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Ophthopedia Update:Primary care optometry-based diabetic retinopathy review clinics – a new model of care and comparison with virtual diabetic retinopathy clinics: Eye, Published online: 29 June 2024; doi:10.1038/s41433-024-03211-0Primary care optometry-based diabetic retinopathy review clinics – a new model of care and comparison with virtual diabetic retinopathy clinics #Ophthalmology #Eye #Ophthotwitter

January marks Glaucoma Awareness Month, to shed light on a silent threat to vision. The purpose of this month is to educate and encourage individuals to prioritize eye health, emphasizing the importance of early detection and intervention in managing glaucoma. Glaucoma is often called “the silent thief of sight” and it affects over 60 million people worldwide. It is estimated that nearly half of those with glaucoma are unaware of their condition. As a leading cause of irreversible blindness, glaucoma poses a significant public health challenge. However, awareness and proactive measures can make a substantial difference. Glaucoma typically develops gradually, often without noticeable symptoms in the early stages. Vision loss starts from the periphery, making it challenging to detect. As the condition progresses, individuals may experience tunnel vision, eye pain, headaches, and blurred vision. Regular eye check-ups are crucial for early detection, especially for those at higher risk due to age, family history, or other health conditions. While glaucoma has no cure, early detection allows for effective management to slow its progression and preserve vision. Treatment options include prescription eye drops, oral medication, laser therapy, or surgery in advanced cases. Timely intervention can prevent or minimize vision loss, underscoring the importance of regular eye examinations as a proactive step in maintaining eye health. GCT is an expert in conducting Ophthalmology clinical trials, please contact us at bd@gctrials.com to learn more. https://lnkd.in/d8SjYV77 #GCT_awareness #GlaucomaAwarenessMonth #Glaucoma #sight #GCT #GlobalClinicalTrials #CRO #clinicalresearch #drugdevelopment #medicine #pharma #clinicaltrials #clinicaltrial #gctrials #research #ophthalmology #vision

A study published in JAMA Ophthalmology found that vision-related quality of life declined with the presence and severity of diabetic retinopathy (DR). What is vision-related quality of life? It's a measure of how eye conditions impact an individual's daily life, emphasizing the importance of interventions to reduce progression of DR at both early and more advanced stages. Check out this Healio article to learn more: https://hubs.la/Q02wY8Kt0 #DigitalDiagnostics #LumineticsCore #Healthcare #Eyecare

ICYMI: Cornea Update: Selective Endothelialectomy in Peters Anomaly: A Novel Surgical Technique and Its Clinical Outcomes in Children: Purpose: This study describes the surgical outcomes of selective endothelialectomy in Peters anomaly (SEPA), a relatively new technique to manage Peters anomaly (PA). Methods: This study included 34 eyes of 28 children who had a visually significant posterior corneal defect due to PA and underwent SEPA between 2012 and 2019. A selective endothelialectomy from the posterior corneal defect was performed while preserving Descemet membrane. The primary outcome measure was the resolution of corneal opacification. The secondary outcome measures were functional vision, complications, and risk factors for failure. Results: At a mean postoperative follow-up of 0.96 ± 0.20 years, 29 eyes (85.3%) maintained a successful outcome. Mean preoperative and postoperative best-corrected visual acuities were 2.55 ± 0.13 and 1.78 ± 0.13 (P < 0.0001), respectively. Ambulatory functional visual improvement was seen in 97%, and 23% attained vision ranging between 20/190 and 20/50. Corneal opacification failed to clear in 5 eyes (15%). Risk factors associated with surgical failure were female sex (P = 0.006), disease severity (P < 0.0001), glaucoma (P = 0.001), and additional interventions after SEPA (P = 0.002). In multivariate analysis, only disease severity (ie, a type 2 PA) was a significant risk factor for the failure of SEPA. There were no sight-threatening complications. Conclusions: SEPA is a safe and effective technique in select cases of posterior corneal defect due to PA. SEPA could be a potential surgical alternative to pediatric keratoplasty or optical iridectomy in children with central corneal opacification smaller than 7 mm due to PA. http://dlvr.it/T3jy7f #Cornea #MostPopularArticles #Ophthalmology

