymatic dissociation, offering significant advancements in the field. 🎉 Find out more about Chiara and her impactful research here: https://zurl.co/5vzA 🤩 The award was proudly presented by Mario Barlocco of Twin Helix, our esteemed partner in Italy. #congratulations #ibidipaperaward #organoids #embo #cancerresearch #technology #innovation

📺 𝐘𝐨𝐮𝐭𝐮𝐛𝐞 𝐯𝐢𝐝𝐞𝐨𝐬📺 If you want free Gynecology oncology, Endometriosis, or Neuropelveology masterclasses, subscribe to Professor Marc Possover Youtube channel. More videos are under preparation 🌝 https://lnkd.in/eQv_w_h8 #neuropelveology #oncology #endometriosis #gynecology