iFyber’s Post

Revolutionizing neuromuscular & cardiovascular research with 3D cell culture. Reduce batch-batch variability and monitor contraction force as a biomarker. Learn how the Cuore platform can accelerate your lead candidate selection process.

🔎 AI-powered #pathology transforms whole slide images into structured biological insights. See for yourself and register for demo access today: https://lnkd.in/eCn4xwj2 With PathExplore™ you can access spatially-resolved, single-cell insights at scale using routine H&E images. Human interpretable features (HIFs) are standardized metrics that characterize the cell and tissue composition of each WSI. PathExplore delivers >300 unique HIFs per images, including counts of cells and their spatial distribution across tissue regions, to enable streamlined and structured analysis of the #tumor #microenvironment. PathExplore™ is available across most solid tumor indications and includes indication-specific as well as indication-agnostic features that enable streamlined, pan-tumor analyses. Learn more about PathExplore today: https://lnkd.in/ghSc8VNm PathExplore™ is for research use only. Not for use in diagnostic procedures.   

Still using 2D cell cultures? It's time to think 3D. Mimic real tissues: More accurate drug testing & disease modeling for conditions like muscular dystrophy and myopathy. Accelerate drug development: Identify promising candidates faster with physiologically relevant models. Unlock the power of 3D with Cuore: Our automated contractility assay platform provides real-time insights into muscle function. Learn more and elevate your research: https://lnkd.in/d6dYhhia #3dcellculture #neuromuscular #cardiovascular #diseasemodeling

The 𝗖𝗼𝗺𝗽𝗹𝗲𝘅 𝗕𝗶𝗼𝗲𝗻𝗴𝗶𝗻𝗲𝗲𝗿𝗶𝗻𝗴 𝗳𝗼𝗿 𝗖𝗲𝗹𝗹 𝗧𝗵𝗲𝗿𝗮𝗽𝗶𝗲𝘀 𝗦𝘂𝗺𝗺𝗶𝘁 is the 𝗽𝗿𝗲𝗺𝗶𝗲𝗿 𝗲𝘃𝗲𝗻𝘁 𝗳𝗼𝗿 𝗯𝗶𝗼𝗲𝗻𝗴𝗶𝗻𝗲𝗲𝗿𝗶𝗻𝗴 𝗲𝘅𝗽𝗲𝗿𝘁𝘀 to network and gain insights into TME biology, precise payload delivery, and early risks in developing advanced logic-gated and dual-targeted cell therapies for more effective treatments.   🚨𝗝𝘂𝘀𝘁 𝗥𝗲𝗹𝗲𝗮𝘀𝗲𝗱: 𝗧𝗵𝗲 𝗳𝘂𝗹𝗹 𝗮𝗴𝗲𝗻𝗱𝗮 𝗶𝘀 𝗻𝗼𝘄 𝗮𝘃𝗮𝗶𝗹𝗮𝗯𝗹𝗲! - https://ter.li/o1ecxu   With increasing FDA scrutiny on CAR-T therapies and challenges with solid tumors, 𝘁𝗵𝗶𝘀 𝗲𝘃𝗲𝗻𝘁 𝗶𝘀𝗻'𝘁 𝗷𝘂𝘀𝘁 𝗶𝗺𝗽𝗼𝗿𝘁𝗮𝗻𝘁 - 𝗶𝘁'𝘀 𝗲𝘀𝘀𝗲𝗻𝘁𝗶𝗮𝗹.   𝗗𝗼𝗻'𝘁 𝗺𝗶𝘀𝘀 𝘆𝗼𝘂𝗿 𝗰𝗵𝗮𝗻𝗰𝗲 𝘁𝗼: 💡Overcome the tumor microenvironment 💡Enhance cell persistence 💡Ensure patient safety with cutting-edge technology   𝗙𝗶𝗻𝗱 𝗢𝘂𝘁 𝗠𝗼𝗿𝗲 𝗛𝗲𝗿𝗲 - https://ter.li/o1ecxu   #ComplexBioengineeringforCellTherapiesSummit

🎗 Gain deeper insights into the TME with our PathExplore AI analysis. Reach out to learn for a demo of our algortith and deployment platform

Scientists use three-dimensional cell culture models, such as organoids, to replicate an organ’s functionality and structure in vitro. However, researchers with limited experience often find it challenging to develop organoid models. In this webinar brought to you by Sartorius, Aitor Aguirre, Ph.D. will explain how his group produces mini hearts and uses these organoids to investigate development and disease. Register today #AD: https://ow.ly/ksgt50RuaVU

#jcdd #RecommendedPaper  Title: Electroporation Parameters for Human Cardiomyocyte Ablation In Vitro Keywords: #IrreversibleElectroporation; #AtrialFibrillation; #CardiacAblation This study presents important findings on the ability of different IRE parameters to induce human cardiomyocyte cell death. Lesion size can be tuned by appropriate choice of IRE parameters and cardiomyocytes display an upregulation of delayed cell death 24 h after electroporation, which is an important consideration for clinical practice. 👉Read more at: https://lnkd.in/g3V8BDMi

Meet our latest addition: Ncyte® Smooth Muscle Cells, our newest cell model for vascular research! Discover the benefits of working with relevant human models to study key cell functions and pharmacological responses in vitro. Learn more here: https://lnkd.in/drAAUHFy #Ncardia #NcyteSmoothMuscleCells #CardiovascularResearch

Ever wonder why some CAR-T cell therapies show better efficacy than others? This week's #RayBioRead is a groundbreaking study published in @Nature focused on the role of tonic signaling in CAR-T cell function. The research, led by Chen, J., Qiu, S., Li, W. et al, identifies positively charged patches (PCPs) on CARs as drivers behind spontaneous CAR activation. By manipulating these PCPs, researchers were able to fine-tune CAR-T cell behavior, enhancing effectiveness and reducing exhaustion. This discovery opens doors for next-gen CAR-T designs. Learn more: https://lnkd.in/gxRguPwx Featured RayBiotech Product: https://lnkd.in/e7NdF3-H

What is angiogenesis? This infographic breaks down four key assays that help us understand angiogenesis and innovate tissue repair and regeneration strategies. Plus, discover important tips for maintaining cell functionality in vitro. Download now >>> https://bit.ly/3VDhdm8