Outcomes of Trabeculectomy and Ahmed Glaucoma Valve Implantation in ICE Syndrome A recent study published in the Journal of Glaucoma examined the outcomes of trabeculectomy and Ahmed glaucoma valve (AGV) implantation in patients with iridocorneal endothelial (ICE) syndrome and secondary glaucoma. Let's break down the findings and their implications for patient care! Interactive Questions & Answers: Q1: What is iridocorneal endothelial (ICE) syndrome? A1: ICE syndrome is a rare eye disorder characterized by abnormal corneal endothelial cell proliferation, leading to secondary glaucoma, iris abnormalities, and corneal edema. Q2: What were the main findings regarding intraocular pressure (IOP) control in this study? A2: Both trabeculectomy and AGV significantly reduced intraocular pressure at all time points, but patients required more medications at the last follow-up compared to 6 and 12 months. Case Study & Answer: Case Study: Mark, a 50-year-old man diagnosed with ICE syndrome and secondary glaucoma, underwent AGV implantation. Over the next two years, his IOP remained controlled, but he needed more medications over time. By the fifth year, Mark's IOP control started to decline, and he developed corneal decompensation requiring graft surgery. Q: How did Mark's experience align with the study findings? A: Mark's case reflects the study's findings that both trabeculectomy and AGV can effectively reduce IOP initially, but there's a high risk of corneal decompensation and the need for increased medications and potential additional surgeries over time. Call to Action: If you or someone you know is affected by ICE syndrome and secondary glaucoma, discuss with your ophthalmologist the potential outcomes and long-term risks of trabeculectomy and AGV implantation. Interactive Poll: Are you familiar with the surgical options for managing glaucoma secondary to ICE syndrome? Yes, I know about trabeculectomy and AGV. No, I’m hearing about them for the first time. I have some knowledge but need more information. I’m not sure what ICE syndrome is. Hashtags: #Glaucoma #ICEsyndrome #Ophthalmology #Trabeculectomy #AhmedValve #IntraocularPressure #EyeHealth #CornealDecompensation #PatientCare #MedicalResearch Talk to your eye specialist about the best treatment options for managing glaucoma and share your experiences with us!

ICYMI: Cornea Update: Selective Endothelialectomy in Peters Anomaly: A Novel Surgical Technique and Its Clinical Outcomes in Children: Purpose: This study describes the surgical outcomes of selective endothelialectomy in Peters anomaly (SEPA), a relatively new technique to manage Peters anomaly (PA). Methods: This study included 34 eyes of 28 children who had a visually significant posterior corneal defect due to PA and underwent SEPA between 2012 and 2019. A selective endothelialectomy from the posterior corneal defect was performed while preserving Descemet membrane. The primary outcome measure was the resolution of corneal opacification. The secondary outcome measures were functional vision, complications, and risk factors for failure. Results: At a mean postoperative follow-up of 0.96 ± 0.20 years, 29 eyes (85.3%) maintained a successful outcome. Mean preoperative and postoperative best-corrected visual acuities were 2.55 ± 0.13 and 1.78 ± 0.13 (P < 0.0001), respectively. Ambulatory functional visual improvement was seen in 97%, and 23% attained vision ranging between 20/190 and 20/50. Corneal opacification failed to clear in 5 eyes (15%). Risk factors associated with surgical failure were female sex (P = 0.006), disease severity (P < 0.0001), glaucoma (P = 0.001), and additional interventions after SEPA (P = 0.002). In multivariate analysis, only disease severity (ie, a type 2 PA) was a significant risk factor for the failure of SEPA. There were no sight-threatening complications. Conclusions: SEPA is a safe and effective technique in select cases of posterior corneal defect due to PA. SEPA could be a potential surgical alternative to pediatric keratoplasty or optical iridectomy in children with central corneal opacification smaller than 7 mm due to PA. http://dlvr.it/T7sQvx #Cornea #MostPopularArticles #Ophthalmology

