Immacolata Porreca’s Post

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Manager R&D - Horizon Discovery

Check out how we utilize the modularity of the Pin-point™ platform, the aptamer-recruited base editing system, to introduce multiple discrete modifications simultaneously, including targeted integration, and to create complex edited cell therapies in one-step process. Our paper is now published in #MolecularTherapy https://lnkd.in/dEh3g92r

An aptamer-mediated base editing platform for simultaneous knockin and multiple gene knockout for allogeneic CAR-T cells generation

An aptamer-mediated base editing platform for simultaneous knockin and multiple gene knockout for allogeneic CAR-T cells generation

sciencedirect.com

Dario Palmieri

Assistant Professor, Department of Cancer Biology and Genetics; Director, Gene Editing Shared Resource presso The Ohio State University Wexner Medical Center

4mo

So cool!!

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