https://lnkd.in/gkP2mPEC                                                                                  Article title: Endovascular Interventions for Infra-Inguinal Arterial Disease: Collecting Evidence to Expand Indications   Author(s): Alfredo Augusto Eyer Rodrigues and Erlon Oliveira de Abreu-Silva* Journal: International Journal of Vascular Surgery and Medicine   Journal ISSN: 2455-5452 Editorial: Peripheral arterial disease (PAD) is a common manifestation of atherosclerosis, with a prevalence of 29% in those older than 70 years or aged 50-70 years who are either smokers or diabetic [1,2]. The majority of persons with this condition are asymptomatic, and less a fifth report typical intermittent claudication [3]. The literature shows us that the risk of limb loss for those who do not have diabetes is 2% or less [4] and, also, that this risk increases three-fold in patients with diabetes requiring pharmacological therapy (oral or insulin) [5]. #Inflammation #PeripheralArterialDisease #BareMetalStents #DrugElutingStents #PercutaneousTransluminalAngioplasty #DrugElutingBalloon #Angiology #BiochemistryOfBloodFluids #DiseasesOfTheCirculatorySystem #DiseasesOfTheLymphaticSystem #ArterialThrombosisAndEmbolism #Vasculitides #VasospasticDisorders #VenousDiseases #VenousThrombosis #ChronicVenousInsufficiency #VaricoseVeins #LymphaticDiseases #Lymphedema #BloodVesselFormation #HighBloodPressure #BloodAndHypertension #HeartAttack #BloodVesselPathology #Vasoconstriction #VascularImaging #VascularClots #AbdominalAorticAneurysms #Peertechz #PeertechzPublications #BlockageOfBloodVessels #CarotidEndarterectomy #BypassSurgeryForLegArteries #GangreneManagement #RoboticVascularSurgery #AortoIliacDisease #AorticAneurysmSurgery #AorticOcclusionSurgery #EmergencyVascularSurgery #VascularControl #TumorEmbolisation #VaricoseVeinsTreatment #LegUlcersTreatment #VascularDiseaseTreatment #MetabolicDisorders #ArterialOcclusiveDisease #AneurysmalDisease #LymphaticDisorders #ArterialDisease #VenousDisease #PulmonaryDisease #Cardiovascular #Neurovascular #Cerebrovascular #CerebralVascularDisease #VascularDiseaseSymptoms #PeripheralVascularDiseaseSymptoms #PeripheralVascularDiseaseTreatment #CarotidVascularDisease #RenalVascularDisease #HypertensiveVascularDisease #VascularHeartDisease #CollagenVascularDiseaseSymptoms #ArterioscleroticVascularDisease #CardiovascularDiseasePrevention #CirculatoryDiseases #CoronaryVascularDisease

ICYMI: Cornea Update: Selective Endothelialectomy in Peters Anomaly: A Novel Surgical Technique and Its Clinical Outcomes in Children: Purpose: This study describes the surgical outcomes of selective endothelialectomy in Peters anomaly (SEPA), a relatively new technique to manage Peters anomaly (PA). Methods: This study included 34 eyes of 28 children who had a visually significant posterior corneal defect due to PA and underwent SEPA between 2012 and 2019. A selective endothelialectomy from the posterior corneal defect was performed while preserving Descemet membrane. The primary outcome measure was the resolution of corneal opacification. The secondary outcome measures were functional vision, complications, and risk factors for failure. Results: At a mean postoperative follow-up of 0.96 ± 0.20 years, 29 eyes (85.3%) maintained a successful outcome. Mean preoperative and postoperative best-corrected visual acuities were 2.55 ± 0.13 and 1.78 ± 0.13 (P < 0.0001), respectively. Ambulatory functional visual improvement was seen in 97%, and 23% attained vision ranging between 20/190 and 20/50. Corneal opacification failed to clear in 5 eyes (15%). Risk factors associated with surgical failure were female sex (P = 0.006), disease severity (P < 0.0001), glaucoma (P = 0.001), and additional interventions after SEPA (P = 0.002). In multivariate analysis, only disease severity (ie, a type 2 PA) was a significant risk factor for the failure of SEPA. There were no sight-threatening complications. Conclusions: SEPA is a safe and effective technique in select cases of posterior corneal defect due to PA. SEPA could be a potential surgical alternative to pediatric keratoplasty or optical iridectomy in children with central corneal opacification smaller than 7 mm due to PA. http://dlvr.it/T7VZbX #Cornea #MostPopularArticles #Ophthalmology

ICYMI: Cornea Update: Selective Endothelialectomy in Peters Anomaly: A Novel Surgical Technique and Its Clinical Outcomes in Children: Purpose: This study describes the surgical outcomes of selective endothelialectomy in Peters anomaly (SEPA), a relatively new technique to manage Peters anomaly (PA). Methods: This study included 34 eyes of 28 children who had a visually significant posterior corneal defect due to PA and underwent SEPA between 2012 and 2019. A selective endothelialectomy from the posterior corneal defect was performed while preserving Descemet membrane. The primary outcome measure was the resolution of corneal opacification. The secondary outcome measures were functional vision, complications, and risk factors for failure. Results: At a mean postoperative follow-up of 0.96 ± 0.20 years, 29 eyes (85.3%) maintained a successful outcome. Mean preoperative and postoperative best-corrected visual acuities were 2.55 ± 0.13 and 1.78 ± 0.13 (P < 0.0001), respectively. Ambulatory functional visual improvement was seen in 97%, and 23% attained vision ranging between 20/190 and 20/50. Corneal opacification failed to clear in 5 eyes (15%). Risk factors associated with surgical failure were female sex (P = 0.006), disease severity (P < 0.0001), glaucoma (P = 0.001), and additional interventions after SEPA (P = 0.002). In multivariate analysis, only disease severity (ie, a type 2 PA) was a significant risk factor for the failure of SEPA. There were no sight-threatening complications. Conclusions: SEPA is a safe and effective technique in select cases of posterior corneal defect due to PA. SEPA could be a potential surgical alternative to pediatric keratoplasty or optical iridectomy in children with central corneal opacification smaller than 7 mm due to PA. http://dlvr.it/T3LVkQ #Cornea #MostPopularArticles #Ophthalmology

https://lnkd.in/g9FxZMYd Article title: Case report of optimizer implantation to modulate cardiac contractility in patients with chronic heart failure and atrial fibrillation   Author(s): Pushkareva AE; Blagodarov SI; Abdrakhmanov RE; Plotnikova MR; Dolganov AA; Mustafina IA; Zagidullin NSh   Journal: Archives of Clinical Hypertension   Journal ISSN: 2640-771X Abstract: A cardiac contractility modulation device is a new treatment used in patients with heart failure. CCM therapy is associated with an increase in physical activity tolerance, improved quality of life, reduced hospitalizations due to heart failure, and reverse remodeling of the left ventricle in patients with systolic heart failure. In this case, the clinical benefit of cardiac contractility modulation in a patient with chronic heart failure, atrial fibrillation and postinfarction left ventricle aneurysm was reported. Development of postinfarction left ventricle aneurysm in patients with reduced ejection fraction is associated with a high risk of surgical complications. However, an adequate assessment of the functional reserve of the left ventricle myocardium and the choice of surgical correction method allows for receiving favorable outcomes of surgery. We present a case of a successful combination of interventional and surgical treatment of a patient with heart failure and post-infarction left ventricular aneurysm. #ArterialBloodPressure #ArterialHypertension #BloodPressureMonitoring #BloodPressureVariability #CardiovascularRisks #CentralBloodPressure #HighBloodPressure #HypertensionDuringPregnancy #HypertensionInChildren #HypertensionInNewborn #HypertensionManagement #HypertensionNeonate #HypertensionNursing #HypertensionNutrition #HypertensionRiskFactors #HypertensionTreatment #Peertechz #PeertechzPublications #HypertensiveCrisis #HypertensiveEmergency #IdiopathicIntracranialHypertension #InducedHypertension #IntracranialHypertension #LowBloodPressure #PersistentPulmonaryHypertension #PortalHypertension #ProtopulmonaryHypertension #PulmonaryHypertension #RenalDisorders #TraumaticIntracranialHypertension